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CDC HomeHIV/AIDS > Topics > Research > Prevention Research Synthesis > Compendium of Evidence-Based HIV Prevention Interventions

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Good-Evidence Risk Reduction Interventions
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A complete listing of good-evidence risk reduction (RR) interventions is provided below.

Good-Evidence RR interventions include interventions that focus on HIV-related risk behaviors, have been sufficiently evaluated, and have shown significant effects in eliminating or reducing sex- or drug-related risk behaviors, reducing the rate of new HIV/STD infections, or increasing HIV-protective behaviors. These interventions meet the PRS RR efficacy criteria for good-evidence ILI/GLI or good-evidence CLI and are considered to be scientifically sound and to provide sufficient scientific evidence of efficacy.

The PRS efficacy review process has identified
25 good-evidence individual- and group-level RR interventions and
5 good-evidence community-level interventions

(through December 2009)

(Updated on April 18, 2011)

KEY: MA=medication adherence; TxE=treatment experienced; TxN=treatment naīve; HS=Heterosexual; HIV+=HIV-positive; HR=High-risk; MSM=Men who have sex with men; DU=Drug users; M=Male; F=Female; T=Transgender; W=White; AA=African American; AI=American Indian; H=Hispanic; API=Asian/Pacific Islander; O=Other racial/ethnic group; GLI=group-level intervention; ILI=individual-level intervention; CLI = community-level intervention

  • ARK
    Good
    Risk category: HR Youth
    Sex: 68% M, 32% F
    Race: 75% W, 22% AA, 2% AI, 1% H
    Intervention level: GLI
  • BRAINE
    Good
    Risk category: DU
    Sex: 62% M, 38% F
    Race: 90% W, 10% O
    Intervention level: ILI
  • Cognitive Behavioral STD/HIV Risk-Reduction
    Good
    Risk category: HS Adult
    Sex: 63% M, 37% F
    Race: 46% AA, 29% W, 17% H, 8% O
    Intervention level: ILI
  • Community PROMISE
    Good
    Risk category: DU, HR Youth, HS Adult, MSM
    Sex: 45% M, 55% F
    Race: 54% AA, 22% W, 19% H, 5% O
    Intervention level: CLI
  • Condom Promotion
    Good
    Risk category: HS Adult
    Sex: 100% F
    Race: 79% W, 8% H, 5% API, 4% AI, 3% AA, 1% O
    Intervention level: GLI
  • Doing Something Different
    Good
    Risk category: HS Adult
    Sex: 71% M, 29% F
    Race: 92% AA, 8% O
    Intervention level: GLI
  • DUIT
    Good
    Risk category: DU
    Sex: 66% M, 33% F, 1% T
    Race: 63% W, 17% H, 11% O, 8% AA
    Intervention level: GLI
  • Focus on Youth
    Good
    Risk category: HR Youth
    Sex: 56% M, 44% F
    Race: 100% AA
    Intervention level: GLI
  • Healthy Love NEW 2010
    Good
    Risk category: HS Adult
    Sex: 100% F
    Race: 97% AA, 3% O
    Intervention level: GLI
  • HIV Education and Testing
    Good
    Risk category: HS Adult
    Sex: 67% M, 33% F
    Race: 88% AA, 12% O
    Intervention level: ILI
  • Insights
    Good
    Risk category: HS Adult
    Sex: 100% F
    Race: 69% W, 19% AA, 12% O
    Intervention level: ILI
  • Intensive AIDS Education
    Good
    Risk category: HR Youth, DU
    Sex: 100% M
    Race: 66% AA, 33% H, 2% W
    Intervention level: GLI
  • Mpowerment
    Good
    Risk category: MSM
    Sex: 100% M
    Race: 81% W, 7% API, 6% H, 4% AA, 2% O
    Intervention level: CLI
  • Nia
    Good
    Risk category: HS Adult
    Sex: 100% M
    Race: 100% AA
    Intervention level: GLI
  • Options/Opciones Project
    Good
    Risk category: HIV+
    Sex
    : 58% M, 42% F
    Race: 38% AA, 35% H, 22% W, 5% O
    Intervention level: ILI
  • Partnership for Health (Loss-Frame)
    Good
    Risk category: HIV+
    Sex: 86% M, 14% F
    Race: 41% W, 37% H, 16% AA, 6% O
    Intervention level: ILI
  • POL
    Good
    Risk category: MSM
    Sex: 100% M
    Race: 86% W, 14% AA or H
    Intervention level: CLI
  • RAPP
    Good
    Risk category: HS Adult
    Sex: 100% F
    Race: 73% AA, 27% O
    Intervention level: CLI
  • REAL Men
    Good
    Risk category: HR Youth
    Sex: 100% M
    Race: 96% AA
    Intervention level: GLI
  • Real Men Are Safe (REMAS) NEW 2009 
    Good

    Risk category: DU
    Sex: 100% M
    Race: 56% W, 28% AA, 13% H, 2% AI, 1% API, <1% O
    Intervention level: GLI
  • RESPECT
    Good
    Brief Counseling (Best Evidence)
    Enhanced Counseling
    (Good Evidence)

    Risk category: HS Adult
    Sex: 57% M, 43% F
    Race: 59% AA, 19% H, 16% W, 6% O
    Intervention level: ILI
  • Safe on the Outs NEW 2010
    Good
    Risk category: HR Youth
    Sex: 83% M, 17% F
    Race: 37% W, 28% H, 15% O, 13% AA, 5% AI, 3% API
    Intervention level: GLI
  • Safer Sex NEW 2009
    Good
    Risk category: HR Youth
    Sex: 100% F
    Race: 49% AA, 18% H, 17% O, 14% W
    Intervention level: ILI
  • Safer Sex Skills Building (SSSB) NEW 2009
    Good

    Risk category: HS Adult, DU
    Sex: 100% F
    Race: 58% W, 24% AA, 9% H, 9% O
    Intervention level: GLI
  • Safety Counts
    Good
    Risk category: DU
    Sex: 67% M, 33% F
    Race: 47% AA, 28% W, 20% H, 4% AI, 1% API
    Intervention level: GLI
  • SEPA
    Good
    Risk category: HS Adult
    Sex: 100% F
    Race: 100% H
    Intervention level: GLI
  • Sniffer
    Good
    Risk category: DU
    Sex: 70% M, 30% F
    Race: 51% W, 26% AA, 23% H
    Intervention level: GLI
  • Street Smart
    Good
    Risk category: HR Youth
    Sex: 51% M, 49% F
    Race: 53% AA, 30% H, 16% O
    Intervention level: GLI
  • Teen Health Project
    Good
    Risk category: HR Youth
    Sex: 50% M, 50% F
    Race: 51% AA, 20% A, 20% O, 5% W, 3%H, 1% AI
    Intervention level: CLI
  • TLC
    Good
    Risk category: HIV+, HR Youth
    Sex: 72% M, 28% F
    Race: 37% H, 27% AA, 19% W, 17% O
    Intervention level: GLI

Back to Risk Reduction Chapter–Listing of EBIs

 

Last Modified: August 12, 2011
Last Reviewed: August 12, 2011
Content Source:
Divisions of HIV/AIDS Prevention
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention
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