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HPV Vaccine Safety

doctor talking with patients

The human papillomavirus (HPV) vaccines are safe, effective, and offer lasting protection against most cancers caused by HPV infection.

Both HPV vaccines- Gardasil® and Cervarix®- went through years of extensive safety testing before they were licensed by the U.S. Food and Drug Administration (FDA). Gardasil® was studied in clinical trials with 29,000 females and males, and Cervarix® trials included more than 30,000 females. No serious safety concerns were identified in these clinical trials. FDA only licenses a vaccine if it is safe, effective, and the benefits outweigh the risks. CDC and FDA continue to monitor both vaccines to make sure they are safe and beneficial for the public.

Like any vaccine or medicine, HPV vaccines might cause mild reactions. The most common symptoms are pain or redness in the arm where the shot is given. HPV vaccines have not been associated with any long-term health problems.

Read more: Summaries, reports, and frequently asked questions about HPV Vaccine Safety


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