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Genomics & Health Impact Update

Published by the Office of Public Health Genomics (OPHG), the Update includes CDC announcements, publications, blogs and other products. The Update also includes links to genomics and health impact news and publications. The Update features genomic tests, family history, programs and practice, policy and legislation and public health science.  To receive this update electronically every week sign-up here.


Thursday, May 31, 2012       Volume 28   Number 22

Spotlight

globe- text: Sharing the Burden of Obesity

Evidence on Gene-Environment Interaction: How do we know it is there?

New Publication: Boffetta P, Winn DM, Ioannidis JP, et al. Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans. Int J Epidemiol. 2012 May 16.



Genomic Pulse

  • Between 2001 and 2010, more than 57,000 articles were published on gene-disease associations.  Gene-environment interaction was mentioned explicitly only in 17% of published abstracts, almost half of which focused on gene-drug interactions. To find out more, click here



Announcements



Topics of the Week


Cancer

Cardiovascular Disease

Genetic Testing in Practice

Policy and Legislation

Guidelines and Recommendations

Public Health Sciences

Funding in Translational Genomics

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CDC-Authored Genomics Publications


CDC authors are indicated in bold

Molecular characterization of diarrheagenic Escherichia coli from Libya
Ali MM, Mohamed ZK, Klena JD, Ahmed SF, Moussa TA, Ghenghesh KS. Am J Trop Med Hyg. 2012 May;86(5):866-71.

Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans
Boffetta P, Winn DM, Ioannidis JP, Thomas DC, Little J, Davey Smith G, Cogliano VJ, Hecht SS, Seminara D, Vineis P, Khoury MJ. Int J Epidemiol. 2012 May 16.

The Jamaican historical experience of the impact of educational interventions on sickle cell disease child mortality
Grosse SD, Atrash HK, Odame I, Amendah D, Piel FB, Williams TN. Am J Prev Med. 2012 Jun;42(6):e101-3.

Detectable clonal mosaicism and its relationship to aging and cancer
Jacobs KB, Yeager M, Zhou W, Wacholder S, Wang Z, Rodriguez-Santiago B, Hutchinson A, Deng X, Liu C, Horner MJ, Cullen M, Epstein CG, Burdett L, Dean MC, Chatterjee N, Sampson J, Chung CC, Kovaks J, Gapstur SM, Stevens VL, Teras LT, Gaudet MM, Albanes D, Weinstein SJ, Virtamo J, Taylor PR, Freedman ND, Abnet CC, Goldstein AM, Hu N, Yu K, Yuan JM, Liao L, Ding T, Qiao YL, Gao YT, Koh WP, Xiang YB, Tang ZZ, Fan JH, Aldrich MC, Amos C, Blot WJ, Bock CH, Gillanders EM, Harris CC, Haiman CA, Henderson BE, Kolonel LN, Le Marchand L, McNeill LH, Rybicki BA, Schwartz AG, Signorello LB, Spitz MR, Wiencke JK, Wrensch M, Wu X, Zanetti KA, Ziegler RG, Figueroa JD, Garcia-Closas M, Malats N, Marenne G, Prokunina-Olsson L, Baris D, Schwenn M, Johnson A, Landi MT, Goldin L, Consonni D, Bertazzi PA, Rotunno M, Rajaraman P, Andersson U, Freeman LE, Berg CD, Buring JE, Butler MA, Carreon T, Feychting M, Ahlbom A, Gaziano JM, Giles GG, Hallmans G, Hankinson SE, Hartge P, Henriksson R, Inskip PD, Johansen C, Landgren A, McKean-Cowdin R, Michaud DS, Melin BS, Peters U, Ruder AM, et al. Nat Genet. 2012 May 6.

Multilevel research and the challenges of implementing genomic medicine
Khoury MJ, Coates RJ, Fennell ML, Glasgow RE, Scheuner MT, Schully SD, Williams MS, Clauser SB. J Natl Cancer Inst Monogr. 2012 ;2012(44):112-20.

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia
Milton JN, Sebastiani P, Solovieff N, Hartley SW, Bhatnagar P, Arking DE, Dworkis DA, Casella JF, Barron-Casella E, Bean CJ, Hooper WC, Debaun MR, Garrett ME, Soldano K, Telen MJ, Ashley-Koch A, Gladwin MT, Baldwin CT, Steinberg MH, Klings ES. PLoS One. 2012 ;7(4):e34741.

HIV type 1 gag genetic diversity among antenatal clinic attendees in North Rift Valley, Kenya
Nyagaka B, Kiptoo MK, Lihana RW, Khamadi SA, Makokha EP, Kinyua JG, Mwangi J, Osman S, Lagat NJ, Muriuki J, Okoth V, Gicheru M, Ng'ang'a Z, Songok EM. AIDS Res Hum Retroviruses. 2012 May;28(5):523-6.

The prevalence of HLA-B27 in the US: data from the US National Health and Nutrition Examination Survey, 2009
Reveille JD, Hirsch R, Dillon CF, Carroll MD, Weisman MH. Arthritis Rheum. 2012 May;64(5):1407-11.

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels
Scott RA, Chu AY, Grarup N, Manning AK, Hivert MF, Shungin D, Tonjes A, Yesupriya A, Barnes D, Bouatia-Naji N, Glazer NL, Jackson AU, Kutalik Z, Lagou V, Marek D, Rasmussen-Torvik LJ, Stringham HM, Tanaka T, Aadahl M, Arking DE, Bergmann S, Boerwinkle E, Bonnycastle LL, Bornstein SR, Brunner E, Bumpstead SJ, Brage S, Carlson OD, Chen H, Chen YD, Chines PS, Collins FS, Couper DJ, Dennison EM, Dowling NF, et al. Diabetes. 2012 May;61(5):1291-6.

View previous CDC-authored publications

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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC.  Note that some links may become invalid over time.

 

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