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Genomics & Health Impact Update

Published by the Office of Public Health Genomics (OPHG), the Update offers links to genomics news and publications relevant to population health and health care. The Update highlights family health history and genomic tests, along with relevant data, policy, and legislation. Please send your comments to:

Thursday, December 15, 2011       Volume 27   Number 24


photo  of a family

New Blog Post: Family Health History and the Holidays

Access the Surgeon General's Family History Collection tool: My Family Health Portrait.



Genomic Tests

For more information on genomic applications in practice and prevention, please visit the GAPP Finder in the GAPP Knowledge Base and PLoS Currents Evidence on Genomic Tests.

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Family Health History

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Practice and Programs

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Policy and Legislation

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Public Health Science

Genetic profile in ALL -- Should all patients be screened? Medscape, December 13 [by free subscription only]

Dissecting the Genetics of Complex Inheritance: Linkage Disequilibrium Mapping Provides Insight into Crohn's Disease
Elding H, Lau W, Swallow D, et al. American Journal of Human Genetics 2011; 89(6);798-805

Gene-environment interaction in chronic disease: A European Science Foundation Forward Look
Renz H, Autenrieth I, Brandtzæg P, et al. J Allergy Clin Immunol. 2011 128(6) Suppl;S27-S49

170 human genome epidemiology articles have recently been added, please visit the HuGE Literature Finder in the HuGE Navigator.

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CDC-Authored Genomics Publications

CDC authors are indicated in bold

Development of a high-throughput microsphere-based molecular assay to identify 15 common bloodmeal hosts of Culex mosquitoes
Thiemann TC, Brault AC, Ernest HB, Reisen WK. Mol Ecol Resour. 2011 Dec 4.

Differential microRNA expression and virulence of avian, 1918 reassortant, and reconstructed 1918 influenza A viruses
Li Y, Li J, Belisle S, Baskin CR, Tumpey TM, Katze MG. Virology. 2011 Dec 20;421(2):105-13.

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials
Ledgerwood JE, Wei CJ, Hu Z, Gordon IJ, Enama ME, Hendel CS, McTamney PM, Pearce MB, Yassine HM, Boyington JC, Bailer R, Tumpey TM, Koup RA, Mascola JR, Nabel GJ, Graham BS. Lancet Infect Dis. 2011 Dec;11(12):916-924.

Iron overload what is the role of public health? 
Hulihan MM, Sayers CA, Grosse SD, Garrison C, Grant AM. Am J Prev Med. 2011 Dec;41(6 Suppl 4):S422-7.

A public health framework for rare blood disorders
Grosse SD, James AH, Lloyd-Puryear MA, Atrash HK. Am J Prev Med. 2011 Dec;41(6 Suppl 4):S319-23.

First NDM-positive Salmonella sp. strain identified in the United States
Savard P, Gopinath R, Zhu W, Kitchel B, Rasheed JK, Tekle T, Roberts A, Ross T, Razeq J, Landrum BM, Wilson LE, Limbago B, Perl TM, Carroll KC. Antimicrob Agents Chemother. 2011 Dec;55(12):5957-8.

Human T-cell lymphotropic virus type 3 (HTLV-3)- and HTLV-4-derived antisense transcripts encode proteins with similar tax-inhibiting functions but distinct subcellular localization
Larocque E, Halin M, Landry S, Marriott SJ, Switzer WM, Barbeau B. J Virol. 2011 Dec;85(23):12673-85.

Public health implications of sickle cell trait: a report of the CDC meeting
Grant AM, Parker CS, Jordan LB, Hulihan MM, Creary MS, Lloyd-Puryear MA, Goldsmith JC, Atrash HK. Am J Prev Med. 2011 Dec;41(6 Suppl 4):S435-9.

Screening U.S. college athletes for their sickle cell disease carrier status
Jordan LB, Smith-Whitley K, Treadwell MJ, Telfair J, Grant AM, Ohene-Frempong K. Am J Prev Med. 2011 Dec;41(6 Suppl 4):S406-12.

Sickle cell disease in Africa: a neglected cause of early childhood mortality
Grosse SD, Odame I, Atrash HK, Amendah DD, Piel FB, Williams TN. Am J Prev Med. 2011 Dec;41(6 Suppl 4):S398-405.

Sickle cell disease the need for a public health agenda
Yusuf HR, Lloyd-Puryear MA, Grant AM, Parker CS, Creary MS, Atrash HK. Am J Prev Med. 2011 Dec;41(6 Suppl 4):S376-83.

Trends in cytogenetic testing and identification of chromosomal abnormalities among pregnancies and children with birth defects, metropolitan Atlanta, 1968-2005
Jackson JM, Crider KS, Rasmussen SA, Cragan JD, Olney RS. Am J Med Genet A. 2011 Dec 2.

Variants in ABCB1, TGFB1, and XRCC1 genes and susceptibility to viral hepatitis A infection in Mexican Americans
Zhang L, Yesupriya A, Hu DJ, Chang MH, Dowling NF, Ned RM, Udhayakumar V, Lindegren ML, Khudyakov Y. Hepatology. 2011 Dec 2.

View previous CDC-authored publications

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Let's Go Surfing

New NHGRI projects seek to further sequencing-based medicine, Genome Web, December 9 [by free subscription only]

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Events and Training

Gene Silencing by Small RNAs

Omics and Personalised Health

Genomic Screening and Diagnosis of Human Diseases

Access other events

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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC.  Note that some links may become invalid over time.


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