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Global Health Programs: Malaria


The Centers for Disease Control and Prevention (CDC) works globally, including within the United States, to prevent, control, and ultimately eradicate malaria — a disease estimated by the World Health Organization to have caused more than 660,000 deaths in 2010, mostly in young children in sub-Saharan Africa.

Program Description

Where We Work

  • Angola
  • Benin
  • Bolivia
  • Brazil
  • Burma
  • Cambodia
  • Colombia
  • Democratic Republic of the Congo
  • Ecuador
  • Ethiopia
  • Ghana
  • Guatemala
  • Guinea
  • Guyana
  • Haiti
  • Honduras
  • India
  • Indonesia
  • Kenya
  • Liberia
  • Lao People's Democratic Republic
  • Madagascar
  • Malawi
  • Mali
  • Mozambique
  • Nicaragua
  • Nigeria
  • People's Republic of China
  • Peru
  • Rwanda
  • Senegal
  • Sierra Leone
  • Suriname
  • Switzerland
  • Tanzania
  • Thailand
  • Togo
  • Uganda
  • United States of America
  • Vietnam
  • Zambia
  • Zimbabwe

CDC provides scientific leadership in fighting malaria globally. Its scientists provide expertise to forge evidence-based policies and programs, develop critical scientific innovations to help guide the agenda for future public health efforts, and monitor and evaluate progress toward global malaria goals. These activities are conducted in the field in malaria-endemic countries with Ministry of Health colleagues, both to inform local policy and to share information with the global malaria community. CDC is charged by the U.S. Congress (through the Lantos-Hyde Act, 2008) to take a leading role in strategic information (monitoring and evaluation, surveillance, and operations research)–advising the U.S. Malaria Coordinator on priorities for these activities and being a key implementer.

CDC is involved in two U.S. Government health initiatives that focus on malaria: the President’s Malaria Initiative (PMI) and the Amazon Malaria Initiative (AMI). PMI, an interagency initiative implemented jointly by USAID and CDC, aims to rapidly scale up malaria control interventions in high-burden focus countries in Africa and dramatically reduce malaria-related illness and death through the wide-scale deployment of prevention and control interventions. AMI, which works in Central and South America, and PMI, which also works in the Greater Mekong subregion, contribute critical information about how we can monitor antimalarial drug resistance and prevent and control the spread of multidrug-resistant malaria so that successes achieved in PMI and other efforts are not lost or reversed. These are part of the Global Health Initiative, a conceptual framework for the administration’s global health efforts.

Public Health Impact

PMI, along with its global malaria partners, has seen all-cause mortality in children under five years fall in 12 of its initial 15 target countries where paired nationwide household surveys were conducted (2004-2006, 2007-2009, 2010-2011). Reductions range from 16 percent (Malawi) to 50 percent (Rwanda). Although multiple factors may be influencing this decline, there is evidence that the scale-up of malaria interventions has played a major role in these reductions. The World Malaria Report 2012 estimates that global malaria efforts have averted more than 1.1 million malaria-related deaths in the last decade.

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  • Page last reviewed: April 8, 2013
  • Page last updated: April 8, 2013
  • Content source: Global Health
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