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three generations of women, big data word cloud, Health Literacy  and DNA in a pill capsule

Volume 33  Number 15  October 16-22, 2014About the Update

 

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Reports and Publications


Birth Defects & Child Health

mom looking at her baby

An approach to pediatric exome and genome sequencing
Biesecker LG & Biesecker BB Curr Opin Pediatr 2014 Oct

Obstetrician-gynecologists' knowledge of sickle cell disease screening and management
Azonobi IC, et al. BMC Pregnancy Childbirth 2014 Oct;14(1):356

Chronic Diseases

Ethics, Policy & Law

stacked books with a gavel infront of them

Changes on the horizon for consumer genomics in the EU
Louiza Kalokairinou et al. Science, October 17, 2014

Clinical integration of next generation sequencing: a policy analysis
Kaufman D, et al. J Law Med Ethics 2014 Sep;42 Suppl 1:5-8

NIH issues genomic data sharing policy
Nat Biotechnol 2014 Oct;32(10):966

Personal genomics and gene editing revolutions beg for global regulatory rethink, by Meredith Knight, Genetic Literacy Project, Oct 14

Infectious Diseases

an infected cell

Oral, capsulized, frozen fecal microbiota transplantation for relapsing clostridium difficile infection
Ilan Youngster, et al. JAMA, October 11, 2014

Ebola virus disease in the Democratic Republic of Congo
Gaël D. Maganga, et al. NEJM, October 15, 2014

UCSC Ebola genome browser now online to aid researchers' response to crisis, by Guy Lasnier, UCSC News, Oct 1

House fly genome deciphered in hunt for pest, pathogen control clues, GenomeWeb, Oct 14 [by free subscription only]

Research looks for genetic link to Valley Fever, by Alexandra Olgin, KJZZ, Oct 13

OMIC tools: A workflow for omic data analysis (NGS, microarray, PCR, MS, NMR)

OMICtools: an informative directory for multi-omic data analysis
Henry VJ, et al. Database, Jul 2014.

Culture-independent diagnostic testing: have we opened Pandora's box for good?
Janda JM, Abbott SA. Diag Microbiol Infect Dis 2014; 80(3): 171–176.

Leading the way: driving the delivery of pathogen genomics into practice, by Moorthie S, Luheshi L., PHG Foundation, Sep 2014

Bioinformatics tools extracted from a typical mammalian genome project, by Mangan M., OpenHelix blog post, Oct 6

New developments of RNAi in Paracoccidioides brasiliensis: prospects for high-throughput, genome-wide, functional genomics
Goes T, et al. PLoS Negl Trop Dis 2014; 8(10): e3173.

Resolution threshold of current molecular epidemiology of diphtheria
Mokrousov I. Emerg Infect Dis, Nov 2014.

Evaluation of broad-range 16S rRNA PCR for the diagnosis of bloodstream infections: two years of experience
Hassan RM, et al. J Infect Dev Ctries 2014;8(10):1252-1258.

Recombination drives genome evolution in outbreak-related Legionella pneumophila isolates
Sanchez-Buso L, et al. Nat Genet, Oct 5, 2014.

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
Gire SK, et al. Science 2014; 345: 1369-1372.

Portrait of a killer: genome of the 2014 EBOV outbreak strain
Basler CF. Cell Host Microbe 2014; 16(4): 419–421.

Insights into the early epidemic spread of Ebola in Sierra Leone provided by viral sequence data
Stadler T, et al. PLoS Curr (Outbreaks), Oct 6, 2014.

Molecular characterization of enteroviruses including a new type EV-C99 isolated from Xinjiang students in Shandong, China in 2011
Tao Z, et al. Sci Rep, Oct 9, 2014.

Nodding syndrome—a new hypothesis and new direction for research
Colebunders R, et al. Int J Infect Dis 2014; 27: 74–77.

Genomic definition of hypervirulent and multidrug-resistant Klebsiella pneumoniae clonal groups
Bialek-Davenet S, et al. Emerg Infect Dis, Nov 2014.

A delicate balance: maintaining mutualism to prevent disease
Van Tyne D, et al. Cell Host Microbe 2014; 16(4): 425–427.

Re-appraisal of old and new diagnostic tools in the current management of chronic hepatitis B, by Bessone F., Medscape [by free subscription only]

Reappraisal of known malaria resistance loci in a large multicenter study
Malaria Genomic Epidemiology Network. Nat Genet, Sep 28, 2014.

Malaria severity influenced by five human genes, say researchers, by Paddock C., Medical News Today, Sep 29

Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages
Marr AK, et al. PLoS Pathog 10(10): e1004419.

A modified γ-retrovirus vector for X-linked severe combined immunodeficiency
Hacein-Bey-Abina S, et al. N Engl J Med 2014; 371:1407-1417.

Genomic pathogen surveillance in animals: An early warning system for future pandemics? By Dr Chris Rands, PHG Foundation, Oct 7

Newborn Screening

Reviews, News & Commentaries

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CDC-Authored Genomics Publications

hand holding a pen on an article

CDC authors are indicated in bold

The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG).
Chen RT, Carbery B, Mac L, Berns KI, Chapman L, Condit RC, Excler JL, Gurwith M, Hendry M, Khan AS, Khuri-Bulos N, Klug B, Robertson JS, Seligman S, Sheets R, Williamson AL; for the V3SWG. Vaccine. 2014 Oct 8. pii: S0264-410X(14)01303-6.

Oseltamivir-Resistant Influenza A(H1N1)pdm09 Viruses, United States, 2013–14
Margaret Okomo-Adhiambo, Alicia M. Fry, Su Su, Ha T. Nguyen, Anwar Abd Elal, Elizabeth Negron, Julie Hand, Rebecca J. Garten, John Barnes, Xu Xiyan, Julie M. Villanueva, Larisa V. GubarevaComments to Author , and 2013–14 US Influenza Antiviral Working Group Emerg Infect Dis Jan, 2015.

Comparative genomic analysis of genogroup 1 (Wa-like) rotaviruses circulating in the USA, 2006-2009.
Roy S, Esona MD, Kirkness EF, Akopov A, Kyle McAllen J, Wikswo M, Cortese MM, Payne DC, Parashar U, Gentsch JR, Bowen MD; National Rotavirus Strain Surveillance System; New Vaccine Surveillance System. Infect Genet Evol. 2014 Oct 6. pii: S1567-1348(14)00353-0.

View previous CDC-authored publications

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About the Genomics & Health Impact Update

The Update includes genomics and health impact news and publications, CDC announcements, reports, blogs, podcasts, and other products. The Update features genomic tests, family history, programs and practice, policy and legislation and public health science.  Features of the week are archived under the Genomics & Health Resources A to Z page. To receive the update electronically every week sign-up here.

 

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The CDC Office of Public Health Genomics makes available the above information as a public service only. The items in the update come from news articles and scientific articles and abstracts published during the past week. The headlines and lead sentences are exactly as they appear & do not necessarily reflect the opinions, recommendations, or endorsement by the CDC.  Note that some links may become invalid over time.

 



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