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Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
 
 
 Thursday, April 23, 2009 Volume 22   Number 16
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This weekly update provides information about the impact of human genomic research on disease prevention & population health. open mailbox for email deliveryGet email updates
Spotlight

Public Health GenomicsResearchers Are Encouraged to Submit Proposals for Projects on Comparative Effectiveness Research in Genomic and Personalized Medicine
Access the funding announcement. Read other public health genomics priorities.

Sections

blue dotView Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 Upcoming Events
Genomics Announcements
   
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New evidence report, Clinical Utility of Cancer Family History Collection in Primary Care, released by the Agency for Healthcare Research and Quality this month. View the report.PDF icon(1.6 MB)
   
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NIH's National Human Genome Research Institute solicits applications from academic institutions, community-based organizations, and other organizations for the 2009 Community Genetics Forum, a community engagement project that encourages and supports genetics education and public participation. Deadline for letter of intent: April 27, 2009. Deadline for proposals: May 25, 2009.

   
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The U.S. Equal Employment Opportunity Commission (EEOC) seeks public comment on proposed regulations implementing Genetic Information Non-Discrimination Act (GINA). Deadline: May 1, 2009. Read the press release.
 
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The Secretary's Advisory Committee on Genetics, Health, and Society (SACGHS) requests public comment on draft report on gene patents and licensing practices and their impact on patient access to genetic tests. Deadline: May 15, 2009. Read more.


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

Genetic testing in families battling breast cancer, non-gov warning icon ArklLaTex, April 22

National Cancer Institute’s Plan to accelerate cancer research announced, NIH News, April 20

Bowel cancer screening to be considered from age 25 for high risk group, non-gov warning icon News-Medical.Net, April 21

Researchers discover potential functional role of genetic variation in prostate cancer risk, NIH News, April 20

Mini Medical School session teaches about cancer, non-gov warning icon wthitv.com, April 21 

Experts highlight inroads to preventing cancer, non-gov warning icon Forbes, April 19

Dark hair? Don't burn? Your genes may still put you at risk for melanoma, non-gov warning icon EurekAlert, April 21

Genetic variations in MiRNA processing pathway and binding sites help predict ovarian cancer risk, non-gov warning icon Science Daily, April 19

Genetic analysis may predict risk of invasive bladder cancer, non-gov warning icon Medical News Today, April 21

Genetic source of rare childhood cancer found; gene is implicated in other cancers, non-gov warning icon PR Newswire, April 19

Researchers confirm gene variants associated with the most common adult leukemia, non-gov warning icon Medical News Today, April 21

Genetic testing helps survivor stay step ahead of disease, non-gov warning icon Elpasotimes.com, April 19

Lander talks cancer genomics at AACR meeting, non-gov warning icon GenomeWeb, April 21 [by free subscription only]

Personalized medicine helps cancer patients survive, non-gov warning icon EurekAlert, April 19

DPH launches new colorectal cancer & genetic testing resource, non-gov warning icon Connecticut Department of Public Health, April 20

TGen researchers discover possible way to block the spread of deadly brain tumors, non-gov warning icon EurekAlert, April 17

Expression Analysis announces cancer gene resequencing collaboration, non-gov warning icon Business Wire, April 20

Autopsy study links prostate cancer to single rogue cell, non-gov warning icon News-Medical.Net, April 16

Large study documents how P53 mutations link to high-grade breast cancer, poor outcomes, non-gov warning icon Medical News Today, April 20

 

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Cardiovascular Disease

Six new genes associated with heart attacks, non-gov warning icon PharmaLive.com, April 22 

Scientists find genes that could raise stroke risk by one-third, non-gov warning icon Daily Herald, April 20 

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Ethical, Legal and Social Issues (ELSI)

Ethics inquiry to judge challenges of genetic testing, non-gov warning icon Times Online, April 21

Examining ethics of lung cancer test, non-gov warning icon NPR, April 19

Genetic information law affects informed consent, non-gov warning icon FDA News, April 21

 

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Family History

Family history raises asthma risk, non-gov warning icon The Times of India, April 21

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Genetic Testing

Genetic testing reveals potential therapeutic target for CARASIL patients, non-gov warning icon Insidermedicine, April 22

'Commercial genetic psychiatric tests are irresponsible and harmful, say scientists', non-gov warning icon Medical News Today, April 17

Gene testing for melanoma risk reduces anxiety and depression, non-gov warning icon Medical News Today, April 21

Getting personal, non-gov warning icon The Economist, April 16

Study dismisses commercial DNA testing for disease, non-gov warning icon Turnto23.com, April 20

 

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Mental Health

Another gene found for Rett syndrome, non-gov warning icon News-Medical.Net, April 22

The Genetic X-Factor, non-gov warning icon Medical News Today, April 20

New light on bipolar treatment drugs, non-gov warning icon EurekAlert, April 21

Scientists find genes that could raise stroke risk by one-third, non-gov warning icon Daily Herald, April 20

Learning disabilities in males: Nine new X chromosome genes linked to learning disabilities, non-gov warning icon Science Daily, April 20

The pathways of Alzheimer's that strikes at the young: use of computational model, non-gov warning icon Medical News Today, April 17

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Other News

Mapping a human genome, via an eBay auction, non-gov warning icon The New York Times, April 22

Fish oil protects against neurodegenerative diseases, non-gov warning icon News-Medical.Net, April 20

USC researchers uncover clues about cause of Huntington's disease, non-gov warning icon Medical News Today, April 21

Free online toolkit provides standard measures for genome and population studies, NIH News, April 20

Genes that protect against aging identified by study, non-gov warning icon Medical News Today, April 21

Genetic findings offer hope for cures, non-gov warning icon The Edinburg Paper, April 20

Genetic study offers insight into immune system, non-gov warning icon Medical News Today, April 21

At risk for kidney disease? Check your genes, non-gov warning icon Science Daily, April 19

Genetics programs help people understand the risk for diseases, non-gov warning icon San Jose Mercury News, April 21

Fashion photographer finds beauty in genetic differences, non-gov warning icon Pennsylvania Local News, April 19

Genomic Medicine goes into ORBIT, non-gov warning icon Health Data Management, April 21

Genetic risk factors play role in autoantibody-negative rheumatoid arthritis, non-gov warning icon Science Daily, April 17

Learning how the pieces responsible for interpreting the human genome work, non-gov warning icon EurekAlert, April 21

Genetic switch potential key to new class of antibiotics, non-gov warning icon EurekAlert, April 17

Mini Medical School session teaches about cancer, non-gov warning icon wthitv.com, April 21

'Motorized' DNA opens door to autonomous molecular experiments, non-gov warning icon Medical News Today, April 17

New insights published in nature genetics on how cells change gears, non-gov warning icon Medical News Today, April 21

'Untangling the double helix,' new book explores enzymes responsible for maintaining genome integrity, non-gov warning icon Medical News Today, April 17

Signaling networks that set up genetic code, non-gov warning icon Science Daily, April 21

 

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Genomics in Scientific Literature
Featured Item

An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses
Janssens AC, et al.
Genet Med 2009 Mar;11(3):153-62


 General Articles

Michigan genetics plan: a report on the needs assessment process
Beene-Harris R & Bach JV
Health Promot Pract 2009 Apr;10(2):201-9

Genetic Risk Prediction -- Are We There Yet?
Kraft P & Hunter DJ
N Engl J Med 2009 Apr 360(16):1701-1703

Common Genetic Variation and Human Traits
Goldstein DB
N Engl J Med 2009 Apr;360(16):1696-98

Genomewide Association Studies -- Illuminating Biologic Pathways
Hirschhorn JN
N Engl J Med 2009 Apr;360(16):1699-1701

Genomewide Association Studies and Human Disease
Hardy J & Singleton A
N Engl J Med 2009 Apr;360(16):1759-68

Genetics of type 1A diabetes
Concannon P, et al.
N Engl J Med 2009 Apr;360(16):1646-54

Development of a fingerprinting panel using medically relevant polymorphisms
Cross DS, et al.
BMC Med Genomics 2009 Apr;2(1):17

HPV variants and HLA polymorphisms: the role of variability on the risk of cervical cancer
de Araujo Souza PS, et al.
Future Oncol 2009 Apr;5(3):359-70

CYP2D6 genotyping for psychiatric patients treated with risperidone: considerations for cost-effectiveness studies
Rodriguez-Antona C, et al.
Pharmacogenomics 2009 Apr;10(4):685-99

Variation in the COMT gene: implications for pain perception and pain treatment
Andersen S & Skorpen F
Pharmacogenomics 2009 Apr;10(4):669-84

Pharmacogenetics of nucleoside reverse-transcriptase inhibitor-associated peripheral neuropathy
Kallianpur AR & Hulgan T
Pharmacogenomics 2009 Apr;10(4):623-37

Pharmacogenetics and biomarkers in colorectal cancer
Strimpakos AS, et al.
Pharmacogenomics J 2009 Apr

Genotypic Approaches to Therapy in Children (GATC): Using Information Technology  to Improve Drug Safety
Wong E, et al.
Stud Health Technol Inform 2009;143:209-14


 Family History

Family history and risk for ischemic stroke: Sibling history is more strongly correlated with the disease than parental history
Choi JC, et al.
J Neurol Sci 2009 Apr

ApoE Genotype and Family History in Patients With Dementia and Cognitively Intact Spousal Controls
Zintl M, et al.
Am J Alzheimers Dis Other Demen 2009 Apr

Age at onset of bilateral breast cancer, the presence of hereditary BRCA1, BRCA2, CHEK2 gene mutations and positive family history of cancer
Skasko E, et al.
Onkologie 2009 Apr;32(4):182-8


 Genetic Testing

Parental perspective of the benefits of genetic testing in children with congenital deafness
Geelhoed EA, et al.
Public Health Genomics 2009;12(4):245-50

Advances in genetic testing for Alzheimer's disease
Howard KL & Filley CM
Rev Neurol Dis 2009 Winter;6(1):26-32


 Genome Wide

Genomewide Association Studies of Stroke
Ikram MA, et al.
N Engl J Med 2009 Apr

A genome screen of successful aging without cognitive decline identifies LRP1B by haplotype analysis
Poduslo SE, et al.
Am J Med Genet B Neuropsychiatr Genet 2009 Apr


 HuGE

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The CDC Office of Public Health Genomics makes available the above information as a public service only. Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

 
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Page last updated: April 23, 2009 (archived document)
Content source: National Center for Chronic Disease Prevention and Health Promotion, Public Health Genomics