Genomics & Health Impact Update
Published by the Office of Public Health Genomics (OPHG), the Update offers links to genomics news and publications relevant to public health. The Update highlights family health history and genomic tests, along with relevant data, policy, and legislation. Please send your comments to: email@example.com.
Wednesday, November 23, 2011 Volume 27 Number 21
Family History Awareness in November
The U.S. Surgeon General declares Thanksgiving as national “Family Health History Day”, encouraging Americans to share a meal and their family health history. Family health history information can help health care providers determine which tests and screenings are recommended to help family members know their health risk.
- Learn more about family health history. Send an ecard.
- Access the Surgeon General's family history collection tool: My Family Health Portrait.
- Read more on gathering and sharing your family health history.
- Document Your Family's Health History.
- A New Publication: Beyond Base Pairs to Bedside: A Population Perspective on How Genomics Can Improve Health. Khoury M, Gwinn M, Bowen M, Dotson W. Am J Public Health. 2011 Nov 17.
- A New Publication: A Public Health Framework for Rare Blood Disorders [PDF 60.53 KB]. Grosse S, James A, Lloyd-Puryear M, et al. Am J Prev Med. 2011 41(6) Dec Suppl.
- Integrating Large-Scale Genomic Information into Clinical Practice: Workshop Summary
- Blog post "Can We Have Our Genome And Eat It Too? Deploying The Whole Genome Sequence In Medicine And Public Health, One Base Pair At A Time"
- November is Diabetes Awareness Month:
Diagnostic Accuracy of Noninvasive Detection of Fetal Trisomy 21 in Maternal Blood: A Systematic Review
Verweij EJ, et al. Fetal Diagn Ther 2011 Nov
PS1-30: Cost-Effectiveness Analysis of Screening for Kras and Braf Genetic Mutations in Metastatic Colorectal Cancer
Behl A Clin Med Res 2011 Nov;9(3-4):174
PS2-29: KRAS Testing in Metastatic Colorectal Cancer: The CERGEN-C Comparative Effectiveness Study
Pawloski P Clin Med Res 2011 Nov;9(3-4):150
Family history of liver cancer and hepatocellular carcinoma
Turati F, et al. Hepatology 2011 Nov
Parenting Through Genetic Uncertainty: Themes in the Disclosure of Breast Cancer Risk Information to Children
Sharff ME, et al. Genet Test Mol Biomarkers 2011 Nov
Take time to get medical history, Times Union, November 18
C-A3-01: Current Use of KRAS Testing in Clinical Practice
Somkin C, et al. Clin Med Res 2011 Nov;9(3-4):178
Direct-to-consumer testing: more risks than opportunities
Lippi G, et al. Int J Clin Pract 2011 Dec;65(12):1221-9
E-genetics: Exploring the acceptability and feasibility of using technology in cancer genetics services
Hilgart J, et al. Clin Genet 2011 Nov
Genomics and individuals in public health practice: are we luddites or can we meet the challenge?
Zimmern RL J Public Health (Oxf) 2011 Dec;33(4):477-82
Impact of national guidelines on family history breast cancer surveillance
Saldanha JD, et al. Scott Med J 2011 Nov;56(4):203-5
The introduction of a choice to learn presymptomatic DNA-test results for BRCA or Lynch syndrome either face-to-face or by letter
Voorwinden JS, et al. Clin Genet 2011 Nov
Personalizing medicine with clinical pharmacogenetics
Scott SA Genet Med 2011 Nov
PS2-39: Demographic Characteristics & Follow-Up Care of Patients Tested for BRCA Mutations
Strauss J, et al. Clin Med Res 2011 Nov;9(3-4):144
Gene expression profiling in breast cancer: classification, prognostication, and prediction
Reis-Filho J, Pusztai L. Lancet 2011; 378(9802):1812-1823
Breast cancer genetic profiling has not achieved personalized medicine yet, Medical News Today, November 20
New guidance for sickle cell and thalassaemia screening, PHG Foundation, November 20
Experts call for privacy on personal genetic testing, The Irish Times, November 21
C-A3-04: The Kaiser Permanente Research Program on Genes, Environment and Health: A Resource for Genetic Epidemiology in Adult Health and Aging
Schaefer C Clin Med Res 2011 Nov;9(3-4):177-8
The impact of the 21-gene recurrence score assay on decision making about adjuvant chemotherapy in early-stage estrogen-receptor-positive breast cancer in an oncology practice with a unified treatment policy.
Geffen DB, Abu-Ghanem S, Sion-Vardy N, et al. Ann Oncol. 2011 Nov;22(11):2381-6.
The impact of the 21-gene recurrence score assay on decision making about adjuvant chemotherapy in early-stage estrogen-receptor-positive breast cancer in an oncology practice with a unified treatment policy, Medscape, November 21 [by free subscription only]
Population Composition, Public Policy, and the Genetics of Smoking.
Boardman JD, Blalock CL, Pampel FC, et al. Demography. 2011 Aug 16.
Growing influence of genetic factors revealed by study of twin smokers, Medical News Today, November 18
Transient ischemic attacks characterized by RNA profiles in blood.
Zhan X, Jickling GC, Tian Y, et al. Neurology. 2011 Nov 8;77(19):1718-24.
A Biomarker for TIA? Medscape, November 17 [by free subscription only]
CDC authors are indicated in bold
Characterization of toxigenic Vibrio cholerae from Haiti, 2010-2011
Talkington D, Bopp C, Tarr C, Parsons MB, Dahourou G, Freeman M, Joyce K, Turnsek M, Garrett N, Humphrys M, Gomez G, Stroika S, Boncy J, Ochieng B, Oundo J, Klena J, Smith A, Keddy K, Gerner-Smidt P.
Emerg Infect Dis. 2011 ;17(11):2122-2129.
Comparative genomics of Vibrio cholerae from Haiti, Asia, and Africa
Reimer AR, Van Domselaar G, Stroika S, Walker M, Kent H, Tarr C, Talkington D, Rowe L, Olsen-Rasmussen M, Frace M, Sammons S, Dahourou GA, Boncy J, Smith AM, Mabon P, Petkau A, Graham M, Gilmour MW, Gerner-Smidt P. Emerg Infect Dis. 2011 ;17(11):2113-2121.
Drug-resistance mechanisms in Vibrio cholerae O1 outbreak strain, Haiti, 2010
Sjolund-Karlsson M, Reimer A, Folster JP, Walker M, Dahourou GA, Batra DG, Martin I, Joyce K, Parsons MB, Boncy J, Whichard JM, Gilmour MW. Emerg Infect Dis. 2011 ;17(11):2151-2154.
Genetic analysis and antigenic characterization of swine origin influenza viruses isolated from humans in the United States, 1990-2010
Shu B, Garten R, Emery S, Balish A, Cooper L, Sessions W, Deyde V, Smith C, Berman L, Klimov A, Lindstrom S, Xu X. Virology. 2011 Nov 10.
Influenza B viruses with mutation in the neuraminidase active site, North Carolina, USA, 2010-11
Sleeman K, Sheu TG, Moore Z, Kilpatrick S, Garg S, Fry AM, Gubareva LV. Emerg Infect Dis. 2011 November;17 (11):2043-2046.
Request For Information- Defining a Research Agenda for Sudden Cardiac Death in the Young
Thousands of British patients take part in landmark cancer-gene study, Fox News, November 21
Facts about the Human Genome Project, Penn Live, November 20
How about a pill with your name on it? Forbes, November 18
NCI wants cancer MDx validation studies, Genome Web, November 18 [by free subscription only]
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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC. Note that some links may become invalid over time.
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