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Compendium of Evidence-Based Interventions and
Best Practices for HIV Prevention

Other HIV Risk Reduction Interventions from the Original Compendium

NOTE: evidence criteria links on this page need to be updated, once those pages exist.

The original PRS efficacy review, including studies published between 1988 and 1996, identified 24 evidence-based behavioral interventions. These interventions were summarized in the Compendium of HIV Prevention Interventions with Evidence of Effectiveness.  This original review was based on the Compendium criteria. Since then PRS strengthened its criteria for identifying evidence-based, individual- and group-level behavioral interventions. More details about the current criteria can be found at Efficacy Reviews.

Half of the 24 HIV behavioral interventions that were identified in the original Compendium of HIV Prevention Interventions with Evidence of Effectiveness using the less rigorous Compendium criteria meet either the current best-evidence criteria or the current good-evidence criteria. There are 8 of the original 24 Compendium interventions that do not meet the current criteria for best- or good-evidence, most commonly due to low retention rates or small analytical sample sizes. These ILIs and GLIs are listed below, and most fit in Tier III of the Tiers of Evidence Framework

CDC-funded programs using DEBIs that among the 8 ILIs/GLIs not meeting the best-evidence or good-evidence criteria can continue implementing these interventions for the time being. Agencies that are planning to implement a new ILI, GLI, or CLI are encouraged to select an intervention from among the best-evidence or good-evidence ILI, GLI, and CLI interventions.

KEY: HS=Heterosexual; HIV+=HIV-positive; HR=High-risk; MSM=Men who have sex with men; DU=Drug users; M=Males; F=Females; W=White; AA=African American; AI=American Indian; H=Hispanic; API=Asian/Pacific Islander; O=Other racial/ethnic group; GLI=group-level intervention; ILI=individual-level intervention

Individual-level and group-level interventions meeting previous Compendium criteria: 

  • Behavioral Self-Management and Assertion Skills
    Risk category: MSM
    Sex: 100% M
    Race: 87% W, 13% AA or H
    Intervention level: GLI
  • Cognitive-Behavioral Skills Training Group
    Risk category: HS Adult
    Sex: 100% F
    Race: 87% AA, 6% W, 4% AI, 3% H
    Intervention level: GLI
  • Condom Skills Education
    Risk category: HS Adult
    Sex: 69% M, 41% F
    Race: 76% AA, 15% H, 9% O
    Intervention level: GLI
  • Enhanced AIDS Education
    Risk category: DU
    Sex: 67% M, 33% F
    Race: 81% W, 19% O
    Intervention level: ILI , GLI
  • Reducing AIDS Risk Activity
    Risk category: HS Adult
    Sex: 100% F
    Race: 57% AA, 40% W, 3% O
    Intervention level: GLI
  • SISTA
    Risk category: HS Adult
    Sex: 100% F
    Race: 100% AA
    Intervention level: GLI
  • Skill Building
    Risk category: DU
    Sex: 100% F
    Race: 64% H, 36% AA
    Intervention level: GLI
  • Small-group Lecture Plus Skill Training
    Risk category: MSM
    Sex: 100% M
    Race: 95% W, 2% AA, 1% API, 1% H, 1% O
    Intervention level: ILI , GLI

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  • Page last reviewed: April 20, 2013
  • Page last updated: April 20, 2013
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