The HIV/AIDS Prevention Research Synthesis (PRS) Project, through its ongoing efficacy review process, identifies evidence-based HIV behavioral interventions to help HIV prevention planners and providers in the U.S. select interventions most appropriate for their communities. These are listed in the 2008 Compendium of Evidence-based HIV Prevention Interventions.

NEW! The PRS review of community-level HIV behavioral interventions is now complete. New efficacy criteria were developed for evaluating community-level interventions through multiple consultations with HIV researchers and methodologists. As a result, 5 new evidence-based community-level interventions were added, on May 7, 2009, to the 2008 Compendium. Also, 1 new evidence-based individual-level intervention was added.

All of the interventions cataloged on this site are evidence-based behavioral interventions for persons at high risk of acquiring or transmitting HIV. These interventions represent the strongest HIV behavioral interventions in the literature to date that have been rigorously evaluated and have demonstrated efficacy in reducing HIV or STD incidence or HIV-related risk behaviors (e.g., unprotected sex, needle sharing) or promoting safer behaviors (e.g., being abstinent, using condoms).

We regularly update this website with the most recent evidence-based interventions as they are identified through our on-going efficacy review process.

Please visit this site periodically for updates.