Promote Effective Drug Use
for Priority Area 4
- Conduct implementation research and demonstration projects to promote
the use of therapeutic drugs such as
- Ivermectin to eliminate onchocerchiasis in West Africa and Central
- Diethylcarbamazine and albendazole or mebendazole therapy to
eliminate lymphatic filariasis in the Americas
- Single-dose azithromycin to eliminate blinding trachoma in endemic
regions in Africa, Middle East, Asia, and Central America
- Single-dose nevirapine to prevent perinatal HIV transmission.
(See also Priority Area 5.)
- Praziquantel to treat schistosomiasis
- Promote the widespread use of the directly observed therapy shortcourse
strategy (DOTS) to treat TB. (See also Priority
- Use CDC resources to strengthen routine immunization services and
to encourage the introduction of new and underutilized vaccines, including
vaccines against hepatitis B, yellow fever, Haemophilus influenzae
type b, and other childhood diseases. (See also Priority
Promote the Use of Proven Disease Prevention Strategies
Work with private and public sector partners to promote widespread implementation
of CDCs Safe Water System,
which uses point-of-use disinfection and safe water storage to prevent
cholera, dysentery, and other waterborne diseases (Box 20).
- Work with WHO and ministries of health in central African countries
to provide training in hospital barrier nursing practices that prevent
nosocomial spread of viral hemorrhagic fevers like Ebola and Marburg.
- Continue to support the Safe Injection Global Network (SIGN) and
work with development agencies and other partners to promote safe injection
practices to prevent the spread of hepatitis B and C, HIV/AIDS, and
other bloodborne diseases.
- Work with the Roll Back Malaria partnership to promote the use of
insecticide-impregnated bednets for the prevention of malaria and other
mosquitoborne diseases. (See Priority Area
- Work with ministries of health and WHO to provide public health education
and mobilize communities to use proven public health tools.
Disseminate Diagnostic Tests
- Work through the WHO Collaborating Centre laboratory network to provide
proven diagnostic reagents for the detection of endemic diseases to
national public health laboratories and regional surveillance networks.
(See Priority Area 1.)
- Work with WHO and donor agencies to provide national public health
laboratories with state-of-the-art laboratory tests that measure antimicrobial
resistance in Mycobacterium tuberculosis and other common bacterial
pathogens, as well as in malaria parasites and in the AIDS virus. (See
Priority Area 5.)
- Work with ministries of health to transfer technology for molecular
subtyping of common bacterial pathogens (e.g., PulseNet techniques;
see Objectives for Priority
Area 2) to national public health laboratories for use in detecting
outbreaks of foodborne diseases).
Use Surveillance Data To Direct Public Health Policy
- Work with ministries of health and ministries of finance, WHO, and
- Conduct disease surveillance to assess national public health
needs and recommend specific public health tools to address them.
- Demonstrate the use of specific surveillance methods for detecting
outbreaks, for evaluating public health programs, and for driving
public health decisionmaking.
- Work with global partners to evaluate the progress of global initiatives
to combat malaria, TB, AIDS, and vaccine-preventable diseases. (See
Priority Area 5.)
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