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Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
 
 
 Thursday, April 16, 2009 Volume 22   Number 15
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This weekly update provides information about the impact of human genomic research on disease prevention & population health. open mailbox for email deliveryGet email updates
Spotlight

Public Health GenomicsResearchers Are Encouraged to Submit Proposals for Projects on Comparative Effectiveness Research in Genomic and Personalized Medicine
Access the funding announcement. Read other public health genomics priorities.

Sections

blue dotView Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 Upcoming Events
Genomics Announcements
   
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NIH's National Human Genome Research Institute solicits applications from academic institutions, community-based organizations, and other organizations for the 2009 Community Genetics Forum, a community engagement project that encourages and supports genetics education and public participation. Deadline for letter of intent: April 27, 2009. Deadline for proposals: May 25, 2009.

 
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New article, The need for genetic variant naming standards in published abstracts of human genetic association studies, non-gov warning icon published in the April 14, 2009 issue of BMC Research Notes on a new component of the HuGE Navigator, non-gov warning icon  the Variant Name Mapper. non-gov warning icon Authors: Yu W, Ned R, Wulf A, Liu T, Khoury MJ and Gwinn M.
   
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The U.S. Equal Employment Opportunity Commission (EEOC) seeks public comment on proposed regulations implementing Genetic Information Non-Discrimination Act (GINA). Deadline: May 1, 2009. Read the press release.
 
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The Secretary's Advisory Committee on Genetics, Health, and Society (SACGHS) requests public comment on draft report on gene patents and licensing practices and their impact on patient access to genetic tests. Deadline: May 15, 2009. Read more.


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

Discovery of potential genetic predisposition for lung cancer, non-gov warning icon News-Medical.Net, April 16 

For cancer cells, genetics alone is poor indicator for drug response, non-gov warning icon News-Medical.Net, April 12

Science Magazine to host webinar on advances in cancer genomics, non-gov warning icon PR Web, April 15 

Gene fusion discovery may lead to improved prostate cancer test, non-gov warning icon Medical News Today, April 10

Discovery of chemical compound that may stop deadly brain tumors, non-gov warning icon News-Medical.Net, April 12

Identification of biomarker associated with poor outcome in aggressive childhood cancer, non-gov warning icon Medical News Today, April 10

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Cardiovascular Disease

Ethical, Legal and Social Issues

Discovery of gene variation linked to increased risk of ischemic stroke, non-gov warning icon News-Medical.Net, April 16

NIH Stimulus grants to consider bioethics, non-gov warning icon Genome Web, April 13 [by free subscription only]

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Epigenetics

Family History

You are what your mother did not eat during pregnancy, non-gov warning icon News-Medical.Net, April 14

Living with a 'faulty gene', non-gov warning icon BBC News, April 9

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Genetic Testing

More work needed to standardize consumer genomics offerings, top US health official says, non-gov warning icon Genome Web, April 14 [by free subscription only]

$99,000 to see your future, non-gov warning icon MSN, April 10

Doctor, I've got a problem with my genome..., non-gov warning icon Times Online, April 14

Need a health MOT? Send for Mrs Google's testing kit, non-gov warning icon Mail Online, April 10

New genetics tests locally, non-gov warning icon knoxnews.com, April 13

Do-it-yourself DNA testing: Helpful or harmful, non-gov warning icon MSNBC, April 9

Genomic Medicine Institute: Bringing genomics to community patients, non-gov warning icon Blisstree, April 12

 

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Mental Health

Australian study will explore genetic causes of ADHD, non-gov warning icon Medical News Today, April 13

Gene variant tied to schizophrenia, non-gov warning icon Forbes, April 9

Discovery of novel mechanisms that might causally link type-2 diabetes to Alzheimer's disease, non-gov warning icon News-Medical.Net, April 13

 

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Other News

Novel procedure for sequencing the human genome, non-gov warning icon Science Daily, April 16

CSHL researchers explain process by which cells 'hide' potentially dangerous DNA segments, non-gov warning icon Medical News Today, April 13

Cedars-Sinai seeks patients with Keratoconus for study examining genetic basis for the disease, non-gov warning icon Medical News Today, April 15

New book series presented by Wiley-Blackwell and the American Heart Association, non-gov warning icon Medical News Today, April 13

The DECIPHER database - revolutionising clinical practice and genetic research, non-gov warning icon Medical News Today, April 15

UCB  collaborates in the MetaHIT project to decipher the human metagenome, non-gov warning icon Medical News Today, April 13

Genes show limited value in predicting diseases, non-gov warning icon The New York Times, April 15

ADHD study to investigate genetic link, non-gov warning icon The Herald Sun, April 12

Genetic differences influence risk of developing proteinuria, non-gov warning icon Medical News Today, April 15

RNA interference can be used to silence genes selectively - potential for Huntington's disease therapy, non-gov warning icon News-Medical.Net, April 12

HTG announces availability of new 384/9 gene expression assay, non-gov warning icon Medical News Today, April 15

Twins provide clues to genetic risk factors in autoantibody-negative rheumatoid arthritis, non-gov warning icon News-Medical.Net, April 11

Survey: Vets supportive of genetic cohort study, non-gov warning icon Genome Web, April 14 [by free subscription only]

University Of Michigan installs second Genomatix Genome Analyzer, non-gov warning icon Medical News Today, April 11

Freeport family suffers from genetic ailment, non-gov warning icon thefacts.com, April 14

Natural born leaders, non-gov warning icon Medical News Today, April 10

Study finds genetic variants that increase osteoporosis risk in Asian women, non-gov warning icon Clinica, April 14

NIH outlines stimulus challenge grants for genomics, non-gov warning icon GenomeWeb, April 10 [by free subscription only]

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Pharmacogenomics

Designer drugs, non-gov warning icon IBJ.com, April 11

Should you customize your drugs to your DNA, non-gov warning icon MSNBC, April 9

   
Genomics in Scientific Literature
Featured Item

A novel haplotype-sharing approach for genome-wide case-control association studies implicates the calpastatin gene in Parkinson's disease
Allen AS & Satten GA
Genet Epidemiol 2009 Apr


 General Articles

Risk Perception Among Women at Risk for Hereditary Breast and Ovarian Cancer
Pilarski R
J Genet Couns 2009 Apr

The Genetics of Bipolar Disorder
Barnett JH & Smoller JW
Neuroscience 2009 Apr

Recent progress in rheumatoid arthritis genetics: one step towards improved patient care
Plenge RM
Curr Opin Rheumatol 2009 Apr

Creating a genetic risk score for coronary artery disease
Dandona S & Roberts R
Curr Atheroscler Rep 2009 May;11(3):175-81

Gene-environment interaction tests for dichotomous traits in trios and sibships
Hoffmann TJ, et al.
Genet Epidemiol 2009 Apr

Viability of in-house datamarting approaches for population genetics analysis of  SNP genotypes
Amigo J, et al.
BMC Bioinformatics 2009;10 Suppl 3:S5

Genetics of stroke
Fornage M
Curr Atheroscler Rep 2009 May;11(3):167-74

The Inherited Genetic Component of Sporadic Pancreatic Adenocarcinoma
Milne RL, et al.
Pancreatology 2009 Apr;9(3):206-14

Susceptibility genes & modifiers for cardiac arrhythmias
Schulze-Bahr E
Prog Biophys Mol Biol 2008 Oct-2008 Nov;98(2-3):289-300

On testing for genetic association in case-control studies when population allele frequencies are known
Antonyuk A & Holmes C
Genet Epidemiol 2009 Apr

 

 Family History

Lung Cancer Genetics: A Family Affair?
Christiani DC
Clin Cancer Res 2009 Apr

Family history of suicide and personality
Sarchiapone M, et al.
Arch Suicide Res 2009;13(2):178-84

Familial risks in nervous-system tumours: a histology-specific analysis from Sweden and Norway
Hemminki K, et al.
Lancet Oncol 2009 Apr


 Genetic Testing

Genetic testing for hereditary nonpolyposis colorectal cancer (HNPCC)
Hegde MR & Roa BB
Curr Protoc Hum Genet 2009 Apr;Chapter 10:Unit 10.12

Successful translation of pharmacogenetics into the clinic: the abacavir example
Phillips E & Mallal S
Mol Diagn Ther 2009;13(1):1-9

Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out
Neumann HP, et al.
Cancer Res 2009 Apr

Clinical utility of the ABCR400 microarray: basing a genetic service on a commercial gene chip
Roberts LJ, et al.
Arch Ophthalmol 2009 Apr;127(4):549-54

Development of Genomic Reference Materials for Cystic Fibrosis Genetic Testing
Pratt VM, et al.
J Mol Diagn 2009 Apr

A Decade of Genetic Counseling in Frontotemporal Dementia Affected Families: Few  Counseling Requests and much Familial Opposition to Testing
Riedijk SR, et al.
J Genet Couns 2009 Apr

 

 Genome Wide

Acyl-CoA synthetase long-chain family member 6 is associated with premature ovarian failure
Kang H, et al.
Fertil Steril 2009 Apr;91(4 Suppl):1339-43

A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length
Mangino M, et al.
J Med Genet 2009 Apr

Identification of Genetic Markers Associated With High-Density Lipoprotein-Cholesterol by Genome-Wide Screening in a Japanese Population
Hiura Y, et al.
Circ J 2009 Apr

 

 HuGE

Please visit the HuGE Navigator.

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The CDC Office of Public Health Genomics makes available the above information as a public service only. Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

 
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 Provides link to non-governmental sites and does not necessarily represent the views of the Centers  for Disease Control and Prevention.

Page last updated: April 16, 2009 (archived document)
Content source: National Center for Chronic Disease Prevention and Health Promotion, Public Health Genomics