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Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
 
 
 Thursday, February 19, 2009 Volume 22   Number 7
banner update Family History Population Research Genomics in Practice General Public
This weekly update provides information about the impact of human genomic research on disease prevention & population health. open mailbox for email deliveryGet email updates
Spotlight
heart helix
February is American Heart Month
To raise awareness of heart disease, February was named American Heart Month. Family medical history offers important information for identifying individual risk of this disease. Learn more

Recommendations from the STrengthening the REporting of Genetic Association studies (STREGA) Initiative Released
Read more non-gov warning icon

Sections

blue dotView Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 Upcoming Events
Genomics Announcements
   
There are no announcements this week.


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

In the most lethal brain cancer newly discovered gene could be a prime target, non-gov warning icon Medical News Today, February 19

Genetically customized cancer treatments, non-gov warning icon CBS News, February 16

Gene linked to aggressive progression of liver cancer identified by researchers, non-gov warning icon Medical News Today, February 18

Questionnaire increased genetic counseling referrals for women... non-gov warning iconHemOncToday, February 13

Genetic identification of marker in lymph nodes appears associated with risk of colorectal cancer recurrence, non-gov warning icon Medical News Today, February 18

 


Cardiovascular Disease

Does gene show link between migraine and stroke or heart attacks, non-gov warning icon Medical News Today, February 17

Common gene variants increase risk of hypertension, may lead to new therapies, non-gov warning icon News-Medical.Net, February 16

Periodontitis and myocardial infarction: A shared genetic predisposition, non-gov warning icon Medical News Today, February 17

 

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Ethical, Legal and Social Issues (ELSI)

Pregnancy & gender test raises ethical questions, non-gov warning icon KSFY Action News, February 12

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Family History

Family history of melanoma doubles Parkinson Disease risk, non-gov warning icon U.S. News & World Report, February 16

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Genetic Testing

Gene testing application deadline nears, non-gov warning icon North County Times, February 15

Genetic test finds disease, not a cure, non-gov warning icon Charlotte Observer, February 15

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Mental Health

Alzheimer's disease may be passed on from parents due to faulty gene: researchers, non-gov warning icon Telegraph, February 18

Narrowing search for behavior-related genes in people with Williams syndrome, non-gov warning icon Medical New Today, February 13

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Newborn Screening

States expand newborn screening for life-threatening disorders, non-gov warning icon EurekAlert, February 18

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Other News

Adding genetics to a patient's clinical profile might lead to more accurate blood-thinner dosing, non-gov warning icon insciences.org, February 18

Picture emerging on genetic risks of IVF, non-gov warning icon New York Times, February 16

HMC lecture spotlights role of genetics in
medicines
, non-gov warning icon LDNews, February 18

Pharmacogenetic-based prescribing slow to take hold, non-gov warning icon Genome Web, February 16

For some counselors, it's in the genes, non-gov warning icon The Wall Street Journal, February 17

Genomics: The convoluted promise of our generation, non-gov warning icon The Crimson White, February 15

Guidelines for genetic-association studies
published
, non-gov warning icon GenomeWeb, February 17

Statistical analysis could yield new drug target for multiple sclerosis, News-Medical.Net, February 15

Star Trek-style device may check patients' genetic suitability to different medicines, non-gov warning icon newKerala.com, February 17

The secrets in Lincoln’s DNA, non-gov warning icon Newsweek, February 14

Gene Logic announces launch of Illumina SNP genotyping services, non-gov warning icon Gene Logic, February 16

Scientists unravel genetic codes and family trees of common cold viruses, non-gov warning icon Medical News Today, February 13

Insights into human genetic makeup provided by mixed population, non-gov warning icon Medical News Today, February 16

Next gen sequencing technology pinpoint 'on-off switches' in genomes, non-gov warning icon EurekAlert, February 12

Jumping genes play significant role in gene regulatory networks, non-gov warning icon News-Medical.Net, February 16

 
   
Genomics in Scientific Literature
Featured Item

Meta-analysis in genome-wide association studies
Zeggini E & Ioannidis JP
Pharmacogenomics 2009 Feb;10(2):191-201


 General Articles

Polymorphisms of pro-inflammatory genes and prostate cancer risk: a pharmacogenomic approach
Caruso C, et al.
Cancer Immunol Immunother 2009 Feb

Genotype-Phenotype Relationships of Presenilin-1 Mutations in Alzheimer's Disease: An Update
Larner AJ & Doran M
J Alzheimers Dis 2009 Feb

Experiences and Decisions that Motivate Women at Increased Risk of Breast Cancer to Participate in an Experimental Screening Program
Proulx M, et al.
J Genet Couns 2009 Feb

Strengthening the reporting of genetic association studies (STREGA)-an extension  of the strengthening the reporting of observational studies in epidemiology (STROBE) statement
Little J, et al.
J Clin Epidemiol 2009 Feb

Session 2: Personalised nutrition Genetic variation and disease risk: new advances
Scott J
Proc Nutr Soc 2009 Feb:1-9

Family-based genome-wide association studies
Benyamin B, et al.
Pharmacogenomics 2009 Feb;10(2):181-90

The future of genetics in psychology and psychiatry: microarrays, genome-wide association, and non-coding RNA
Plomin R & Davis OS
J Child Psychol Psychiatry 2009 Jan;50(1-2):63-71

GWA studies: rewriting the story of IBD
Budarf ML, et al.
Trends Genet 2009 Feb

NKX2.5 mutations and congenital heart disease: Is it a marker of cardiac anomalies?
Balci MM & Akdemir R
Int J Cardiol 2009 Feb

Likelihood ratio tests for maternal and fetal genetic effects on obstetric complications
Chen J, et al.
Genet Epidemiol 2009 Feb

Extracting a needle from a haystack: reanalysis of whole genome data reveals a readily translatable finding
Keers R, et al.
Psychol Med 2009 Feb:1-5

Distress among women receiving uninformative BRCA1/2 results: 12-month outcomes
O'Neill SC, et al.
Psychooncology 2009 Feb

Cancer Genetic Counselees' Self-Reported Psychological Distress, Changes in Life, and Adherence to Recommended Surveillance Programs 3-7 Years Post Counseling
Hayat Roshanai A, et al.
J Genet Couns 2009 Feb

Predictors of decision making in families at risk for inherited breast/ovarian cancer
Mellon S, et al.
Health Psychol 2009 Jan;28(1):38-47

Methods for analysis in pharmacogenomics: lessons from the Pharmacogenetics Research Network Analysis Group
Srinivasan BS, et al.
Pharmacogenomics 2009 Feb;10(2):243-51

Genome-wide association studies of coronary artery disease and heart failure: where are we going?
Dorn GW & Cresci S
Pharmacogenomics 2009 Feb;10(2):213-23

 

 Family History

Genetic assessment of breast cancer risk in primary care practice
Burke W, et al.
Am J Med Genet A 2009 Feb

Family history of suicide: A clinical marker for major depression in primary care practice?
Torzsa P, et al.
J Affect Disord 2009 Feb

Family letters are an effective way to inform relatives about inherited cardiac disease
van der Roest WP, et al.
Am J Med Genet A 2009 Feb

The relationship between knowledge of family history and cancer characteristics at diagnosis in women newly-diagnosed with invasive breast cancer
Lijovic M, et al.
Fam Cancer 2009 Feb

 

 Genetic Testing

Diagnosis of Hepatic Iron Overload: A Family Study Illustrating Pitfalls in Diagnosing Hemochromatosis
Schranz M, et al.
Diagn Mol Pathol 2009 Feb

Randomized trial of a decision aid for BRCA1/BRCA2 mutation carriers: impact on measures of decision making and satisfaction
Schwartz MD, et al.
Health Psychol 2009 Jan;28(1):11-9

Genetic association studies to detect adverse drug reactions: abacavir hypersensitivity as an example
Hughes AR, et al.
Pharmacogenomics 2009 Feb;10(2):225-33

Histopathological criteria and selection algorithms for BRCA1 genetic testing
Gadzicki D, et al.
Cancer Genet Cytogenet 2009 Mar;189(2):105-11

 

 Genome Wide

Genome-wide association study of acute post-surgical pain in humans
Kim H, et al.
Pharmacogenomics 2009 Feb;10(2):171-9

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1
Zheng W, et al.
Nat Genet 2009 Feb

 

 HuGE

Metaanalysis of Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms Affecting Methotrexate Toxicity
Fisher MC & Cronstein BN
J Rheumatol 2009 Feb

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The CDC Office of Public Health Genomics makes available the above information as a public service only. Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

 
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Page last reviewed: February 19, 2009 (archived document)
Page last updated: August 18, 2009
Content source: National Center for Chronic Disease Prevention and Health Promotion, Public Health Genomics