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Genomics & Health Impact Update

The Office of Public Health Genomics (OPHG) provides updated and credible information on how genomic information and family health history can improve health and influence policy and practice. We highlight news and information on the use of genomic tests and other applications, including family health history, in clinical and public health practice and programs, along with relevant data, policy, and legislation. We hope the update is informative  to practitioners, policy makers, consumers, and researchers. Please send your comments to:

Thursday, September 15, 2011       Volume 27   Number 11


Miilion Hearts

Million Hearts is a national initiative to prevent 1 million heart attacks and strokes over the next five years

Find out more about genomics and heart disease:



Genomic Tests

For more information on genomic applications in practice and prevention, please visit the GAPP Finder in the GAPP Knowledge Base and PLoS Currents Evidence on Genomic Tests.

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Practice and Programs

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Policy and Legislation

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Public Health Science

Thrombomodulin Gene Variants Are Associated With Increased Mortality After Coronary Artery Bypass Surgery in Replicated Analyses.
R. L. Lobato, W. D. White, J. P. Mathew, et al. Circulation, 2011; 124 (11_suppl_1): S143

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma
Ferreira M.A.R. et al. Lancet 2011;378(9795):1006

Earlier age of onset of BRCA mutation-related cancers in subsequent generations
Litton J, Ready K, Chen H, et al. Cancer 2011 Sep 12

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
The International Consortium for Blood Pressure Genome-Wide Association Studies. Nature 2011 Sep 11

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
Wain LV, Verwoert GC, O'Reilly PF, et al. Nat Genet. 2011 Sep 11.

Exciting advances in cardiovascular genomics, Medscape, September 11 [by free subscription only]

160 human genome epidemiology articles have recently been added, please visit the HuGE Literature Finder in the HuGE Navigator.

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CDC-Authored Genomics Publications

CDC authors are indicated in bold

Identifying host genetic risk factors in the context of public health surveillance for invasive pneumococcal disease
Lingappa JR, Dumitrescu L, Zimmer SM, Lynfield R, McNicholl JM, Messonnier NE, Whitney CG, Crawford DC.
PLoS One. 2011 ;6(8):e23413.

IRon Overload screeNing tool (IRON): development of a tool to guide screening in primary care
Mainous AG, Diaz VA, Everett CJ, Knoll ME, Hulihan MM, Grant AM, McLaren CE, McLaren GD. Am J Hematol. 2011 Sep;86(9):733-7.

View previous CDC-authored publications

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Let's Go Surfing

Safety through genomics, Genome Web, September [by free subscription only]

Take the 'Talking Glossary of Genetic terms' mobile app with you, NHGRI, September 12

Personalized Medicine Day in Georgia, Emory Health Now Blog, September 9

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Events and Training

Beyond the Genome 2011

Next-Gen 101: A How-To for Whole-Exome Sequencing Research

24th Annual International Society of Nurses in Genetics

Access other events

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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC.  Note that some links may become invalid over time.


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  • Additional information for Public Health Genomics is available on our contact page. The U.S. Government's Official Web PortalDepartment of Health and Human Services
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