Neglected Parasitic Infections in the United States (NPIs)
Most people think of parasitic diseases occurr in poor and developing countries, and is something they might pick up on a trip to a foreign country. However, parasitic infections also occur in the United States. In some cases, they affect millions of people.
- Impact millions: Parasitic infections can go unnoticed, with few symptoms. But many times these infections cause serious illnesses, including seizures, blindness, pregnancy complications, heart failure, and even death.
- No one is immune: Anyone, regardless of race or economic status, can become infected.
- Can be prevented: CDC has targeted five neglected parasitic infections (NPIs) in the United State as priorities for public health action. These infections are considered neglected because relatively little attention has been devoted to their surveillance, prevention, and/or treatment. NPIs were prioritized based on the numbers of people infected, the severity of the illnesses, or our ability to prevent and treat them. The NPIs include Chagas disease, cysticercosis (neurocysticercosis), toxocariasis, toxoplasmosis, and trichomoniasis.
CDC Media Relations
Tom Frieden, MD, MPH
“Parasitic infections affect millions around the world causing seizures, blindness, infertility, heart failure, and even death. They’re more common in the US than people realize and yet there is so much we don’t know about them. We need research to learn more about these infections and action to better prevent and treat them."
Tom Frieden, MD, MPH - Director of the Centers for Disease Control and Prevention
Monica Parise, MD
“These neglected parasitic infections, or NPIs, affect millions of Americans. But they can be prevented. We can best prevent and control these diseases by better defining their scope and determining what puts people at risk to get them. We need to improve methods for diagnosing them and develop better medications for preventing and treating them. We should also look at ways to expand the use of existing public health interventions that work."
Monica Parise, MD - Chief, Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health
Susan P. Montgomery, DVM, MPH
“Chagas disease can cause severe heart problems, including heart failure, stroke, and even death. There are more than 300,000 people with Chagas disease living in the United States and most don’t know they have this infection. Most health care providers in the United States aren’t familiar with the disease, so they don’t think to test their patients who might be at risk, or they might not know how to treat them."
Susan P. Montgomery, DVM, MPH - Epidemiology Team Lead, Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health
Paul T. Cantey, MD, MPH
“Neurocysticercosis is the leading cause of infectious epilepsy in many parts of the world. This totally preventable infection can have a devastating effect on people’s lives and is sometimes fatal. Despite advances in our understanding, we still have many unanswered questions. CDC will continue to do its part to improve our ability to diagnose, manage, and prevent this disease of neglected people."
Paul T. Cantey, MD, MPH - Epidemiologist, Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health
Jeffrey L. Jones, MD, MPH
“Toxoplasma gondii is one of the most common parasites that infects humans and infects millions of people in the United States. Better tools are needed to diagnose and treat toxoplasmosis."
Jeffrey L. Jones, MD, MPH - Medical Epidemiologist, Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health
Dana M. Woodhall, MD
“Toxocariasis is a preventable parasitic infection. CDC is working to educate both healthcare professionals and the general public about this disease in an effort to prevent further infections from occurring."
Dana M. Woodhall, MD - Medical Epidemiologist, Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health
W. Evan Secor, PhD
“Trichomonas vaginalis was once regarded as an annoying infection and it was thought that women who were not cured did not follow the prescribed treatment. It is gratifying to see those attitudes changing among clinicians and recognition of both the health consequences of trichomoniasis and the reality of drug resistance."
W. Evan Secor, PhD - Team Lead, Elimination and Control Laboratory, Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health
- CDC Chagas Disease Printable Resources
- CDC Chagas Disease Printable Resources (in Spanish)
- CDC “Our Global Voices” Blog: Chagas Disease
- CDC Toxocariasis Printable Resources
- CDC Toxoplasmosis: An Important Message for Cat Owners
- CDC Trichomoniasis Fact Sheet
- CDC Trichomoniasis Pamphlet
- CDC DPDx, Parasitic Diseases Diagnostic Resources
Health Communication Materials
- CDC Neglected Parasitic Infections Fact Sheet
- NPI: Chagas Disease Fact Sheet
- NPI: Cysticercosis Fact Sheet
- NPI: Toxocariasis Fact Sheet
- NPI: Toxoplasmosis Fact Sheet
- NPI: Trichomoniasis Fact Sheet
- Congenital Transmission of Chagas Disease – Virginia, 2010 (MMWR)
- Blood Donor Screening for Chagas Disease — United States, 2006–2007 (MMWR)
- Infection of Kissing Bugs with Trypanosoma cruzi, Tucson, Arizona, USA (EID)
- Physician Awareness of Chagas Disease, USA (EID)
- Ocular Toxocariasis — United States, 2009–2010 (MMWR)
- Ocular toxocariasis: epidemiologic, anatomic, and therapeutic variations based on a survey of ophthalmic subspecialists (Ophthalmology)
- Preventing congenital toxoplasmosis (MMWR)
- Risk factors for Toxoplasma gondii infection in the United States (Clin Infect Dis)
- Toxoplasma gondii Infection in the United States, 1999–2000 (EID)
- AJTMH Special Supplement on NPIs in the United States
- NPIs: Medscape Slide Show
- WHO Chagas Disease
- PAHO Chagas Disease
- Chagas’ Biovigilance Network Map
- NIH North American Cysticercosis Consortium
- APHL: Advances in Laboratory Detection of Trichomonas vaginalis
Guidelines for Prevention/Treatment of Toxoplasmosis in Persons with HIV/AIDS
- Page last reviewed: May 9, 2014
- Page last updated: May 9, 2014
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