Genomics & Health Weekly Update

This weekly update provides information about the impact of human genomic research on disease prevention & population health. Learn more about the Genomics & Health Weekly Update.

Thursday, October 1, 2009       Volume 23   Number 14

 

Spotlight

Breast and Ovarian Cancer Awareness in September and October
Breast cancer is the most common form of cancer in women. During an average lifetime, a woman’s risk to develop breast cancer is about 1 of 8 or 12%. Ovarian cancer is less common; affecting about 1 out of every 70 women (less than 2%) during their lifetime. Learn more about topics related to breast and ovarian cancer: the role of family health history and risk categories, genetic testing information and guidelines, and genetic counseling.

 

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Announcements

• New Web pages for the CDC-funded genomics translation project entitled Oregon Genomics Surveillance Program: Translation of Genomics Applications into Health Practice at the Oregon Department of Human Services. Visit the Web pages. Learn more about other CDC-funded translation genomics.
• Obtain free access to the August 2009 issue of Genetics in Medicine, focusing on personal genomics.

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Genomics In The News

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Autoimmune Diseases

Scientists identify genetic cause of previously undefined primary immune deficiency disease, EurekAlert, September 24

Symposium on genetics of psoriasis and psoriatic arthritis to be held, News-Medical.Net, September 24

Cancer

Lung cancer risk increases with expression of specific genes, EurekAlert, October 1

Bowel cancer gene discovery, Yahoo News, September 30

NCI and NHGRI collaborate to characterize genetic and genomic changes that occur in cancers, News-Medical.Net, September 30

UCSD takes lead in landmark study of breast cancer, Sign on San Diego, September 30

Genetic testing helps sisters in fight against cancer, The News-Gazette.com, September 29

New genetic variants for prostate cancer susceptibility, PHG Foundation, September 28

New cancer drug test promises safer and more effective clinical trials, Science Daily, September 24

Ethical, Legal, and Social Issues (ELSI)

Sharing genetic data may lead to better treatments, Deseret News, October 1

Stakes rise in gene-patenting lawsuit: Hearing today pits AMA, other heavyweights, against the U., Myriad Genetics and the patents office, Trading Markets, September 30

Doctors told to warn patients of their genetic risks, Medical News Today, September 29

Guidance on patient confidentiality and genetic diseases, PHG Foundation, September 29

How to deliver the news? New advice for doctors diagnosing prenatal Down syndrome, EurekAlert, September 28

Family History

Your family's medical history could affect your care, lifestyle, Star-Telegram, September 25

Genetic Testing

Gene tests rate sudden cardiac death risk, CBS News, September 30

Don't skip newborn screening, The Baltimore Sun, September 29

Ohio State joins huge genetic screening study, The Columbus Dispatch, September 29

New DNA test predicts risk of severe scoliosis, Health News Digest, September 24

Influenza

CDC again cautions against using rapid flu tests for H1N1 detection, Genome Web, September 25

Mental Health

Study of genes, toxic metals in children with autism spectrum disorders launched by UT Houston, Jamaica researchers, Medical News Today, October 1

Wayne State University to lead first ever combined imaging and genetics study in childhood OCD, Medical News Today, September 29

Improving the accuracy of predicting violent behaviour may alleviate negative effects of violence, News-Medical.Net, September 28

Schizophrenia gene linked with abnormal neurogenesis in adult and postnatal brain, Science Daily, September 24

Other News

$16.8 million NIH grant received by Johns Hopkins Epigenetic center, Medical News Today, September 30

UNC awarded Cancer Genome Atlas grant, EurekAlert, September 30

NIH funds Brown University's Samoan genotyping project, News-Medical.Net, September 28

NIH funds four centers of excellence in genomic science, NIH News, September 28

C. difficile hypervirulence genes identified, Medical News Today, September 26

Haussler and Kent honored by American Society of Human Genetics, UCSC News, September 25

Genome Standards Consortium evolves and expands to keep pace with rapid advances in the field, Genome Web, September 24 [by free subscription only]

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Genomics in Scientific Literature

 

Family History

The Family Atherosclerosis Monitoring In earLY life (FAMILY) study: rationale, design, and baseline data of a study examining the early determinants of atherosclerosis
Morrison KM, et al.
Am Heart J 2009 Oct;158(4):533-9

Family history of myocardial infarction predicts incident coronary heart disease  in postmenopausal women with diabetes: the Women's Health Initiative Observational Study
Li R, et al.
Diabetes Metab Res Rev 2009 Sep

Genotype to Phenotype: Analyzing the Effects of Inherited Mutations in Colorectal Cancer Families
Heinen CD
Mutat Res 2009 Sep

Genetic Testing

Cancer risk assessment by rural and Appalachian family medicine physicians
Kelly KM, et al.
J Rural Health 2009 Fall;25(4):372-7

Development and Characterization of Reference Materials for MTHFR, SERPINA1, RET, BRCA1, and BRCA2 Genetic Testing
Barker SD, et al.
J Mol Diagn 2009 Sep

Genome Wide

Genomewide Association Study for Onset Age in Parkinson Disease
Latourelle JC, et al.
BMC Med Genet 2009 Sep;10(1):98

A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1
Nakanishi H, et al.
PLoS Genet 2009 Sep;5(9):e1000660

Pharmacogenomics

UGT1A1 genotyping: a predictor of irinotecan-associated side effects and drug efficacy?
Schulz C, et al.
Anticancer Drugs 2009 Sep

Pharmacogenomic variations in treatment protocols for childhood acute lymphoblastic leukemia
Yang YL, et al.
Pediatr Blood Cancer 2009 Sep

General Articles

Endothelial nitric oxide synthase gene polymorphisms and diabetic nephropathy: A  HuGE review and meta-analysis
Zintzaras E et al.
Genet Med 2009 Sep

Genetic basis of neural tube defects
Bassuk AG & Kibar Z
Semin Pediatr Neurol 2009 Sep;16(3):101-10

The potential for automated question answering in the context of genomic medicine: an assessment of existing resources and properties of answers
Overby CL, et al.
BMC Bioinformatics 2009;10 Suppl 9:S8

FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases
Lattka E, et al.
J Nutrigenet Nutrigenomics 2009 Sep;2(3):119-28

Views on Personalized Medicine: Do the Attitudes of African American and White Prescription Drug Consumers Differ?
De Marco M
Public Health Genomics 2009 Sep

China: Public Health Genomics
Zheng S, et al.
Public Health Genomics 2009 Sep

Rheumatoid arthritis genetics: 2009 update
Plenge RM
Curr Rheumatol Rep 2009 Oct;11(5):351-6

Are essential genes really essential?
D'Elia MA, et al.
Trends Microbiol 2009 Sep

Musings on genome medicine: the Obama effect redux
Nathan DG & Orkin SH
Genome Med 2009 Sep;1(9):86

Developments in Genomics to Improve Understanding, Diagnosis and Management of Aneurysms and Peripheral Artery Disease
Tromp G & Kuivaniemi H
Eur J Vasc Endovasc Surg 2009 Sep

Perceptions of the Concept of Mutation among Family Members of Patients Receiving Outpatient Genetic Services and University Students
Ando N, et al.
J Genet Couns 2009 Sep

Recent studies on the genetic basis of ankylosing spondylitis
Reveille JD
Curr Rheumatol Rep 2009 Oct;11(5):340-8

HuGE

For this week's human genome epidemiology articles, please visit the HuGE Navigator.

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Send web sites that you would like to see included in a future update to cdcinfo@cdc.gov Sign-up for new Genomics and Health Weekly Updates through GovDelivery. You may return to GovDelivery to edit preferences. The CDC Office of Public Health Genomics makes available the above information as a public service only. Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.