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Genomics & Health Impact Update

Published by the Office of Public Health Genomics (OPHG), the Update offers links to genomics news and publications relevant to population health and health care. The Update highlights family health history and genomic tests, along with relevant data, policy, and legislation. Please send your comments to: genetics@cdc.gov.


Thursday, January 5, 2012       Volume 28   Number 1

Spotlight

calendar with January 1 and new years eve confetti and a blower

New CDC Feature: A New Year of Healthy Possibilities!
"Make being healthy your resolution. Stay healthy this year. Tips focus on a healthy you, family, home, community, and workplace. This includes gathering and sharing your family health history.”






Announcements



Topics


Genomic Tests

Pharmacogenomics and Clopidogrel
Nissen S. JAMA 2011;306(24):2727-2728

For more information on genomic applications in practice and prevention, please visit the GAPP Finder in the GAPP Knowledge Base and PLoS Currents Evidence on Genomic Tests.

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Family Health History

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Practice and Programs

Advancing care and awareness of sickle cell disease, The Washington Post, December 27

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Policy and Legislation

A push to tie new drugs to testing, The New York Times, December 26

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Public Health Science

Balancing the Risks and Benefits of Genomic Data Sharing: Genome Research Participants' Perspectives
Oliver JM, et al. Public Health Genomics 2011 Dec

Biomarker classifiers for identifying susceptible subpopulations for treatment decisions
Lin WJ, Chen JJ. Pharmacogenomics. 2011 Dec 21.​‌

Evaluating Phenotypic Data Elements for Genetics and Epidemiological Research: Experiences from the eMERGE and PhenX Network Projects
Pathak J, et al. AMIA Summits Transl Sci Proc 2011;2011:41-5

Gene-Environment Interactions in Genome-Wide Association Studies: A Comparative Study of Tests Applied to Empirical Studies of Type 2 Diabetes.
Cornelis MC, Tchetgen  EJ, Liang L, et al. Am J Epidemiol. 2011 Dec 22.

Genetics of late-onset Alzheimer's disease: update from the alzgene database and  analysis of shared pathways
Olgiati P, et al. Int J Alzheimers Dis 2011;2011:832379

Informed Choice in Direct-to-Consumer Genetic Testing (DTCGT) Websites: A Content Analysis of Benefits, Risks, and Limitations
Singleton A, et al. J Genet Couns 2011 Dec

Perceptions About Genetic Testing for the Susceptibility to Alcohol Dependence and Other Multifactorial Diseases
Marshall VJ, et al. Genet Test Mol Biomarkers 2011 Dec

The vaccine adverse event reporting system and vaccine safety research in the genomics era.
Davis RL. Vaccine. 2011 Dec 14.

Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG).
Jin G, Lu L, Cooney KA, Ray AM, et al. Hum Genet. 2011 Dec 25.

CHEK2*1100delC homozygosity is associated with a high breast cancer risk in women.
Adank MA, Jonker MA, Kluijt I, et al. J Med Genet. 2011 Dec;48(12):860-3. Epub 2011 Nov 5.

Recurrent Somatic DICER1 Mutations in Nonepithelial Ovarian Cancers.
Heravi-Moussavi A, Anglesio MS, Cheng SW, et al. N Engl J Med. 2011 Dec 21.

Gene links rare and unrelated cancers, Medical News Today, January 2

281 human genome epidemiology articles have recently been added, please visit the HuGE Literature Finder in the HuGE Navigator.

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Let's Go Surfing

Are diabetes and colorectal cancer risk genetically linked? Medscape, January 3 [by free subscription only]

Whole genome sequences of a male and female supercentenarian, ages greater than 114 years
Sebastiani P, Riva A, Montano M, et al. Front. Gene. 2012 Jan 3; 2:90.

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Events and Training


Molecular Med Tri Con 2012

The 2nd National Conference on Blood Disorders In Public Health

The Conference of the Global Sickle Cell Disease Network

Access other events

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Send Web sites that you would like to see included in a future update to genetics@cdc.gov

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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC.  Note that some links may become invalid over time.

 

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