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Genomics & Health Impact Update

Volume 31   Number 19   November 14 - 21, 2013About the Update

 

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Funding Opportunities

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Reports and Publications


Ethics, Policy and Law

Genomics in Practice

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Physician’s guide to hereditary angioedema : HAE is an autosomal dominant disease characterized by painful, unpredictable, recurrent attacks of inflammation affecting the hands, feet, face, abdomen, urogenital tract, and the larynx- from the National Organization for Rare Disorders

Familial hypercholesterolemia: An under-recognized but significant concern in cardiology practice.
Foody JM. Clin Cardiol. 2013 Nov 5.

Tailoring genetic/genomic services and information to the individual
Clancy T & Morgan R Nurs Stand 2013 Nov;28(10):37-43

Pharmacogenomics

a pharmacist helping a woman

Pharmacogenetic tests yield bonus benefit: better drug adherence, by  Elie Dolgin, Nature Medicine News, Nov 7

Reviews & Commentaries on Science & Technology

stacked papers

Telltale hearts. Each year, tens of thousands of young people worldwide die suddenly after their hearts stop beating for no apparent reason. Genetic testing for inherited heart rhythm disorders AKA 'molecular autopsies' are rarely performed.
Jeanne Erdmann. Nature Medicine, Nov 8

Extensive variation in chromatin states across humans
Maya Kasowski et al, Science, Nov 8

Genetics driving epigenetics.
Terrence S. Furey et al. Science, Nov 8

Genome-wide consequences of deleting any single gene
Teng X, et al. Molecular Cell, 2013 Nov 7

The vicious cycle of under-valued cancer biomarkers. Could sweeping changes bring more tests into clinical practice?
Genna Rollins,  American Association for Clinical Chemistry, Nov 2013

Blog post:  One person, many genomes, by Tom Insel, NIMH Director, Nov 2013

First director named for NHGRI's new Division of Genomics and Society, NIH News, Nov 14

NextCODE Health Mines deCODE's data, and more, to catalyze clinical diagnosis, by Ricki Lewis, DNA Science Blog, Nov 14

When causal disease alleles don't cause disease (or is that the norm?) By Anne Buchanan, The Mermaid's Tale, Nov 13

Can genomics blow up the clinical trial? Technology Review, Nov 12

How much bioinformatics does the new biologist need?  By Ayanna Monteverdi, mendelspod, Nov 11

Weak statistical standards implicated in scientific irreproducibility- One-quarter of studies that meet commonly used statistical cutoff may be false. Erika Check Hayden, Nature News , Nov 11

Documentary: Exosomes – the next small thing, by Alexey Bersenev, Nov 9

Receptive to replication: Do replication studies belong in top-tier journals? Nature Biotechnology, Nov 8

Heterogeneity in cancer genomics, Ewan’s Blog, Nov 7

Practicing precision medicine in cancer using genomics - Louis Staudt, Video, Nov 7

Tools and Databases

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CDC-Authored Genomics Publications

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CDC authors are indicated in bold

Standard enrichment methods for targeted next-generation sequencing in high-repeat genomic regions.
Mueller PW, Lyons J, Kerr G, Haase CP, Isett RB. Genet Med. 2013 Nov;15(11):910-1.

Hepatitis A virus: Host interactions, molecular epidemiology and evolution.
Vaughan G, Goncalves Rossi LM, Forbi JC, de Paula VS, Purdy MA, Xia G, Khudyakov YE.  Infect Genet Evol. 2013 Nov 5.

View previous CDC-authored publications

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About the Genomics & Health Impact Update

The Update includes  genomics and health impact news and publications, CDC announcements, reports, blogs, podcasts, and other products. The Update features genomic tests, family history, programs and practice, policy and legislation and public health science.  To receive the update electronically every week sign-up here.

 

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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC.  Note that some links may become invalid over time.

 



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