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U.S. Genome Variation Estimates

NQO1 Allele and Genotype Frequencies

Available polymorphism(s)

rs number

Common Designations

Nucleotide change Amino acid

Genotyping method

rs10517

Ex6-457C>T

TaqMan

rs1800566

Ex6+40C>T
609C>T

Pro187Ser
Pro149Ser
Pro153Ser

TaqMan

rs34755915

IVS3+20G>A

TaqMan

rs689452

IVS1-27C>G

TaqMan

rs689453

Ex2+65G>A

Glu24Glu

TaqMan



Allele and Genotype Frequencies for Subpopulations


By Race/Ethnicity

VariantRace-ethnicityAllele
% (95% CI)
Chi-square
P-value†
Genotype
% (95% CI)
Chi-square
P-value†
HW
P-value‡
rs10517CTCCCTTT
Non-Hispanic White86.8 (85.7, 87.9)13.2 (12.1, 14.3)<0.00175.5 (73.5, 77.3)22.8 (21.0, 24.7)1.8 (1.2, 2.6)0.0010.65
Non-Hispanic Black86.1 (84.6, 87.5)13.9 (12.5, 15.4)73.9 (71.4, 76.3)24.3 (22.2, 26.6)1.7 (1.1, 2.7)0.65
Mexican American93.5 (91.7, 94.9)6.5 (5.1, 8.3)87.2 (83.8, 90.0)12.6 (9.8, 16.0)0.2 (0.1, 0.5)0.20
Total*86.4 (85.1, 87.7)13.6 (12.3, 14.9)75.0 (73.0, 77.0)22.9 (21.4, 24.4)2.1 (1.5, 3.0)
rs1800566CTCCCTTT
Non-Hispanic White80.6 (78.7, 82.4)19.4 (17.6, 21.3)<0.00164.7 (61.2, 68.0)31.8 (28.7, 35.1)3.5 (2.8, 4.3)<0.0010.51
Non-Hispanic Black81.2 (80.0, 82.3)18.8 (17.7, 20.0)65.8 (64.1, 67.5)30.7 (29.1, 32.3)3.5 (2.7, 4.6)0.93
Mexican American63.2 (61.2, 65.1)36.8 (34.9, 38.8)40.4 (37.5, 43.4)45.6 (42.8, 48.4)14.0 (12.4, 15.8)0.93
Total*78.5 (76.8, 80.2)21.5 (19.8, 23.2)61.8 (58.8, 64.7)33.4 (30.8, 36.2)4.8 (4.1, 5.6)
rs34755915AGAAAGGG
Non-Hispanic White1.8 (1.5, 2.3)98.2 (97.7, 98.5)<0.0010.0 (0.0, 0.4)3.5 (2.9, 4.4)96.4 (95.6, 97.1)<0.0010.81
Non-Hispanic Black0.4 (0.2, 0.8)99.6 (99.2, 99.8)0.0 (NA)0.8 (0.4, 1.6)99.2 (98.4, 99.6)0.88
Mexican American0.5 (0.3, 0.9)99.5 (99.1, 99.7)0.0 (NA)1.1 (0.6, 1.8)98.9 (98.2, 99.4)0.82
Total*1.4 (1.1, 1.8)98.6 (98.2, 98.9)0.0 (0.0, 0.3)2.8 (2.2, 3.5)97.2 (96.5, 97.8)
rs689452CGCCCGGG
Non-Hispanic White88.1 (87.1, 89.0)11.9 (11.0, 12.9)<0.00177.5 (75.7, 79.3)21.1 (19.4, 23.0)1.3 (0.9, 2.0)<0.0010.23
Non-Hispanic Black86.3 (84.7, 87.7)13.7 (12.3, 15.3)74.2 (71.7, 76.6)24.1 (21.9, 26.4)1.7 (1.1, 2.6)0.63
Mexican American93.7 (91.8, 95.1)6.3 (4.9, 8.2)87.5 (83.9, 90.4)12.3 (9.4, 15.8)0.2 (0.1, 0.5)0.25
Total*87.5 (86.3, 88.6)12.5 (11.4, 13.7)76.6 (74.8, 78.4)21.6 (20.2, 23.2)1.7 (1.2, 2.5)
rs689453AGAAAGGG
Non-Hispanic White7.9 (6.7, 9.2)92.1 (90.8, 93.3)<0.0010.5 (0.2, 1.1)14.7 (12.7, 17.0)84.8 (82.4, 86.9)0.0050.23
Non-Hispanic Black5.1 (4.2, 6.2)94.9 (93.8, 95.8)0.4 (0.1, 1.1)9.5 (7.5, 11.9)90.2 (87.9, 92.1)0.25
Mexican American5.2 (3.8, 7.0)94.8 (93.0, 96.2)0.6 (0.3, 1.3)9.2 (7.1, 12.0)90.2 (87.0, 92.6)0.21
Total*7.0 (6.1, 8.1)93.0 (91.9, 93.9)0.4 (0.2, 0.9)13.2 (11.4, 15.1)86.4 (84.4, 88.2)

* Includes all U.S. race/ethnic groups.
† “other" race/ethnicity category was not included in chi-square tests.
‡ P-values from unweighted chi-square goodness-of-fit tests to test for deviations from Hardy-Weinberg (HW) proportions.

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By Age*

VariantAge (years)Allele
% (95% CI)
Chi-square
P-value
Genotype
% (95% CI)
Chi-square
P-value
rs10517CTCCCTTT
12-1985.7 (83.4, 87.8)14.3 (12.2, 16.6)0.89474.3 (70.3, 77.8)22.9 (19.2, 27.1)2.8 (1.4, 5.4)0.864
20-3986.7 (84.3, 88.7)13.3 (11.3, 15.7)75.2 (71.4, 78.7)22.9 (20.0, 26.1)1.9 (1.2, 3.0)
40-5986.3 (84.4, 88.1)13.7 (11.9, 15.6)74.7 (71.4, 77.8)23.2 (20.2, 26.6)2.0 (1.2, 3.6)
>=6086.6 (84.7, 88.3)13.4 (11.7, 15.3)75.5 (72.4, 78.4)22.2 (19.5, 25.2)2.3 (1.2, 4.1)
Total86.4 (85.1, 87.7)13.6 (12.3, 14.9)75.0 (73.0, 77.0)22.9 (21.4, 24.4)2.1 (1.5, 3.0)
rs1800566CTCCCTTT
12-1976.1 (72.2, 79.5)23.9 (20.5, 27.8)0.10857.5 (50.9, 63.9)37.1 (31.0, 43.6)5.4 (3.8, 7.6)0.185
20-3977.9 (75.5, 80.1)22.1 (19.9, 24.5)61.1 (57.2, 65.0)33.5 (30.1, 37.1)5.4 (4.3, 6.7)
40-5980.1 (77.3, 82.6)19.9 (17.4, 22.7)64.2 (59.3, 68.7)31.9 (27.5, 36.6)4.0 (2.8, 5.6)
>=6079.3 (77.1, 81.4)20.7 (18.6, 22.9)62.9 (59.2, 66.5)32.9 (29.5, 36.4)4.2 (3.2, 5.6)
Total78.5 (76.8, 80.2)21.5 (19.8, 23.2)61.8 (58.8, 64.7)33.4 (30.8, 36.2)4.8 (4.1, 5.6)
rs34755915AGAAAGGG
12-191.4 (0.7, 2.8)98.6 (97.2, 99.3)0.9690.0 (NA)2.7 (1.3, 5.6)97.3 (94.4, 98.7)0.976
20-391.4 (0.9, 2.2)98.6 (97.8, 99.1)0.0 (NA)2.8 (1.8, 4.4)97.2 (95.6, 98.2)
40-591.4 (0.9, 2.1)98.6 (97.9, 99.1)0.0 (NA)2.8 (1.8, 4.2)97.2 (95.8, 98.2)
>=601.5 (1.0, 2.4)98.5 (97.6, 99.0)0.2 (0.0, 1.5)2.7 (1.9, 3.9)97.1 (95.7, 98.0)
Total1.4 (1.1, 1.8)98.6 (98.2, 98.9)0.0 (0.0, 0.3)2.8 (2.2, 3.5)97.2 (96.5, 97.8)
rs689452CGCCCGGG
12-1986.9 (84.9, 88.7)13.1 (11.3, 15.1)0.92376.2 (72.8, 79.3)21.3 (17.9, 25.2)2.5 (1.2, 5.1)0.867
20-3987.6 (85.5, 89.5)12.4 (10.5, 14.5)76.6 (73.2, 79.7)22.0 (19.4, 24.7)1.4 (0.8, 2.5)
40-5987.4 (85.7, 89.0)12.6 (11.0, 14.3)76.6 (73.4, 79.5)21.7 (18.8, 25.0)1.7 (0.9, 3.2)
>=6087.6 (85.7, 89.3)12.4 (10.7, 14.3)77.1 (73.8, 80.1)21.1 (18.3, 24.3)1.8 (1.0, 3.2)
Total87.5 (86.3, 88.6)12.5 (11.4, 13.7)76.6 (74.8, 78.4)21.6 (20.2, 23.2)1.7 (1.2, 2.5)
rs689453AGAAAGGG
12-197.4 (5.2, 10.3)92.6 (89.7, 94.8)0.2050.8 (0.2, 2.5)13.2 (9.2, 18.6)86.0 (80.6, 90.1)0.090
20-396.2 (5.2, 7.5)93.8 (92.5, 94.8)0.3 (0.1, 1.0)11.8 (9.7, 14.3)87.9 (85.4, 89.9)
40-597.6 (6.5, 9.0)92.4 (91.0, 93.5)0.3 (0.1, 1.0)14.7 (12.6, 17.1)85.0 (82.5, 87.2)
>=607.5 (6.2, 9.0)92.5 (91.0, 93.8)0.7 (0.3, 1.4)13.6 (11.1, 16.6)85.7 (82.8, 88.2)
Total7.0 (6.1, 8.1)93.0 (91.9, 93.9)0.4 (0.2, 0.9)13.2 (11.4, 15.1)86.4 (84.4, 88.2)

* Includes all participants, regardless of race/ethnicity.

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By Sex*

VariantSexAllele
% (95% CI)
Chi-square
P-value
Genotype
% (95% CI)
Chi-square
P-value
rs10517CTCCCTTT
Male86.1 (84.2, 87.7)13.9 (12.3, 15.8)0.50074.1 (71.2, 76.9)23.8 (21.3, 26.5)2.0 (1.1, 3.6)0.696
Female86.8 (85.0, 88.4)13.2 (11.6, 15.0)75.8 (72.6, 78.8)22.0 (19.2, 25.0)2.2 (1.7, 2.9)
Total86.4 (85.1, 87.7)13.6 (12.3, 14.9)75.0 (73.0, 77.0)22.9 (21.4, 24.4)2.1 (1.5, 3.0)
rs1800566CTCCCTTT
Male78.7 (76.2, 81.0)21.3 (19.0, 23.8)0.77061.8 (57.5, 65.9)33.8 (29.8, 38.1)4.4 (3.2, 6.0)0.694
Female78.4 (76.7, 79.9)21.6 (20.1, 23.3)61.9 (59.0, 64.7)33.0 (30.3, 35.9)5.1 (4.3, 6.0)
Total78.5 (76.8, 80.2)21.5 (19.8, 23.2)61.8 (58.8, 64.7)33.4 (30.8, 36.2)4.8 (4.1, 5.6)
rs34755915AGAAAGGG
Male1.6 (1.2, 2.1)98.4 (97.9, 98.8)0.3200.0 (NA)3.1 (2.4, 4.2)96.9 (95.8, 97.6)0.206
Female1.3 (0.9, 1.8)98.7 (98.2, 99.1)0.1 (0.0, 0.5)2.4 (1.8, 3.3)97.5 (96.5, 98.2)
Total1.4 (1.1, 1.8)98.6 (98.2, 98.9)0.0 (0.0, 0.3)2.8 (2.2, 3.5)97.2 (96.5, 97.8)
rs689452CGCCCGGG
Male87.2 (85.5, 88.7)12.8 (11.3, 14.5)0.54576.0 (73.4, 78.5)22.3 (20.1, 24.6)1.7 (0.9, 3.1)0.815
Female87.8 (86.2, 89.2)12.2 (10.8, 13.8)77.2 (74.4, 79.9)21.1 (18.5, 23.9)1.7 (1.2, 2.5)
Total87.5 (86.3, 88.6)12.5 (11.4, 13.7)76.6 (74.8, 78.4)21.6 (20.2, 23.2)1.7 (1.2, 2.5)
rs689453AGAAAGGG
Male7.6 (6.2, 9.3)92.4 (90.7, 93.8)0.0860.6 (0.3, 1.5)13.9 (11.4, 16.9)85.4 (82.3, 88.1)0.252
Female6.5 (5.7, 7.3)93.5 (92.7, 94.3)0.3 (0.1, 0.6)12.4 (10.9, 14.1)87.3 (85.6, 88.9)
Total7.0 (6.1, 8.1)93.0 (91.9, 93.9)0.4 (0.2, 0.9)13.2 (11.4, 15.1)86.4 (84.4, 88.2)

* Includes all participants, regardless of race/ethnicity.

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By Race/Ethnicity and Age

VariantRace-ethnicityAge (years)Allele
% (95% CI)
Genotype
% (95% CI)
rs10517CTCCCTTT
Non-Hispanic White12-1985.9 (82.3, 88.9)14.1 (11.1, 17.7)74.5 (68.6, 79.5)23.0 (18.6, 28.1)2.6 (1.3, 5.0)
20-3986.7 (84.1, 89.0)13.3 (11.0, 15.9)74.8 (70.0, 79.1)23.8 (19.7, 28.5)1.4 (0.9, 2.1)
40-5987.0 (84.4, 89.2)13.0 (10.8, 15.6)76.0 (72.1, 79.6)22.0 (18.9, 25.4)2.0 (0.9, 4.4)
>=6087.3 (85.7, 88.8)12.7 (11.2, 14.3)76.4 (73.4, 79.1)22.0 (19.2, 24.9)1.7 (0.9, 3.1)
Non-Hispanic Black12-1985.9 (82.8, 88.5)14.1 (11.5, 17.2)73.9 (68.6, 78.5)24.0 (19.3, 29.4)2.1 (0.8, 5.6)
20-3986.2 (84.1, 88.1)13.8 (11.9, 15.9)74.1 (70.4, 77.5)24.2 (20.8, 28.0)1.7 (0.8, 3.6)
40-5986.5 (84.2, 88.5)13.5 (11.5, 15.8)73.9 (69.7, 77.7)25.3 (21.7, 29.3)0.8 (0.3, 2.1)
>=6085.4 (81.5, 88.7)14.6 (11.3, 18.5)73.7 (66.5, 79.7)23.6 (17.6, 30.8)2.8 (1.4, 5.2)
Mexican American12-1994.5 (90.5, 96.8)5.5 (3.2, 9.5)89.5 (82.3, 94.0)9.9 (5.6, 16.8)0.6 (0.1, 2.6)
20-3993.8 (92.3, 95.1)6.2 (4.9, 7.7)87.7 (84.7, 90.1)12.3 (9.9, 15.3)0.0 (NA)
40-5992.2 (89.6, 94.2)7.8 (5.8, 10.4)84.5 (79.4, 88.4)15.4 (11.4, 20.5)0.1 (0.0, 1.0)
>=6092.5 (90.1, 94.4)7.5 (5.6, 9.9)85.9 (82.0, 89.1)13.2 (10.3, 16.8)0.8 (0.2, 3.4)
rs1800566CTCCCTTT
Non-Hispanic White12-1978.1 (73.4, 82.1)21.9 (17.9, 26.6)60.2 (52.4, 67.5)35.7 (28.9, 43.2)4.1 (2.1, 7.6)
20-3980.9 (78.1, 83.3)19.1 (16.7, 21.9)64.6 (59.6, 69.3)32.5 (28.1, 37.2)2.9 (2.2, 3.9)
40-5981.4 (78.0, 84.4)18.6 (15.6, 22.0)66.8 (60.8, 72.3)29.1 (23.8, 35.0)4.1 (2.7, 6.1)
>=6080.6 (78.0, 83.0)19.4 (17.0, 22.0)64.5 (60.0, 68.7)32.2 (28.5, 36.2)3.3 (2.4, 4.6)
Non-Hispanic Black12-1982.5 (80.2, 84.5)17.5 (15.5, 19.8)67.8 (63.6, 71.8)29.2 (24.6, 34.3)2.9 (1.5, 5.6)
20-3979.4 (77.6, 81.2)20.6 (18.8, 22.4)63.1 (59.7, 66.3)32.7 (29.2, 36.4)4.2 (3.0, 6.0)
40-5982.8 (79.5, 85.7)17.2 (14.3, 20.5)68.1 (62.2, 73.4)29.5 (24.4, 35.1)2.5 (1.4, 4.4)
>=6081.9 (78.6, 84.7)18.1 (15.3, 21.4)67.6 (62.6, 72.3)28.5 (24.1, 33.3)3.9 (2.1, 7.0)
Mexican American12-1960.6 (56.1, 64.9)39.4 (35.1, 43.9)39.4 (32.9, 46.3)42.3 (35.5, 49.4)18.3 (14.4, 22.9)
20-3964.5 (62.3, 66.7)35.5 (33.3, 37.7)42.4 (39.3, 45.6)44.3 (41.5, 47.2)13.3 (11.5, 15.3)
40-5961.9 (58.8, 64.8)38.1 (35.2, 41.2)36.2 (31.6, 41.1)51.4 (45.4, 57.2)12.4 (9.3, 16.5)
>=6064.7 (60.8, 68.4)35.3 (31.6, 39.2)41.5 (35.7, 47.6)46.4 (40.5, 52.4)12.1 (9.2, 15.9)
rs34755915AGAAAGGG
Non-Hispanic White12-192.0 (0.9, 4.2)98.0 (95.8, 99.1)0.0 (NA)4.0 (1.9, 8.4)96.0 (91.6, 98.1)
20-391.8 (1.2, 2.8)98.2 (97.2, 98.8)0.0 (NA)3.7 (2.4, 5.6)96.3 (94.4, 97.6)
40-591.7 (1.1, 2.6)98.3 (97.4, 98.9)0.0 (NA)3.4 (2.2, 5.3)96.6 (94.7, 97.8)
>=601.8 (1.2, 2.8)98.2 (97.2, 98.8)0.2 (0.0, 1.8)3.2 (2.3, 4.5)96.6 (95.0, 97.7)
Non-Hispanic Black12-190.1 (0.0, 0.7)99.9 (99.3, 100.0)0.0 (NA)0.2 (0.0, 1.4)99.8 (98.6, 100.0)
20-390.6 (0.2, 1.7)99.4 (98.3, 99.8)0.0 (NA)1.2 (0.4, 3.3)98.8 (96.7, 99.6)
40-590.3 (0.1, 1.0)99.7 (99.0, 99.9)0.0 (NA)0.7 (0.2, 2.0)99.3 (98.0, 99.8)
>=600.3 (0.1, 1.4)99.7 (98.6, 99.9)0.0 (NA)0.6 (0.2, 2.7)99.4 (97.3, 99.8)
Mexican American12-190.5 (0.1, 2.2)99.5 (97.8, 99.9)0.0 (NA)1.0 (0.2, 4.3)99.0 (95.7, 99.8)
20-390.6 (0.3, 1.2)99.4 (98.8, 99.7)0.0 (NA)1.2 (0.6, 2.3)98.8 (97.7, 99.4)
40-590.5 (0.2, 1.6)99.5 (98.4, 99.8)0.0 (NA)1.0 (0.3, 3.2)99.0 (96.8, 99.7)
>=600.5 (0.2, 1.3)99.5 (98.7, 99.8)0.0 (NA)0.9 (0.3, 2.7)99.1 (97.3, 99.7)
rs689452CGCCCGGG
Non-Hispanic White12-1987.3 (84.0, 90.0)12.7 (10.0, 16.0)76.6 (71.3, 81.2)21.3 (17.2, 26.1)2.0 (0.9, 4.5)
20-3988.0 (85.5, 90.1)12.0 (9.9, 14.5)77.0 (72.4, 80.9)22.1 (18.3, 26.3)1.0 (0.5, 1.8)
40-5988.3 (86.0, 90.2)11.7 (9.8, 14.0)78.1 (74.5, 81.4)20.3 (17.3, 23.7)1.6 (0.6, 4.1)
>=6088.5 (86.8, 90.0)11.5 (10.0, 13.2)78.2 (75.0, 81.1)20.5 (17.7, 23.7)1.2 (0.7, 2.3)
Non-Hispanic Black12-1985.7 (82.6, 88.3)14.3 (11.7, 17.4)73.6 (68.3, 78.2)24.3 (19.6, 29.7)2.1 (0.8, 5.7)
20-3986.3 (84.4, 87.9)13.7 (12.1, 15.6)74.2 (70.8, 77.3)24.2 (20.9, 27.8)1.6 (0.8, 3.5)
40-5986.9 (84.5, 89.0)13.1 (11.0, 15.5)74.7 (70.3, 78.6)24.5 (20.7, 28.6)0.8 (0.3, 2.1)
>=6085.8 (81.8, 89.1)14.2 (10.9, 18.2)74.4 (67.0, 80.5)22.9 (16.9, 30.2)2.8 (1.4, 5.2)
Mexican American12-1994.6 (90.8, 96.9)5.4 (3.1, 9.2)89.9 (82.9, 94.2)9.5 (5.4, 16.1)0.6 (0.1, 2.6)
20-3993.9 (92.2, 95.3)6.1 (4.7, 7.8)87.8 (84.4, 90.6)12.2 (9.4, 15.6)0.0 (NA)
40-5992.4 (89.9, 94.4)7.6 (5.6, 10.1)85.0 (80.1, 88.9)14.9 (11.0, 19.8)0.1 (0.0, 1.0)
>=6092.8 (90.0, 94.8)7.2 (5.2, 10.0)86.4 (81.7, 90.1)12.7 (9.3, 17.1)0.8 (0.2, 3.4)
rs689453AGAAAGGG
Non-Hispanic White12-198.6 (5.5, 13.0)91.4 (87.0, 94.5)1.1 (0.3, 3.8)14.9 (9.3, 23.0)84.0 (75.8, 89.8)
20-396.9 (5.6, 8.5)93.1 (91.5, 94.4)0.4 (0.1, 1.3)13.1 (10.5, 16.2)86.5 (83.5, 89.1)
40-598.5 (7.0, 10.4)91.5 (89.6, 93.0)0.3 (0.1, 1.5)16.5 (13.8, 19.8)83.2 (79.8, 86.1)
>=608.2 (6.7, 10.0)91.8 (90.0, 93.3)0.7 (0.3, 1.6)15.0 (12.0, 18.5)84.3 (80.9, 87.2)
Non-Hispanic Black12-195.5 (4.1, 7.3)94.5 (92.7, 95.9)0.3 (0.1, 1.1)10.4 (7.6, 14.0)89.3 (85.8, 92.1)
20-394.3 (3.3, 5.5)95.7 (94.5, 96.7)0.2 (0.0, 0.7)8.2 (6.3, 10.8)91.6 (89.1, 93.6)
40-595.3 (3.8, 7.5)94.7 (92.5, 96.2)0.5 (0.1, 3.6)9.7 (6.6, 14.1)89.8 (85.7, 92.9)
>=606.6 (4.7, 9.2)93.4 (90.8, 95.3)0.8 (0.2, 3.4)11.5 (7.5, 17.1)87.7 (82.5, 91.5)
Mexican American12-195.0 (2.7, 9.1)95.0 (90.9, 97.3)0.0 (NA)10.1 (5.4, 18.0)89.9 (82.0, 94.6)
20-395.5 (4.0, 7.5)94.5 (92.5, 96.0)0.7 (0.3, 1.8)9.5 (7.1, 12.6)89.8 (86.3, 92.5)
40-595.6 (4.0, 7.8)94.4 (92.2, 96.0)0.8 (0.2, 3.1)9.5 (6.6, 13.6)89.7 (85.7, 92.6)
>=603.1 (2.5, 3.9)96.9 (96.1, 97.5)0.6 (0.1, 3.8)5.0 (3.2, 7.8)94.4 (92.7, 95.7)

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By Race/Ethnicity and Sex

VariantRace-ethnicitySexAllele
% (95% CI)
Genotype
% (95% CI)
rs10517CTCCCTTT
Non-Hispanic WhiteMale86.6 (84.8, 88.1)13.4 (11.9, 15.2)74.5 (71.0, 77.8)24.1 (20.6, 28.0)1.4 (0.8, 2.5)
Female87.1 (85.1, 88.8)12.9 (11.2, 14.9)76.3 (73.0, 79.4)21.5 (18.8, 24.5)2.1 (1.4, 3.2)
Non-Hispanic BlackMale85.2 (82.9, 87.2)14.8 (12.8, 17.1)72.0 (67.9, 75.8)26.3 (22.7, 30.3)1.7 (0.9, 3.2)
Female86.9 (84.5, 89.0)13.1 (11.0, 15.5)75.5 (71.6, 79.1)22.7 (19.5, 26.3)1.7 (0.8, 3.7)
Mexican AmericanMale93.8 (91.2, 95.7)6.2 (4.3, 8.8)87.7 (82.6, 91.5)12.2 (8.4, 17.3)0.1 (0.0, 0.7)
Female93.2 (91.5, 94.5)6.8 (5.5, 8.5)86.7 (83.5, 89.3)13.0 (10.4, 16.1)0.3 (0.1, 0.8)
rs1800566CTCCCTTT
Non-Hispanic WhiteMale81.2 (78.7, 83.4)18.8 (16.6, 21.3)65.1 (60.3, 69.6)32.2 (27.6, 37.3)2.7 (1.8, 4.2)
Female80.1 (78.0, 82.0)19.9 (18.0, 22.0)64.3 (60.8, 67.7)31.5 (28.2, 35.0)4.2 (3.1, 5.7)
Non-Hispanic BlackMale80.6 (78.0, 82.9)19.4 (17.1, 22.0)65.2 (61.6, 68.5)30.9 (28.0, 33.9)4.0 (2.3, 6.8)
Female81.6 (80.4, 82.8)18.4 (17.2, 19.6)66.4 (64.3, 68.5)30.5 (28.5, 32.6)3.1 (2.5, 3.9)
Mexican AmericanMale62.1 (59.6, 64.6)37.9 (35.4, 40.4)38.8 (35.6, 42.1)46.7 (43.7, 49.7)14.5 (12.1, 17.3)
Female64.3 (61.8, 66.7)35.7 (33.3, 38.2)42.1 (38.2, 46.0)44.4 (40.8, 48.2)13.5 (11.7, 15.5)
rs34755915AGAAAGGG
Non-Hispanic WhiteMale2.0 (1.5, 2.6)98.0 (97.4, 98.5)0.0 (NA)4.0 (3.0, 5.3)96.0 (94.7, 97.0)
Female1.7 (1.2, 2.3)98.3 (97.7, 98.8)0.1 (0.0, 0.7)3.1 (2.3, 4.2)96.8 (95.6, 97.6)
Non-Hispanic BlackMale0.5 (0.2, 1.3)99.5 (98.7, 99.8)0.0 (NA)0.9 (0.4, 2.5)99.1 (97.5, 99.6)
Female0.3 (0.2, 0.7)99.7 (99.3, 99.8)0.0 (NA)0.7 (0.3, 1.4)99.3 (98.6, 99.7)
Mexican AmericanMale0.6 (0.3, 1.3)99.4 (98.7, 99.7)0.0 (NA)1.3 (0.6, 2.5)98.7 (97.5, 99.4)
Female0.4 (0.3, 0.7)99.6 (99.3, 99.7)0.0 (NA)0.9 (0.5, 1.4)99.1 (98.6, 99.5)
rs689452CGCCCGGG
Non-Hispanic WhiteMale87.9 (86.1, 89.4)12.1 (10.6, 13.9)76.9 (73.4, 80.0)22.0 (18.8, 25.5)1.2 (0.7, 2.0)
Female88.3 (86.6, 89.8)11.7 (10.2, 13.4)78.2 (75.2, 80.9)20.3 (17.8, 23.1)1.5 (0.9, 2.6)
Non-Hispanic BlackMale85.1 (82.7, 87.3)14.9 (12.7, 17.3)72.0 (67.6, 75.9)26.4 (22.5, 30.6)1.7 (0.9, 3.2)
Female87.2 (84.8, 89.3)12.8 (10.7, 15.2)76.1 (72.2, 79.6)22.2 (19.1, 25.7)1.7 (0.8, 3.6)
Mexican AmericanMale93.8 (91.2, 95.7)6.2 (4.3, 8.8)87.8 (82.6, 91.6)12.1 (8.4, 17.3)0.1 (0.0, 0.7)
Female93.5 (91.7, 94.9)6.5 (5.1, 8.3)87.3 (83.8, 90.1)12.4 (9.6, 15.9)0.3 (0.1, 0.8)
rs689453AGAAAGGG
Non-Hispanic WhiteMale8.7 (7.0, 10.8)91.3 (89.2, 93.0)0.8 (0.3, 1.8)15.9 (12.9, 19.5)83.3 (79.5, 86.5)
Female7.0 (6.2, 8.0)93.0 (92.0, 93.8)0.3 (0.1, 0.7)13.6 (11.8, 15.5)86.2 (84.2, 87.9)
Non-Hispanic BlackMale4.5 (3.4, 5.9)95.5 (94.1, 96.6)0.2 (0.0, 1.0)8.5 (6.2, 11.6)91.3 (88.3, 93.6)
Female5.6 (4.4, 7.0)94.4 (93.0, 95.6)0.5 (0.1, 1.4)10.2 (7.8, 13.3)89.3 (86.4, 91.6)
Mexican AmericanMale5.3 (3.6, 7.6)94.7 (92.4, 96.4)0.9 (0.3, 2.4)8.7 (6.2, 12.1)90.4 (86.5, 93.3)
Female5.2 (3.9, 6.7)94.8 (93.3, 96.1)0.3 (0.1, 1.1)9.8 (7.5, 12.7)89.9 (87.0, 92.3)


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