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Genomics & Health Impact Update

2012 happy new year balloonsPublished by the Office of Public Health Genomics (OPHG), the Update offers links to genomics news and publications relevant to population health and health care. The Update highlights family health history and genomic tests, along with relevant data, policy, and legislation. Please send your comments to: genetics@cdc.gov.


Thursday, December 22, 2011       Volume 27   Number 25

Spotlight

photo  of a family

New CDC Feature: Gather and Share Your Family Health History

Blog Post: Family Health History and the Holidays

Access the Surgeon General's Family History Collection tool: My Family Health Portrait.






Announcements



Topics


Genomic Tests

Clinical utility gene card for: acrodermatitis enteropathica
Kury S, et al. Eur J Hum Genet 2011 Dec

Clinical utility gene card for: Alport syndrome
Hertz JM, et al. Eur J Hum Genet 2011 Dec

Validation of warfarin pharmacogenetic algorithms in clinical practice
Marin-Leblanc M, et al. Pharmacogenomics 2012 Jan;13(1):21-9

Human papillomavirus testing for the detection of high-grade cervical intraepithelial neoplasia and cancer: final results of the POBASCAM randomised controlled trial
Rijkaart D, Berkhof J, Rozendaal L, et al. The Lancet Oncology, Early Online Publication, 15 December 2011

HPV DNA Testing advised for females over 30, Medical News Today, December 15

For more information on genomic applications in practice and prevention, please visit the GAPP Finder in the GAPP Knowledge Base and PLoS Currents Evidence on Genomic Tests.

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Family Health History

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Practice and Programs

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Policy and Legislation

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Public Health Science

The evolution of drug resistance, The Scientist, December 18

170 human genome epidemiology articles have recently been added, please visit the HuGE Literature Finder in the HuGE Navigator.

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CDC-Authored Genomics Publications


CDC authors are indicated in bold

Accuracy of self-reported family history is strongly influenced by the accuracy of self-reported personal health status of relatives
Janssens AC, Henneman L, Detmar SB, Khoury MJ, Steyerberg EW, Eijkemans MJ, Mushkudiani N, Oostra BA, van Duijn CM, Mackenbach JP. J Clin Epidemiol. 2012 Jan;65(1):82-9.

Family history of colorectal cancer: clinicians' preventive recommendations and patient behavior
Zlot AI, Silvey K, Newell N, Leman R, Coates RJ. Prev Chronic Dis 2012 Jan;9:E2

Genetic associations with metabolic syndrome and its quantitative traits by race/ethnicity in the United States
Vassy JL, Shrader P, Yang QLiu T, Yesupriya A, Chang MH, Dowling NF, Ned RM, Dupuis J, Florez JC, Khoury MJ, Meigs JB. Metab Syndr Relat Disord. 2011 Dec;9(6):475-82.

A Pilot Study of Host Genetic Variants Associated with Influenza-associated Deaths among Children and Young Adults
Jill M. Ferdinands , Amy M. Denison, Nicole F. Dowling, Heather A. Jost, Marta L. Gwinn, Lindy Liu, Sherif R. Zaki, and David K. Shay Emerging Infectious Diseases 2011 17(12) Dec

Restricted enzooticity of hepatitis E virus genotypes 1 to 4 in the United States
Dong C, Meng J, Dai X, Liang JH, Feagins AR, Meng XJ, Belfiore NM, Bradford C, Corn JL, Cray C, Glass GE, Gordon ML, Hesse RA, Montgomery DL, Nicholson WL, Pilny AA, Ramamoorthy S, Shaver DD, Drobeniuc J, Purdy MA, Fields HA, Kamili S, Teo CG. J Clin Microbiol. 2011 Dec;49(12):4164-72.

Use of family history in clinical guidelines for diabetes and colorectal cancer
Peterson BA, Gwinn ML, Valdez RA. Am J Prev Med 2012 Jan;42(1):65-70

View previous CDC-authored publications

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Let's Go Surfing

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Events and Training


Using Whole Genome Sequencing for Health

Complex Traits: Genomics and Computational Approaches

2012 Training Institute for Dissemination and Implementation Research in Health (TIDIRH)  

Access other events

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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC.  Note that some links may become invalid over time.

 

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