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Genomics & Health Impact Update

The Office of Public Health Genomics (OPHG) provides updated and credible information on how genomic information and family health history can improve health and influence policy and practice. We highlight news and information on the use of genomic tests and other applications, including family health history, in clinical and public health practice and programs, along with relevant data, policy, and legislation. We hope the update is informative  to practitioners, policy makers, consumers, and researchers. Please send your comments to:

Thursday, May 19, 2011       Volume 26   Number 20


MMWR -Ten Great Public Health Achievements - United States, 2001-2010

Newborn Screening as one of ten great public health achievements

Newborn screening is featured in this week's MMWR as one of the 10 great public health achievements in the United States in the past decade.




Genomic Tests

For more information on genomic applications in practice and prevention, please visit the GAPP Finder in the GAPP Knowledge Base.

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Family Health History

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Practice and Programs

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Policy and Legislation

FDA warns more DTC genetics firms, Genome Web, May 17 [by free subscription only]

AMP releases statement on diagnostics in drug labels, EurekAlert, May 16

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Data and Statistics

Projecting Individualized Absolute Invasive Breast Cancer Risk in Asian and Pacific Islander American Women.
Matsuno RK, Costantino JP, Ziegler RG, et al. J Natl Cancer Inst. 2011 May 11.

MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer.
Boeri M, Verri C, Conte D, et al. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3713-8.

Tobacco-Smoking-Related Differential DNA Methylation: 27K Discovery and Replication.
Breitling LP, Yang R, Korn B, et al. Am J Hum Genet. 2011 Apr 8;88(4):450-7.

For this week's human genome epidemiology articles, please visit the HuGE Literature Finder in the HuGE Navigator.

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CDC-Authored Genomics Publications

CDC authors are indicated in bold

Comparative evaluation of automated and manual commercial DNA extraction methods for detection of Francisella tularensis DNA from suspensions and spiked swabs by real-time polymerase chain reaction
Dauphin LA, Walker RE, Petersen JM, Bowen MD. Diagn Microbiol Infect Dis. 2011 May 3.

CXCL4 and CXCL10 predict risk of fatal cerebral malaria
Wilson NO, Jain V, Roberts CE, Lucchi N, Joel PK, Singh MP, Nagpal AC, Dash AP, Udhayakumar V, Singh N, Stiles JK. Dis Markers. 2011 Jan;30(1):39-49.

Deploying whole genome sequencing in clinical practice and public health: meeting the challenge one bin at a time
Berg JS, Khoury MJ, Evans JP. Genet Med. 2011 May 9.

Evaluation of a broadly protective Chlamydia-cholera combination vaccine candidate
Eko FO, Okenu DN, Singh UP, He Q, Black C, Igietseme JU. Vaccine. 2011 May 12;29(21):3802-10.

Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation
Patton TG, Dietrich G, Dolan MC, Piesman J, Carroll JA, Gilmore Jr RD. PLoS One. 2011 ;6(5):e19536.

Genome-wide copy number alterations in subtypes of invasive breast cancers in young white and African American women
Loo LW, Wang Y, Flynn EM, Lund MJ, Bowles EJ, Buist DS, Liff JM, Flagg EW, Coates RJ, Eley JW, Hsu L, Porter PL. Breast Cancer Res Treat. 2011 May;127(1):297-308.

View previous CDC-authored publications

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Let's Go Surfing

Livestock genes could protect against one of Africa's oldest animal plagues, Seed Daily, May 18

High economic impact of Human Genome Project, PHG Foundation, May 12

Research to Reality, National Cancer Institute

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Events and Training

Third Annual Consumer Genetics Conference

2011 Genetic Alliance Annual Conference: 25 Years of Innovation

GEM'11 - The 2011 International Conference on Genetic and Evolutionary Methods

Access other events

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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC.  Note that some links may become invalid over time.


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