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Compendium of Evidence-Based Interventions and
Best Practices for HIV Prevention

Complete Listing of Risk Reduction Evidence-based Behavioral Interventions

  • AMIGAS NEW 2014
    Best

    Risk category
    : Heterosexual Adult
    Sex: 100% Female
    Race: 100% Latina
    Intervention level: Group-level
  • Assisting in Rehabilitating Kids (ARK)
    Good
    Risk category: High Risk Youth
    Sex: 68% Male, 32% Female
    Race: 75% White, 22% African American, 2% American Indian, 1% Hispanic
    Intervention level: Group-level
  • Becoming a Responsible Teen (BART)
    Best
    Risk category: High Risk Youth
    Sex: 28% Male, 72% Female
    Race: 100% African American
    Intervention level: Group-level
  • Be Proud! Be Responsible!
    Best
    Risk category
    : High Risk Youth
    Sex: 100% Male
    Race: 100% African American
    Intervention level: Group-level
  • Brief Alcohol Intervention for Needle Exchangers (BRAINE)
    Good
    Risk category: Drug Users
    Sex: 62% Male, 38% Female
    Race: 90% White, 10% Other
    Intervention level: Individual-level
  • Brief Group Counseling
    Best
    Risk category: MSM
    Sex: 100% Male
    Race: 100% Asian/Pacific Islander
    Intervention level: Group-level
  • Centering Pregnancy Plus (CPP)
    Best

    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 80% African American, 13% Hispanic, 6% White, 1% Other
    Intervention level: Group-level
  • CHAT NEW 2014
    Best
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 98% African American, 2% White, 1% Other
    Intervention level: Group-level
  • Choices
    Best
    Risk category: Heterosexual Adult
    Sex
    : 100% Female
    Race: 54% White, 29% African American, 5% American Indian, 3% Hispanic, 3% Asian/Pacific Islander, 6% Other
    Intervention level: Group-level
  • Choosing Life: Empowerment, Actions, Results (CLEAR)
    Best
    Risk category: HIV+, High Risk Youth, Drug Users
    Sex
    : 78% Male, 22% Female
    Race: 42% Hispanic, 26% African American, 23% White, 8% Other
    Intervention level: Individual-level
  • Cognitive Behavioral STD/HIV Risk-Reduction
    Good
    Risk category: Heterosexual Adult
    Sex: 63% Male, 37% Female
    Race: 46% African American, 29% White, 17% Hispanic, 8% Other
    Intervention level: Individual-level
  • Communal Effectance-AIDS Prevention (CE-AP)
    Best
    Risk category: Heterosexual Adult
    Sex
    : 100% Female
    Race: 55% African American, 42% White, 3% Other
    Intervention level: Group-level
  • Community Promise
    Good
    Risk category: Drug Users, High Risk Youth, Heterosexual Adult, MSM
    Sex: 45% Male, 55% Female
    Race: 54% African American, 22% White, 19% Hispanic, 5% Other
    Intervention level: Community-level
  • Condom Promotion
    Good
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 79% White, 8% Hispanic, 5% Asian/Pacific Islander, 4% American Indian, 3% African American, 1% Other
    Intervention level: Group-level
  • Connect: Couple
    Best
    Risk category: Heterosexual Adult
    Sex
    : 50% Male, 50% Female
    Race: 55% African American, 39% Hispanic, 6% Other
    Intervention level: Group-level
  • Connect: Woman Alone
    Best
    Risk category: Heterosexual Adult
    Sex
    : 50% Male, 50% Female
    Race: 55% African American, 39% Hispanic, 6% Other
    Intervention level: Individual-level
  • Connect 2 NEW 2014
    Best
    Risk category
    : Heterosexual Adult
    Sex: 50% Female, 50% Male
    Race: 50% African American, 28% Hispanic, 11% People of Color, 11% White
    Intervention level: Couple-level
  • ¡Cuídate!
    Best
    Risk category: High Risk Youth
    Sex: 45% Male, 55% Female
    Race: 100% Hispanic
    Intervention level: Group-level
  • Doing Something Different
    Good
    Risk category: Heterosexual Adult
    Sex: 71% Male, 29% Female
    Race: 92% African American, 8% Other
    Intervention level: Group-level
  • Drug Users Intervention Trial (DUIT)
    Good
    Risk category: Drug Users
    Sex: 66% Male, 33% Female, 1% Transgender
    Race: 63% White, 17% Hispanic, 11% Other, 8% African American
    Intervention level: Group-level
  • Eban NEW 2014
    Best
    Risk category: HIV+, Heterosexual Adult
    Sex: 50% Female, 50% Male
    Race: 100% African American
    Intervention level: Couple-level
  • EXPLORE
    Best
    Risk category: MSM
    Sex
    : 100% Male
    Race: 72% White, 15% Hispanic, 7% African American, 6% Other
    Intervention level: Individual-level
  • Familias Unidas NEW 2014
    Best
    Risk category
    : High Risk Youth
    Sex: 64% Male, 36% Female
    Race: 100% Hispanic
    Intervention level: Group-level
  • Female and Culturally Specific Negotiation
    Best
    Risk category: Heterosexual Adult, Drug Users
    Sex
    : 100% Female
    Race: 100% African American
    Intervention level: Individual-level
  • Female Condom Skills Training
    Best
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 64% White, 17% Hispanic, 11% African American, 6% Asian/Pacific Islander, 2% Other
    Intervention level: Group-level
  • Project FIO (The Future Is Ours)
    Best
    Risk category: Heterosexual Adult
    Sex
    : 100% Female
    Race: 73% African American, 17% Hispanic, 10% White, 0.3% Asian/Pacific Islander
    Intervention level: Group-level
  • Focus on the Future
    Best
    Risk category: Heterosexual Adult
    Sex: 100% Male
    Race: 100% African American
    Intervention level: Individual-level
  • Focus on Youth
    Good
    Risk category: High Risk Youth
    Sex: 56% Male, 44% Female
    Race: 100% African American
    Intervention level: Group-level
  • FOY + ImPACT
    Best
    Risk category: High Risk Youth
    Sex
    : 42% Male, 58% Female
    Race: 100% African American
    Intervention level: Group-level
  • Health Improvement Project (HIP)
    Best
    Risk category: Heterosexual Adult
    Sex
    : 45% Male, 54% Female
    Race: 67% White, 21% African American, 12% Other
    Intervention level: Group-level
  • Healthy Living Project (HLP)
    Best
    Risk category: HIV+
    Sex: 79% Male, 21% Female
    Race: 45% African American, 32% White, 15% Hispanic, 8% Other
    Intervention level: Individual-level
  • Healthy Love
    Good
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 97% African American, 3% Other
    Intervention level: Group-level
  • Healthy Relationships
    Best
    Risk category: HIV+
    Sex
    : 70% Male, 29% Female, 1% Transgender
    Race: 74% African American, 22% White, 4% Other
    Intervention level: Group-level
  • HIV Education and Testing
    Good
    Risk category: Heterosexual Adult
    Sex: 67% Male, 33% Female
    Race: 88% African American, 12% Other
    Intervention level: Individual-level
  • HoMBReS
    Best

    Risk category: Heterosexual Adult
    Sex: 100% Male
    Race: 100% Hispanic
    Intervention level: Community-level
  • HORIZONS
    Best
    Risk category: High Risk Youth
    Sex: 100% Female
    Race: 100% African American
    Intervention level: Group-level
  • Project IMAGE NEW 2014
    Good
    Risk category: High Risk Youth
    Sex: 100% Female
    Race: 84% Mexican American, 16% African American
    Intervention level: Group-level
  • In The Mix NEW 2014
    Best
    Risk category: HIV+
    Sex: 64% Male, 29% Female, 7% Transgender
    Race: 91% African American, 6% White, 2% Latino, 2% Other
    Intervention level: Group-level
  • Insights
    Good
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 69% White, 19% African American, 12% Other
    Intervention level: Individual-level
  • Intensive AIDS Education
    Good
    Risk category: High Risk Youth, Drug Users
    Sex: 100% Male
    Race: 66% African American, 33% Hispanic, 2% White
    Intervention level: Group-level
  • LIFT  
    Best
    Risk category: HIV+ w/ Childhood Sexual Abuse
    Sex: 47% Male, 53% Female
    Race: 68% African American, 17% Hispanic, 10% White, 5% Other
    Intervention level: Group-level
  • “light”
    Best
    Risk category: Heterosexual Adult
    Sex: 42% Male, 58% Female
    Race: 74% African American, 25% Hispanic, 1% Other
    Intervention level: Group-level
  • Many Men, Many Voices (3MV)
    Best
    Risk category: MSM
    Sex: 100% Male
    Race: 100% African American
    Intervention level: Group-level
  • Modelo de Intervención Psicomédica (MIP)
    Best
    Risk category: Drug Users
    Sex
    : 89% Male, 11% Female
    Race: 100% Hispanic
    Intervention level: Individual-level
  • Mpowerment
    Good
    Risk category: MSM
    Sex: 100% Male
    Race: 81% White, 7% Asian/Pacific Islander, 6% Hispanic, 4% African American, 2% Other
    Intervention level: Community-level
  • Motivational Interviewing-based HIV Risk Reduction
    Best
    Risk category: Heterosexual Adult, Drug Users
    Sex: 100% Female
    Race: 54% White, 18% African American, 6% Hispanic, 6% American Indian, 15% Other
    Intervention level: Individual-level
  • Nia
    Good
    Risk category: Heterosexual Adult
    Sex: 100% Male
    Race: 100% African American
    Intervention level: Group-level
  • Options/Opciones Project
    Good
    Risk category: HIV+
    Sex
    : 58% Male, 42% Female
    Race: 38% African American, 35% Hispanic, 22% White, 5% Other
    Intervention level: Individual-level
  • Preventing AIDS through Live Movement and Sound (PALMS) NEW 2014
    Good
    Risk category
    : High Risk Youth
    Sex: 100% Male
    Race: 79% African American, 8% Latino, 6% White, 7% Mixed/Other
    Intervention level: Group-level
  • Partnership for Health (Loss-Frame)
    Good
    Risk category: HIV+
    Sex: 86% Male, 14% Female
    Race: 41% White, 37% Hispanic, 16% African American, 6% Other
    Intervention level: Individual-level
  • Personalized Cognitive Risk-Reduction Counseling
    Best
    Risk category: MSM
    Sex
    : 100% Male
    Race: 74% White, 11% Hispanic, 6% Asian/Pacific Islander, 3% African American, 6% Other
    Intervention level: Individual-level
  • POL
    Good
    Risk category: MSM
    Sex: 100% Male
    Race: 86% White, 14% African American or Hispanic
    Intervention level: Community-level
  • Positive Choice: Interactive Video Doctor
    Best
    Risk category: HIV+
    Sex: 79% Male, 21% Female
    Race: 50% African American, 29% White, 13% Hispanic, 8% Other
    Intervention level: Individual-level
  • Real AIDS Prevention Project (RAPP)
    Good
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 73% African American, 27% Other
    Intervention level: Community-level
  • REAL Men
    Good
    Risk category: High Risk Youth
    Sex: 100% Male
    Race: 96% African American
    Intervention level: Group-level
  • Real Men Are Safe (REMAS)
    Good

    Risk category: Drug Users
    Sex: 100% Male
    Race: 56% White, 28% African American, 13% Hispanic, 2% American Indian, 1% Asian/Pacific Islander, <1% Other
    Intervention level: Group-level
  • RESPECT: Brief Counseling
    Best
    Risk category: Heterosexual Adult
    Sex: 57% Male, 43% Female
    Race: 59% African American, 19% Hispanic, 16% White, 6% Other
    Intervention level: Individual-level
  • RESPECT: Enhanced Counseling
    Good
    Risk category: Heterosexual Adult
    Sex: 57% Male, 43% Female
    Race: 59% African American, 19% Hispanic, 16% White, 6% Other
    Intervention level: Individual-level
  • RESPECT: Brief Counseling + Booster
    Best
    Risk category: Heterosexual Adult
    Sex: 54% Male, 46% Female
    Race: 51% African American, 22% White, 18% Hispanic, 9% Other
    Intervention level: Individual-level
  • SAFE (Standard Version) 
    Best
    Risk category: Heterosexual Adult
    Sex
    : 100% Female
    Race: 77% Hispanic, 23% African American
    Intervention level: Group-level
  • Safe in the City
    Best
    Risk category: Heterosexual Adult
    Sex: 70% Male, 30% Female
    Race: 46% White, 25% Hispanic, 18% African American, 11% Other
    Intervention level: Individual-level
  • Safe on the Outs
    Good
    Risk category: High Risk Youth
    Sex: 83% Male, 17% Female
    Race: 37% White, 28% Hispanic, 15% Other, 13% African American, 5% American Indian, 3% Asian/Pacific Islander
    Intervention level: Group-level
  • Safer Sex
    Good
    Risk category: High Risk Youth
    Sex: 100% Female
    Race: 49% African American, 18% Hispanic, 17% Other, 14% White
    Intervention level: Individual-level
  • Safer Sex Skills Building (SSSB)
    Good

    Risk category: Heterosexual Adult, Drug Users
    Sex: 100% Female
    Race: 58% White, 24% African American, 9% Hispanic, 9% Other
    Intervention level: Group-level
  • SafeTalk NEW 2014
    Good
    Risk category
    : HIV+, Heterosexual Adult
    Sex: 65% Male, 35% Female
    Race: 71% African American, 20% White, 8% Other
    Intervention level: Individual-level
  • Safety Counts
    Good
    Risk category: Drug Users
    Sex: 67% Male, 33% Female
    Race: 47% African American, 28% White, 20% Hispanic, 4% American Indian, 1% Asian/Pacific Islander
    Intervention level: Group-level
  • Self-Help in Eliminating Life-Threatening Diseases (SHIELD)
    Best
    Risk category: Drug Users
    Sex
    : 61% Male, 39% Female
    Race: 94% African American, 6% Other
    Intervention level: Group-level
  • SEPA
    Good
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 100% Hispanic
    Intervention level: Group-level
  • Seropositive Urban Men’s Intervention Trial (SUMIT)
    Best
    Risk category: HIV+, MSM
    Sex: 100% Male
    Race: 51% White, 23% African American, 17% Hispanic, 1% Asian/Pacific Islander, 1% American Indian, 7% Other
    Intervention level: Group-level
  • Sistering, Informing, Healing, Living, and Empowering (SiHLE)
    Best
    Risk category: High Risk Youth
    Sex
    : 100% Female
    Race: 100% African American
    Intervention level: Group-level
  • Sisters Saving Sisters
    Best
    Risk category: High Risk Youth
    Sex: 100% Female
    Race: 68% African American, 32% Hispanic
    Intervention level: Group-level
  • Sister-to-Sister: Group Skills-building
    Best
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 100% African American
    Intervention level: Group-level
  • Sister-to-Sister: One-on-one Skills-building
    Best
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 100% African American
    Intervention level: Individual-level
  • Sniffer
    Good
    Risk category: Drug Users
    Sex: 70% Male, 30% Female
    Race: 51% White, 26% African American, 23% Hispanic
    Intervention level: Group-level
  • START
    Best
    Risk category: Heterosexual Adult
    Sex: 100% Male
    Race: 52% African American, 23% White, 14% Hispanic, 12% Other
    Intervention level: Individual-level
  • Street Smart
    Good
    Risk category: High Risk Youth
    Sex: 51% Male, 49% Female
    Race: 53% African American, 30% Hispanic, 16% Other
    Intervention level: Group-level
  • STRIVE
    Best
    Risk category: HCV+, Drug Users
    Sex: 76% Male, 24% Female
    Race: 57% White, 27% Hispanic, 7% African American, 10% Other
    Intervention level: Group-level
  • Teen Health Project
    Good
    Risk category: High Risk Youth
    Sex: 50% Male, 50% Female
    Race: 51% African American, 20% Asian, 20% Other, 5% White, 3% Hispanic, 1% American Indian
    Intervention level: Community-level
  • Together Learning Choices (TLC)
    Good
    Risk category: HIV+, High Risk Youth
    Sex: 72% Male, 28% Female
    Race: 37% Hispanic, 27% African American, 19% White, 17% Other
    Intervention level: Group-level
  • Treatment Advocacy Program (TAP) NEW 2014
    Best
    Risk category: HIV+, MSM
    Sex: 100% Male
    Race: 47% White, 31% African American, 17% Latino, 5% Asian/other
    Intervention level: Individual-level
  • Video Opportunities for Innovative Condom Education and Safer Sex (VOICES/VOCES)
    Best
    Risk category: Heterosexual Adult
    Sex: 60% Male, 40% Female
    Race: 62% African American, 38% Hispanic
    Intervention level: Group-level
  • Women Involved in Life Learning from Other Women (WiLLOW)
    Best
    Risk category: HIV+, Heterosexual Adult
    Sex: 100% Female
    Race: 84% African American, 15% White, 1% Other
    Intervention level: Group-level
  • Women’s Co-Op
    Best
    Risk category: Heterosexual Adult, Drug Users
    Sex: 100% Female
    Race: 100% African American
    Intervention level: Group-level
  • Women's Health Promotion (WHP)
    Best
    Risk category: Heterosexual Adult
    Sex: 100% Female
    Race: 100% Hispanic
    Intervention level: Group-level

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