 112 records have been added this week to the CancerGAMAdb |
Genomics & Health Impact Update
The Office of Public Health Genomics (OPHG) provides updated and credible information on how genomic information and family health history can improve health and influence policy and practice. We highlight news and information on the use of genomic tests and other applications, including family health history, in clinical and public health practice and programs, along with relevant data, policy, and legislation. We hope the update is informative to practitioners, policy makers, consumers, and researchers. Please send your comments to: genetics@cdc.gov.
Thursday, June 9, 2011 Volume 26 Number 23
Spotlight
New Blog Posts
What is Public Health Genomics? A Day in the Invisible Life of Public Health Genomics
Announcements
- The Centers for Disease Control and Prevention announces a new funding opportunity for programs to assist the adoption of evidence-based recommendations for breast cancer genomic tests and other related interventions into health practice maximizing health benefits and minimizing harm to individuals and populations.
- Articles of interest in the June 2011 issue and supplement of Journal of Clinical Lipidology
For additional information on familial hypercholesterolemia:
- Cascade Screening for Familial Hypercholesterolemia (FH), published in PLoS Currents- Evidence on Genomic Tests, May 23, 2011 Authors: Renée M. Ned, Eric. J.G. Sijbrands
- CDC Podcast on Familial Hypercholesterolemia
Topics
Practice and Programs
College of American Pathologists/American College of Medical Genetics proficiency testing for constitutional cytogenomic microarray analysis
Brothman AR, et al. Genet Med 2011 MayLong-term follow-up of children with confirmed newborn screening disorders using record linkage
Wang Y, et al. Genet Med 2011 JunPersonalized cancer genetics training for personalized medicine: Improving community-based healthcare through a genetically literate workforce
Blazer KR, et al. Genet Med 2011 MayWhy is genetic screening for autosomal dominant disorders underused in families? The case of hereditary hemorrhagic telangiectasia
Bernhardt BA, et al. Genet Med 2011 JunNICE to develop new guideline on acute painful sickle cell episode, Medical News Today, June 8
Screening for lynch syndrome in young colon cancer patients, Medscape Today, June 8
WHO grand challenges in genomics for developing countries, PHG Foundation, June 8
Geneticists' opposition to direct-to-consumer genetic tests, PHG Foundation, June 6
Policy and Legislation
Blueprint for a deliberative public forum on biobanking policy: were theoretical principles achievable in practice?
Molster C, et al. Health Expect 2011 JunEthical and practical challenges of sharing data from genome-wide association studies: The eMERGE Consortium experience
McGuire AL, et al. Genome Res 2011 JunWomen get more access, privacy with gene tests, The Tennessean, June 5
Newborn screening bill passes Assembly, SF Gate, June 2
Data and Statistics
Birth Prevalence Rates of Newborn Screening Disorders in Relation to Screening Practices in the United States
Hertzberg VS, et al. J Pediatr 2011 JunEvaluation of mailed pediatric buccal cytobrushes for use in a case-control study of birth defects
Gallagher ML, et al. Birth Defects Res A Clin Mol Teratol 2011 MayLong-Term Prognosis of Acute Myeloid Leukemia According to the New Genetic Risk Classification of the European LeukemiaNet Recommendations: Evaluation of the Proposed Reporting System
Rollig C, et al. J Clin Oncol 2011 MayMedia Coverage of Direct-to-Consumer Genetic Testing
Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism
Lynch J, et al. J Genet Couns 2011 Jun
Schmidt RJ, Hansen RL, Hartiala J, Allayee H, Schmidt LC, Tancredi DJ, Tassone F, Hertz-Picciotto I. Epidemiology. 2011 May 23.Public attitudes toward ancillary information revealed by pharmacogenetic testing under limited information conditions
Haga SB, et al. Genet Med 2011 MayComparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses
Ioannidis JP, Panagiotou OA. JAMA. 2011 Jun 1;305(21):2200-10.Highly cited biomarker studies exaggerate findings, PHG Foundation, June 7
Gene fault could predict ovarian cancer drug success, Medical News Today, June 7
Researchers report proof-of-principle findings on sequencing-based cancer gene profiling approach, Genome Web, June 7 [by free subscription only]
Clotting Factor Gene Polymorphisms and Colorectal Cancer Risk
Vossen CY, Hoffmeister M, Chang-Claude JC, et al. J Clin Oncol. 2011 May 1;29(13):1722-7.Blood clotting and bowel cancer risk, EurekAlert, June 6
Cancer Risks Associated With Germline Mutations in MLH1, MSH2, and MSH6 Genes in Lynch Syndrome
Valérie Bonadona, MD, PhD; Bernard Bonaïti, MSc; Sylviane Olschwang, MD, PhD; et al. JAMA 2011;305[22]2304-2310.Study identifies genetic mutations associated with cancer risk for hereditary cancer syndrome, Medical News Today, June 4
Transcriptomic analysis of autistic brain reveals convergent molecular pathology
Voineagu I, Wang X, Johnston P, et al. Nature. 2011 May 25Autism blurs distinctions between brain regions, NIH News, June 2
A DNA methylation fingerprint of 1,628 human samples
Fernandez AF, Assenov Y, Martin-Subero J. et al. Genome Res. 2011 May 25.Characterizing epigenetic fingerprint of 1,628 people may reveal unknown origin of metastasis and lead to improved treatments, Medical News Today, June 2
Distinguishing Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia–Associated Mutations From Background Genetic Noise
Jamie D. Kapplinger, BA, Andrew P. Landstrom, BS, Benjamin A. Salisbury, PhD, et al. J Am Coll Cardiol, 2011; 57:2317-2327Gene tests don't help detect disease of right ventricular myocardium, Medscape, June 2
For this week's 203 human genome epidemiology articles, please visit the HuGE Literature Finder in the HuGE Navigator.
CDC-Authored Genomics Publications
CDC authors are indicated in bold
Birth Prevalence Rates of Newborn Screening Disorders in Relation to Screening Practices in the United States
Hertzberg VS, Hinton CF, Therrell BL, Shapira SK. J Pediatr 2011 JunDetection of G3P[3] and G3P[9] rotavirus strains in American Indian children with evidence of gene reassortment between human and animal rotaviruses
Grant L, Esona M, Gentsch J, Watt J, Reid R, Weatherholtz R, Santosham M, Parashar U, O'Brien K. J Med Virol. 2011 Jul;83(7):1288-99.Evaluation of immunization rates and safety among children with inborn errors of metabolism
Klein NP, Aukes L, Lee J, Fireman B, Shapira SK, Slade B, Baxter R, Summar M. Pediatrics. 2011 May;127(5):e1139-46.Evaluation of mailed pediatric buccal cytobrushes for use in a case-control study of birth defects
Gallagher ML, Sturchio C, Smith A, Koontz D, Jenkins MM, Honein MA, Rasmussen SA. Birth Defects Res A Clin Mol Teratol 2011 MayToward the development of a hepatitis E vaccine
Kamili S. Virus Res. 2011 May 18.
View previous CDC-authored publications
Let's Go Surfing
High-throughput strategies identifying genetic, epigenetic changes in head and neck cancers, EurekAlert, June 6
Mutation-specific therapy in lung cancer: this is the future, Medscape, June 6
Weight loss after gastric bypass surgery reduces expression of Alzheimer's genes, Medical News Today, June 6
Major shift in war on cancer, The Wall Street Journal, June 4
Gene therapy progress for Parkinson's disease, PHG Foundation, June 3
Genome sequence identifies super-toxic bacteria as cause of the current European epidemic, Medical News Today, June 3
Matching targeted therapies to tumor's specific gene mutations key to personalized cancer treatment, EurekAlert, June 3
Wielding genomes in the fight against cancer, The New York Times, June 3
Computing personal genomics, HPC, June 2
Events and Training
Joining FORCEs 2011 conference
Human Genome Analysis: Genetic Analysis of Multifactorial Diseases
British Human Genetics Conference 2011
Send Web sites that you would like to see included in a future update to cdcinfo@cdc.gov
Sign-up for new Genomics and Health Impact Updates through GovDelivery.
You may return to GovDelivery to edit preferences.
The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC. Note that some links may become invalid over time.
Get email updates
To receive the impact update electronically every week, enter your email address:
Contact Us:
- CDC-INFO Contact Center
Phone: 800-232-4636 (800-CDC-INFO)
Hearing Impaired: 888-232-6348 - cdcinfo@cdc.gov
- Additional information for Public Health Genomics is available on our contact page.
