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CDC Science Clips: Volume 5, Issue 19, May 13, 2013

 

Science Clips recognizes the observance of Women's Health Week with several relevant featured articles. A Cochrane review of combination injectable contraceptives (CICs) led by MF Gallo identifies multiple research priorities for improving CIC acceptability. Writing in the journal AIDS Care, A Medley and colleagues advocate for couples HIV testing and counseling and identify evidence-based interventions that can be offered to serodiscordant couples. A CDC/WHO collaboration by S Gupta et al reviews antiretroviral therapy (ART) initiation guidelines from 70 countries for a variety of patient groups, including serodiscordant couples; they conclude that in many countries and for many specific patient populations, country guidelines differ from WHO recommendations.

Historically, hospitals have served as important venues for public health research. Several of this week's features embody that tradition. A large group led by K Chheng prospectively studied febrile illness requiring hospitalization over a one year period in a Cambodian province, finding a defined viral or bacterial cause for almost half of febrile episodes. An analysis from a U.S. tertiary care hospital conducted by J Sharp et al finds further evidence of the emergence of human parechovirus as a cause of infant central nervous system infection. Encouraging news about the occurrence of hospital-associated infections is provided by ME Wise along with multiple CDC colleagues, who report decreasing occurrence of central-line associated bloodstream infections in critical care patients over the past two decades.

As diverse emerging viruses continue to make headlines, diverse aspects of virology play a prominent role in Clips this week. A meta-analysis of observational studies of eradication of hepatitis C virus infection, conducted by RL Morgan and collaborators, finds "moderate quality" evidence of resultant reduced incidence of hepatocellular carcinoma. KM Gustin and colleagues from the CDC Influenza Division report that "…ferrets infected by highly transmissible influenza viruses exhale a greater number of aerosol particles and more infectious virus…compared to ferrets infected by influenza viruses that do not readily transmit". The authors state that their findings support the possibility of aerosol transmission of influenza virus. A review of the use of mass spectrometry in the molecular diagnosis of viral infections, authored by LM Ganova-Raeva and YE Khudyakov, hints at the potential importance of advanced molecular detection.

The analysis by X Zhang and colleagues concerning childhood obesity brings to mind the saying "think globally, act locally." Writing in the CDC e-journal Preventing Chronic Disease, the authors conclude from 2007 National Survey of Children's Health data that location may be as significant a risk factor as race and ethnicity.

John Iskander
Editor, Science Clips


  1. Top Ten Articles of the Week
    Selected weekly by a senior CDC scientist from the standard sections listed below.
  2. CDC Authored Publications
    The names of CDC authors are indicated in bold text.
    Articles published in the past 6-8 weeks authored by CDC or ATSDR staff.
  3. Public Health Articles Noted in the Media
    Articles about important public health topics that have been mentioned in the press.

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CDC Science Clips Production Staff
John Iskander, MD MPH, Editor
Rebecca Satterthwaite, MS, Librarian
Gail Bang, MLIS, Librarian
Deidre Mallett, MLS, Librarian
Kathleen Connick, MSLS, Librarian
Barbara Landreth, MLS, Librarian
Joseph Dunlap, Web Developer
Joe Bryce, Web Developer

____

DISCLAIMER: Articles listed in the CDC Science Clips are selected by the Stephen B. Thacker CDC Library to provide current awareness of the public health literature. An article's inclusion does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.


 
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