Skip directly to search Skip directly to A to Z list Skip directly to site content
CDC Home

Notice to Readers FDA Approval of Change in Pediatric Formulation for Recombivax HB{Registered}

Effective August 27, 1998, the Merck Vaccine Division (Merck & Co., Inc., West Point, Pennsylvania) discontinued distribution and production of the 2.5-ug dose of Recombivax HB{Registered} * pediatric hepatitis B vaccine, which was licensed by the Food and Drug Administration for infants of hepatitis B surface antigen (HBsAg)-negative mothers and children aged less than or equal to 10 years. The 2.5-ug dose was replaced with a 5.0-ug dose previously used for vaccination of adolescents and infants of HBsAg-positive mothers. To simplify the vaccination schedule for infants and children, the Advisory Committee on Immunization Practices recommends use of the 5.0-ug dose for all children and adolescents aged 0-19 years. Either the 2.5-ug dose or the 5.0-ug dose may be used to complete any vaccine series already started for children aged less than or equal to 10 years, regardless of the initiating dose of vaccine. Children who have completed the hepatitis B vaccination series with the 2.5-ug dose do not need to be revaccinated.

  • Use of trade names and commercial sources is for identification only and does not imply endorsement by CDC or the U.S. Department of Health and Human Services.



Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of Health and Human Services.

References to non-CDC sites on the Internet are provided as a service to MMWR readers and do not constitute or imply endorsement of these organizations or their programs by CDC or the U.S. Department of Health and Human Services. CDC is not responsible for the content of pages found at these sites. URL addresses listed in MMWR were current as of the date of publication.


All MMWR HTML versions of articles are electronic conversions from typeset documents. This conversion might result in character translation or format errors in the HTML version. Users are referred to the electronic PDF version (http://www.cdc.gov/mmwr) and/or the original MMWR paper copy for printable versions of official text, figures, and tables. An original paper copy of this issue can be obtained from the Superintendent of Documents, U.S. Government Printing Office (GPO), Washington, DC 20402-9371; telephone: (202) 512-1800. Contact GPO for current prices.

**Questions or messages regarding errors in formatting should be addressed to mmwrq@cdc.gov.

 
USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO
A-Z Index
  1. A
  2. B
  3. C
  4. D
  5. E
  6. F
  7. G
  8. H
  9. I
  10. J
  11. K
  12. L
  13. M
  14. N
  15. O
  16. P
  17. Q
  18. R
  19. S
  20. T
  21. U
  22. V
  23. W
  24. X
  25. Y
  26. Z
  27. #