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Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
 
 
 Wednesday, March 25, 2009 Volume 22   Number 12
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This weekly update provides information about the impact of human genomic research on disease prevention & population health. open mailbox for email deliveryGet email updates
Spotlight

light bulbCDC Director’s Innovation Award to be presented to Linda Bradley, PhD, and the Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Team this month. Read more.

Sections

blue dotView Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 Upcoming Events
Genomics Announcements
   
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The Institute of Medicine requests public input regarding priorities for comparative effectiveness research (CER) non-gov warning icon as called for in the American Recovery and Reinvestment Act of 2009 (Stimulus Bill). Submit your comments non-gov warning icon. Deadline: Friday, March 27th. For questions or comments, please contact: cerpriorities@nas.edu.
   
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The U.S. Equal Employment Opportunity Commission (EEOC) seeks public comment on proposed regulations implementing Genetic Information Non-Discrimination Act (GINA). Deadline: May 1, 2009. Read the press release.
 
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The Secretary's Advisory Committee on Genetics, Health, and Society (SACGHS) requests public comment on draft report on gene patents and licensing practices and their impact on patient access to genetic tests. Deadline: May 15, 2009. Read more.
 
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University of Washington Center for Genomics and Public Health hosts the 2009 Summer Institute in Public Health Genomics: Translating Genomics into Policy and Practice, non-gov warning icon  June 22- 26, 2009 in Seattle Washington. Early bird registration deadline: May 18, 2009.


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

Genetic changes outside nuclear DNA suspected to trigger more than... non-gov warning icon Medical News Today, March 25

Docs look to gene-guided prostate cancer cure, non-gov warning icon MSNBC, March 23

Human papillomavirus genotype distribution in New Mexico cervical cancers, non-gov warning icon EurekAlert, March 24

The prevalence of BRCA mutations among young women with triple-negative breast cancer, non-gov warning icon 7th Space Interactive, March 19

NYU study finds new risk factor for melanoma in younger women, non-gov warning icon EurekAlert, March 24

 
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Cardiovascular Disease

Heart: International effort finds out new genetic variants associated with QT interval, non-gov warning icon Medical News Today, March 24

Discovery of ten genes linked to sudden cardiac death, non-gov warning icon News-Medical.Net, March 22

Recently identified genetic heart disorder often deadly for young patients, non-gov warning icon EurekAlert, March 24

 

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Diabetes

Awareness: Calculator gives risk of Type 2
Diabetes
, non-gov warning icon The New York Times, March 23 

Type 2 diabetes risk differs by ethnic group, Yahoo News, March 20

 

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Ethical, Legal and Social Issues (ELSI)

NY State Regulates DTC Genetic Testing Labs, non-gov warning icon Gerson Lehrman Group, March 23

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Genetic Testing

Clinical researchers get new tool to ensure accuracy of genetic testing, non-gov warning icon Earth Times, March 24

The business of genetic testing, non-gov warning icon BBC, March 20

Family's cancer legacy moves teen to ponder genetic testing, non-gov warning icon News-Journal Online, March 22

 

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Mental Health

Researchers discover new genetic syndrome, non-gov warning icon Yale Daily News, March 25

Foundation for NIH facilitated partnership announces availability of Alzheimer's genome biomarker data, non-gov warning icon Medical News Today, March 20

Early brain marker for familial form of depression identified by Columbia researchers, non-gov warning icon Medical News Today, March 24

 

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Obesity

Obesity gene associated with susceptibility to polycystic ovary syndrome, non-gov warning icon Science Daily, March 23

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Pharmacogenomics

3 genes determine right warfarin dose, non-gov warning icon News-Medical.Net, March 22

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Smoking & Tobacco

Gene changes impact smokers' lung disease risk, non-gov warning icon Reuters Health, March 20

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Other News

Discovery of 'master regulator' gene for skin development, non-gov warning icon News-Medical.Net, March 25

Glaucoma mystery solved by genetic sleuth, non-gov warning icon Medical News Today, March 23

Genetic testing program launching in Silicon Valley, non-gov warning icon KLIV, March 24

Researchers investigate new way to block reproduction of the hepatitis C virus, non-gov warning icon News-Medical.Net, March 23

Genomic variations in African American and white populations, non-gov warning icon Medical News Today, March 24

New map of 55,000 gene enhancers broadens scientific understanding of the human..., non-gov warning icon Medical News Today, March 20

Redefining DNA: Darwin from the atom up, non-gov warning icon Medical News Today, March 24

BUSM researchers identify gene variant associated with chronic obstructive pulmonary disease, non-gov warning icon EurekAlert, March 19

   
Genomics in Scientific Literature
Featured Item

Planning the Human Variome Project: The Spain report
Kaput J, et al.
Hum Mutat 2009 Jan;30(4):496-510


 General Articles

Genes associated with idiopathic epilepsies: a current overview
Lu Y & Wang X
Neurol Res 2009 Mar;31(2):135-43

Parkinson's disease: from monogenic forms to genetic susceptibility factors
Lesage S & Brice A
Hum Mol Genet 2009 Apr;18(R1):R48-59

The genetics of chronic inflammatory diseases
Heap GA & van Heel DA
Hum Mol Genet 2009 Apr;18(R1):R101-6

Agreement among type 2 diabetes linkage studies but a poor correlation with results from genome-wide association studies
Lillioja S & Wilton A
Diabetologia 2009 Mar

Coexistent True Aortic Aneurysm as a Cause of Acute Aortic Dissection
Tamori Y, et al.
Circ J 2009 Mar

MicroRNAs and genomic variations: from Proteus tricks to Prometheus gift
Fabbri M, et al.
Carcinogenesis 2009 Mar

Pharmacogenetics: from discovery to patient care
Shin J, et al.
Am J Health Syst Pharm 2009 Apr;66(7):625-37

Decision-Making About Inherited Cancer Risk: Exploring Dimensions of Genetic Responsibility
Etchegary H, et al.
J Genet Couns 2009 Mar

Sharing data between LSDBs and central repositories
den Dunnen JT, et al.
Hum Mutat 2009 Jan;30(4):493-5

Recent advances in the genetics of autoimmune disease
Gregersen PK & Olsson LM
Annu Rev Immunol 2009;27:363-91

A consultation with genetic information about obesity decreases self-blame about  eating and leads to realistic weight loss goals in obese individuals
Conradt M, et al.
J Psychosom Res 2009 Apr;66(4):287-95

The genetics of obsessive-compulsive disorder and Tourette's syndrome: what are the common factors?
Grados MA
Curr Psychiatry Rep 2009 Apr;11(2):162-6

The genetics of reading disability
Petryshen TL & Pauls DL
Curr Psychiatry Rep 2009 Apr;11(2):149-55

Advances in genetic studies of attention-deficit/hyperactivity disorder
Smith AK, et al.
Curr Psychiatry Rep 2009 Apr;11(2):143-8

Genetics and genomic medicine
Bogaard K & Johnson M
Radiol Technol 2009 Mar-2009 Apr;80(4):318-35; quiz 336-9

Molecular genetics of atherosclerosis
Roy H, et al.
Hum Genet 2009 Mar

 

 Family History

Endometriosis related to family history of malignancies in the Yale series
Matalliotakis IM, et al.
Surg Oncol 2009 Mar

No evidence of familial correlation in breast cancer metastasis
Whittemore AS, et al.
Breast Cancer Res Treat 2009 Mar

Perceived Intrafamily Melanoma Risk Communication
Loescher LJ, et al.
Cancer Nurs 2009 Mar

Family history of affective illness in Schizophrenia patients: Symptoms and cognition
Anglin D, et al.
Schizophr Res 2009 Mar

Screening for gestational diabetes: usefulness of clinical risk factors
Shirazian N, et al.
Arch Gynecol Obstet 2009 Mar

 

 Genetic Testing

Identification and management of women at high risk for hereditary breast/ovarian cancer syndrome
Ozanne EM, et al.
Breast J 2009 Mar-2009 Apr;15(2):155-62

Newborn screening for krabbe disease: the new york state model
Duffner PK, et al.
Pediatr Neurol 2009 Apr;40(4):245-52

Genetic Testing Before Anticoagulation? A Systematic Review of Pharmacogenetic Dosing of Warfarin
Kangelaris KN, et al.
J Gen Intern Med 2009 Mar

 

 Genome Wide

A genome-wide association study of pulmonary function measures in the framingham  heart study
Wilk JB, et al.
PLoS Genet 2009 Mar;5(3):e1000429

Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations
Tanaka T, et al.
Am J Hum Genet 2009 Mar

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal  Genetic Determinants of Warfarin Dose
Takeuchi F, et al.
PLoS Genet 2009 Mar;5(3):e1000433

A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD):  Identification of Two Major Susceptibility Loci
Pillai SG, et al.
PLoS Genet 2009 Mar;5(3):e1000421

A genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility
Knight JA, et al.
Blood 2009 Mar

Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations
Org E, et al.
Hum Mol Genet 2009 Mar

 

 HuGE

Common variants at ten loci influence QT interval duration in the QTGEN Study
Newton-Cheh, C, et al.
Nat Genet 2009 Mar

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Page last reviewed: March 25, 2009 (archived document)
Page last updated: August 18, 2009
Content source: National Center for Chronic Disease Prevention and Health Promotion, Public Health Genomics