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Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
 
 
 Thursday, February 7, 2008 Volume 20   Number 6
Update banner Family History Population Research Genomics in Practice General Public
This weekly update provides information about the impact of human genomic research on disease prevention & population health. open mailbox for email deliveryGet email updates
Spotlight
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Letting the Genome Out of the Bottle — Will We Get Our Wish?
New genomic technologies are becoming readily available to the general public; however, little objective information exists to guide clinical or public health decision-making about their effectiveness or appropriate use.

February is American Heart Month
Heart disease is the leading cause of death in the United States and a major cause of disability. To raise awareness of this disease, since 1963, Congress has requested that the President proclaim February as “American Heart Month.”
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Sections

blue dotView Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 Upcoming Events

Genes, Environment, & Health Initiative: Translating Whole Genome Association Data into Clinical Practice

Personalized Medicine Coalition’s Fourth Annual Keynote Luncheon Address on the State of Personalized Medicine non-gov warning icon

Religion and Genomics: Navigating Pathways and Perspectives of Patient Care  non-gov warning icon

 Let's Go Surfing

Call for Papers: Genomic Medicine

Ghost in Your Genes non-gov warning icon

2008 At-A-Glance: Translating Gene Discoveries into Population Health Benefits

Genomics Announcements
 
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New journal, Public Health Genomics, non-gov warning icon (a continuation of Community Genetics), expands the scope from medical genetics to include all topics related to the translation of genome-based science into population health improvements.

   
CDC sponsored material
 CDC's National Office of Public Health Genomics seeks a new geneticist. For more information about this position, click on the U.S. Department of Health and Human Services website and enter the vacancy number (HHS-CDC-T2-2008-0158 – for current employees or HHS-CDC-D2-2008-0091 – for non-federal applicants). The deadline to apply is February 15, 2008.
   
CDC sponsored material
 CDC's National Office of Public Health Genomics announces a new funding opportunity for those interested in genomics translation research.
Final applications are due: February 27, 2008. If you have questions, send us an email at genetics@cdc.gov.
   
CDC sponsored material
 The CDC/Emory University Public Health Genomics Institute: A Scientific Foundation for Closing the Gap Between Human Genome Discoveries and Population Health, originally planned for June 10-12, 2008, is postponed. More information about the future Institute is forthcoming. To receive updates, send us an email at cdcinfo@cdc.gov


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

Evidence found of gene that plays a suppressor role in skin cancer development, non-gov warning icon Medical News Today, February 7

 Researchers find biological factors that may drive prostate tumor aggressiveness in African-American men, non-gov warning icon NIH News, February 1

3 breast cancer gene tests 'promising', non-gov warning icon WebMD, February 4

 

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Cardiovascular Disease

  

Gene linked to increased risk of developing inflammatory arthritis may also increase patients' risk of dying from cardiovascular disease, non-gov warning icon Medical News Today, February 1

Ottawa team identifies genes that increase heart disease risk, non-gov warning icon Canada, Medical News Today, February 1

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Ethical, Legal and Social Issues (ELSI)

Concerns over online genetic tests, non-gov warning icon Red Orbit, February 4

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Family History  

You are not always victim of your genes, non-gov warning icon Central Florida News, February 4

Women need family heart history, non-gov warning icon 9WSYR.com, January 31

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Genetic Testing

Australian gene test opens door to personalised care, non-gov warning icon News-Medical.Net, February 6

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Mental Health

Paper outlines approach to genetic diagnosis in autism, non-gov warning icon Newswise, February 6

Major genetics breakthrough achieved by scientists, non-gov warning icon Medical News Today, February 1

Gene variants protect against adult depression triggered by childhood stress, non-gov warning icon NIH News, February 4

New gene linked to Fragile X syndrome -- suggests potential targets for autism and other neurological disorders, non-gov warning icon Science Daily,
February 1

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Other News

'Billy Bunter' genes children more likely to be overweight, non-gov warning icon Evening News, February 7

 Variation in the BCL11A gene linked to moderated symptoms of beta-thalassemia, non-gov warning icon News-Medical.Net, February 4

Obesity 'may be largely genetic', non-gov warning icon BBC News, February 7

Genesis of adult leukemia being mapped, non-gov warning icon Medical News Today, February 2

Disrupted genetic regulation causes common disturbance in metabolism of fat, non-gov warning icon News-Medical.Net, February 5

Argos therapeutics publishes novel approach to amplifying HIV genes for personalized immunotherapy treatments for HIV, non-gov warning icon Medical News Today, February 1

Genetic mutations in the Toll-like receptor 4 gene increase risk of preterm birth, non-gov warning icon News-Medical.Net, February 5

Genetic mutations may contribute to preterm birth risk - previously undiscovered mutations linked to blood clots and inflammation, non-gov warning icon Medical News Today, February 1

Researchers identify a worldwide-distributed clone of bacteria responsible for Legionnaire's disease, non-gov warning icon EurekAlert, February 5

Research confirms genetic skin barrier defect linked to eczema, non-gov warning icon Medical News Today, February 1

Cold sores have genetic link, study says, non-gov warning icon The Daily Utah Chronicle, February 4

Exposure to secondhand smoke linked to worsening of lung function in cystic fibrosis sufferers, non-gov warning icon News-Medical.Net, January 31

Gene linked to preterm birth among Hispanic women, non-gov warning icon Medical News Today, February 4

Inherited individual variations influence patterns of gene shuffling, non-gov warning icon EurekAlert, January 31

Medical world watching as Kansas baby battles disease, non-gov warning icon LJWorld.com, February 4

  
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Genomics in Scientific Literature
Featured Item

Interactions between secondhand smoke and genes that affect cystic fibrosis lung  disease
Collaco JM, et al.
JAMA 2008 Jan;299(4):417-24
 General Articles

Multiplex RT-PCR Amplification of HIV Genes to Create a Completely Autologous DC-Based Immunotherapy for the Treatment of HIV Infection.
Tcherepanova I, et al.
PLoS ONE. 2008 Jan 30;3(1):e1489.

The genetics of anorexia nervosa collaborative study: Methods and sample description
Kaye WH, et al.
Int J Eat Disord 2008 Jan

Interaction between genes and lifestyle factors on obesity
Marti A, et al.
Proc Nutr Soc 2008 Feb;67(1):1-8

Toll-like receptor polymorphisms and susceptibility to human disease
Misch EA & Hawn TR
Clin Sci (Lond) 2008 Mar;114(5):347-60

beta(1)-adrenoceptor polymorphisms: deviation of clinical outcome with use of beta-blockers in ventricular dysfunction
Tabrizchi R
Expert Rev Cardiovasc Ther 2008 Feb;6(2):145-7

Genomic approaches to bone and joint diseases. A genome-wide approach for analysis of polygenic diseases
Sato H & Emi M
Clin Calcium 2008 Feb;18(2):176-81

How will information about the genetic risk of mental disorders impact on stigma?
Spriggs M, et al.
Aust N Z J Psychiatry 2008 Mar;42(3):214-20

Influence of DNA damage and repair upon the risk of treatment related leukemia
Guillem V & Tormo M
Leuk Lymphoma 2008 Feb;49(2):204-17

 

 Genetic Testing

Interpersonal responses among sibling dyads tested for BRCA1/BRCA2 gene mutations
Hamann HA, et al.
Health Psychol 2008 Jan;27(1):100-9

 Family History

Desmoid tumors in a dutch cohort of patients with familial adenomatous polyposis
Nieuwenhuis MH, et al.
Clin Gastroenterol Hepatol 2008 Feb;6(2):215-9

Elevated liver enzymes in women with a family history of diabetes
Inoue K, et al.
Diabetes Res Clin Pract 2008 Jan

Family history of insomnia in a population-based sample
Beaulieu-Bonneau S, et al.
Sleep 2007 Dec;30(12):1739-45

Familial risk of oral clefts by morphological type and severity: population based cohort study of first degree relatives
Sivertsen A, et al.
BMJ 2008 Feb

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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For more information on HuGE, please visit the HuGENet™ home page

 

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The CDC National Office of Public Health Genomics makes available the above information as a public service only. Providing
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Page last updated: February 7, 2008 (archived document)
Content source: National Center for Chronic Disease Prevention and Health Promotion, Public Health Genomics