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Genomics & Health Impact Update

The Office of Public Health Genomics (OPHG) provides updated and credible information on how genomic information and family health history can improve health and influence policy and practice. We highlight news and information on the use of genomic tests and other applications, including family health history, in clinical and public health practice and programs, along with relevant data, policy, and legislation. We hope the update is informative  to practitioners, policy makers, consumers, and researchers. Please send your comments to:

Thursday, July 14, 2011       Volume 27   Number 2


blue helix

CDC has issued a Request for Information (RFI) [PDF 185.98 KB] for comments, data, and other information helpful to assess the current research, policy, and practice environment in public health genomics, as part of a process to assess the most important steps for the field in the next five years. Submit comments in response to the RFI here.



Family Health History

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Practice and Programs

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Data and Statistics

Systems biology of vaccination for seasonal influenza in humans.
Nakaya HI, Wrammert J, Lee EK, et al. Nat Immunol. 2011 Jul 10

199 human genome epidemiology articles have recently been added, please visit the HuGE Literature Finder in the HuGE Navigator.

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CDC-Authored Genomics Publications

CDC authors are indicated in bold

The contribution of chromosomal abnormalities to congenital heart defects: a population-based study
Hartman RJ, Rasmussen SA, Botto LD, Riehle-Colarusso T, Martin CL, Cragan JD, Shin M, Correa A. Pediatr Cardiol. 2011 Jul 5.

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-kappaB signaling pathways
Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP. Immunity. 2011 Jun 24;34(6):854-65.

Palliative care services in families of males with Duchenne muscular dystrophy
Arias R, Andrews J, Pandya S, Pettit K, Trout C, Apkon S, Karwoski J, Cunniff C, Matthews D, Miller T, Davis MF, Meaney FJ. Muscle Nerve. 2011 Jul;44(1):93-101.

Subtype analysis of Cryptosporidium parvum and Cryptosporidium hominis isolates from humans and cattle in Iran
Nazemalhosseini-Mojarad E, Haghighi A, Taghipour N, Keshavarz A, Mohebi SR, Zali MR, Xiao L. Vet Parasitol. 2011 Jun 30;179(1-3):250-2.

Toll-like and adenosine receptor expression in injured skeletal muscle
Warren GL, Hulderman T, Liston A, Simeonova PP. Muscle Nerve. 2011 Jul;44(1):85-92.

View previous CDC-authored publications

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Let's Go Surfing

Increased exonic de novo mutation rate in individuals with schizophrenia.
Simon L Girard, Julie Gauthier, Anne Noreau, et al. Nature Genetics, 2011

Update on the pharmacogenomics of proton pump inhibitors
Krisztina Hagymási; Katalin Müllner; László Herszényi; et al. Pharmacogenomics. 2011;12(6):873-888.

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Events and Training

Cancer Nanotechnology

Human Genetics & Genomics

7th ISNS European Neonatal Screening Regional Meeting

Access other events

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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC.  Note that some links may become invalid over time.


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