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| Thursday, January 22, 2009 |
Volume
22 Number 3 |
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| This weekly update provides information about the impact of human genomic research on disease prevention & population health. |
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Three New Recommendations for Genetic Tests Released by the EGAPP Working Group
This month the independent Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group, supported by the Centers for Disease Control and Prevention, released three new evidence-based recommendations on the validity and utility of specific genetic tests currently being used in clinical practice. Read more.
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New article, Influence of Family History of Diabetes on Health Care Provider Practice and Patient Behavior Among Nondiabetic Oregonians, published in the January 7, 2009 issue of Preventing Chronic Disease. Authors: Zlot AI, Bland MP, Silvey K, Epstein B, Mielke B, Leman RF. |
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New article, Developing Family Healthware, a Family History Screening Tool to Prevent Common Chronic Diseases, published in the January 7, 2009 issue of Preventing Chronic Disease. Authors: Yoon PW, Scheuner MT, Jorgensen C, Khoury MJ. |
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New article, Cardiovascular Disease Risk Prediction With and Without Knowledge of Genetic Variation at Chromosome 9p21.3, (136KB) published in the January 2, 2009 issue of Annals of Internal Medicine. Authors: Paynter NP, Chasman DI, Buring JE, Shiffman D, Cook NR, Ridker PM. Read an editorial Personalized Genetic Prediction: Too Limited, Too Expensive, or Too Soon? (70KB) by John PA Ioannidis. |
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New article, How to use an article about genetic association: C. What are the results and will they help me in caring for my patients?, published in the January 20, 2009 issue of the Journal of the American Medical Association. Authors: Attia J, Ioannidis J, Thakkinstian A, McEvoy M, Scott RJ, Minelli C, et al. |
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Presentations and other materials from the NIH and CDC Personal Genomics Workshop in December 2008 are now available online (172KB) |
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The American Public Health Association (APHA) Genomics Forum makes a call for genomics-related abstracts (576KB) for the 137th APHA Annual Meeting & Expo to be held November 7-11, 2009, in Philadelphia, Pennsylvania. Deadline: February 10, 2009. For more information, contact Dean Hosgood hosgoodd@mail.nih.gov. |

- The following are headlines from on-line news articles published during the past week.
- The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
- Free registration required for some articles.
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Genetic Testing |
EGAPP releases new genetic testing recommendations, Genetics & Public Policy Center, January 21 |
Genetic screenings increasing for cancer gene, KTUU.com, January 20 |
EGAPP recommendations on three genetic tests, PHG Foundation, January 20 |
EGAPP recommendations on three genetic tests, PHG Foundation, January 20 |
A genetic test for heart disease and cancer risk, Technology Review, January 22 |
Genetic testing not cost-effective in guiding initial dosing of blood-thinner warfarin, News-Medical.Net, January 20 |
deCODE launches cardio & cancer genetic scans, pharmabiz.com, January 21 |
Genetic testing hits new levels, The Times, January 16 |



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C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation
De Mattia E & Toffoli G
Eur J Cancer 2009 Jan
Genetics of bipolar disorder: successful start to a long journey
Craddock N & Sklar P
Trends Genet 2009 Jan
Proceedings of the international consensus conference on breast cancer risk, genetics, & risk management, April, 2007
Schwartz GF, et al.
Breast J 2009 Jan-2009 Feb;15(1):4-16
Connective Tissue and Related Disorders and Preterm Birth: Clues to Genes Contributing to Prematurity
Anum EA, et al.
Placenta 2009 Jan
Addiction Genetics and Pleiotropic Effects of Common Haplotypes that Make Polygenic Contributions to Vulnerability to Substance Dependence
Uhl GR, et al.
J Neurogenet 2009 Jan:1-11
Development and application of genotyping technologies
Shi J, et al.
Sci China C Life Sci 2009 Jan;52(1):17-23
Pharmacogenetics and pharmacogenomics of anticancer agents
Huang RS & Ratain MJ
CA Cancer J Clin 2009 Jan-2009 Feb;59(1):42-55
The Increasing Complexity of Mercaptopurine Pharmacogenomics
Marsh S & Van Booven D
Clin Pharmacol Ther 2009 Feb;85(2):139-41
Genetics of bone loss in rheumatoid arthritis--role of vitamin D receptor polymorphisms
Ranganathan P
Rheumatology (Oxford) 2009 Jan
Consistency of self-reported first-degree family history of cancer in a population-based study
Roth FL, et al.
Fam Cancer 2009 Jan
Screening for Hemophilia A Carriers: Utility of PCR-RFLP--Based Polymorphism Analysis
Tasleem Raza S, et al.
Clin Appl Thromb Hemost 2009 Feb;15(1):78-83
Cost-Effectiveness of Using Pharmacogenetic Information in Warfarin Dosing for Patients With Nonvalvular Atrial Fibrillation
Eckman MH, et al.
Ann Intern Med 2009 Jan;150(2):73-83
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
Meyre D, et al.
Nat Genet 2009 Jan
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study
Tanaka T, et al.
PLoS Genet 2009 Jan;5(1):e1000338
An updating meta-analysis of the GSTM1, GSTT1, and GSTP1 polymorphisms and prostate cancer: A HuGE Review
Mo Z, et al.
Prostate 2009 Jan
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