CDC supports the vaccine development goals of the Global Alliance for Vaccines and Immunization (GAVI), the International AIDS Vaccine Initiative, the DHHS Blueprint for TB Vaccine Development, and the Malaria Vaccine Initiative. Over the next 5 years, CDC will work with public and private partners to help develop:

• A multistage vaccine against malaria, as part of the Malaria Vaccine Initiative, funded by the Bill and Melinda Gates Children's Vaccine Program

• A DNA-based vaccine against HIV/AIDS, in collaboration with the Emory Vaccine Center in Atlanta, Georgia

• Strain-specific vaccines against dengue and dengue hemorrhagic fever, in collaboration with Mahidol University in Salaya, Nakhonpathom, Thailand

• Conjugate vaccines against meningococcal meningitis group A, in collaboration with WHO and the Bill and Melinda Gates Children's Vaccine Program

• An Ebola vaccine, in collaboration with NIH

• Third generation vaccines against Streptococcus pneumoniae using proteins common to all pneumococcal serotypes. (Second generation conjugate vaccines are currently under evaluation [see Box 18].)

CDC vaccine researcher working in a biosafety level 4 (BSL-4) containment facility. BSL-4 laboratories are used for work on infectious agents for which there are no current vaccines or treatments (e.g., Ebola virus).