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• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Cancer
Genetic information improves prognosis and relapse-free survival prediction for breast cancer patients,   Medical News Today, April 2	Racial differences in response to bowel cancer genetic risk factor,  Medical News Today, March 31
NIDA researchers identify genetic variant linked to nicotine addiction and lung cancer, NIH News, April 2

FTO: the first gene contributing to common forms of human obesity
Loos RJ & Bouchard C
Obes Rev 2008 Mar

Educational needs in genetic medicine: primary care perspectives
Trinidad SB, et al.
Community Genet 2008;11(3):160-5

Participant characteristics that influence consent for genetic research in a population-based survey: the Baltimore epidemiologic catchment area follow-up
Mezuk B, et al.
Community Genet 2008;11(3):171-8

Cytochrome p450 enzyme polymorphism frequency in indigenous and native american populations: a systematic review
Jaja C, et al.
Community Genet 2008;11(3):141-9

Bioinformatics and genomics for opening new perspective for personalized care
Tanaka H
Stud Health Technol Inform 2008;134:47-58

Role of Pharmacogenetics of Immunosuppressive Drugs in Organ Transplantation
Thervet E, et al.
Ther Drug Monit 2008 Apr;30(2):143-50

The FH mutation database: an online database of fumarate hydratase mutations involved in the MCUL (HLRCC) tumor syndrome and congenital fumarase deficiency
Bayley JP, et al.
BMC Med Genet 2008 Mar;9(1):20

SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis
Constantine CC, et al.
BMC Med Genet 2008 Mar;9(1):18

Classification of genetic profiles of Crohn's disease: a focus on the ATG16L1 gene
Grant SF, et al.
Expert Rev Mol Diagn 2008 Mar;8(2):199-207

Pharmacogenomics in Alzheimer's disease
Cacabelos R
Methods Mol Biol 2008;448:213-357

Pharmacogenomics of drug-metabolizing enzymes and drug transporters in chemotherapy
Bosch TM
Methods Mol Biol 2008;448:63-76

Alzheimer's disease: epidemiology, genetics, and beyond
Wang XP & Ding HL
Neurosci Bull 2008 Mar;24(2):105-9

Irinotecan Pharmacogenetics in Japanese Cancer Patients: Roles of UGT1A1(*)6 and  (*)28
Sai K, et al.
Yakugaku Zasshi 2008 Apr;128(4):575-84

 

Telephone Genetic Counseling for High-Risk Women Undergoing BRCA1 and BRCA2 Testing: Rationale and Development of a Randomized Controlled Trial
Peshkin BN, et al.
Genet Test 2008 Spring;12(1):37-52

Professional challenges in cancer genetic testing: who is the patient?
Chan-Smutko G, et al.
Oncologist 2008 Mar;13(3):232-8

Telephone Genetic Counseling for High-Risk Women Undergoing BRCA1 and BRCA2 Testing: Rationale and Development of a Randomized Controlled Trial
Peshkin BN, et al.
Genet Test 2008 Mar

CFTR Mutations in Turkish and North African Cystic Fibrosis Patients in Europe: Implications for Screening
Lakeman P, et al.
Genet Test 2008 Spring;12(1):25-35

Predictive genetic testing of children for adult-onset diseases and psychological harm
Malpas PJ
J Med Ethics 2008 Jul;34(4):275-8

Factors Determining Dissemination of Results and Uptake of Genetic Testing in Families with Known BRCA1/2 Mutations
Finlay E, et al.
Genet Test 2008 Spring;12(1):81-91

Evaluating Online Direct-to-Consumer Marketing of Genetic Tests: Informed Choices or Buyers Beware?
Geransar R & Einsiedel E
Genet Test 2008 Spring;12(1):13-23

The clinical management of BRCA1 and BRCA2 mutation carriers
Gulati AP & Domchek SM
Curr Oncol Rep 2008 Jan;10(1):47-53

Multiple endocrine neoplasia syndromes, children, Hirschsprung's disease and RET
Moore SW & Zaahl MG
Pediatr Surg Int 2008 Mar

 

Gail Model Risk Factors: Impact of Adding an Extended Family History for Breast Cancer
Crispo A, et al.
Breast J 2008 Mar

Development and preliminary validation of the cancer family impact scale for colorectal cancer
Sinicrope PS, et al.
Genet Test 2008 Spring;12(1):161-9

How should we construct psychiatric family history scores? A comparison of alternative approaches from the Dunedin Family Health History Study
Milne BJ, et al.
Psychol Med 2008 Mar:1-10

Familial risks for cancer as the basis for evidence-based clinical referral and counseling
Hemminki K, et al.
Oncologist 2008 Mar;13(3):239-47

 

Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene
Capon F, et al.
Hum Mol Genet 2008 Mar

The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome
Firmann M, et al.
BMC Cardiovasc Disord 2008 Mar;8(1):6

Genome-wide association scan identifies a colorectal cancer susceptibility locus  on 11q23 and replicates risk loci at 8q24 and 18q21
Tenesa A, et al.
Nat Genet 2008 Mar

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease Loci
Liu Y, et al.
PLoS Genet 2008 Mar;4(3):e1000041

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For more information on HuGE, please visit the HuGENet™ home page