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U.S. Genome Variation Estimates

NAT2 Allele and Genotype Frequencies

Available polymorphism(s)

rs number

Common Designations

Nucleotide change Amino acid

Genotyping method

rs1041983

Ex2+288C>T

Tyr94Tyr

TaqMan

rs1208

Ex2-367A>G

Lys268Arg

TaqMan

rs1799930

Ex2-580G>A

Arg197Gln

TaqMan

rs1801279

Ex2+197G>A

Arg64Gln

TaqMan

rs1801280

Ex2+347T>C

Ile114Thr

TaqMan




Allele and Genotype Frequencies for Subpopulations


By Race/Ethnicity

VariantRace-ethnicityAllele
% (95% CI)
Chi-square
P-value†
Genotype
% (95% CI)
Chi-square
P-value†
HW
P-value‡
rs1041983CTCCCTTT
Non-Hispanic White64.6 (62.9, 66.2)35.4 (33.8, 37.1)<0.00141.4 (38.9, 43.9)46.3 (43.8, 48.9)12.3 (10.8, 13.8)<0.0010.77
Non-Hispanic Black53.9 (52.4, 55.4)46.1 (44.6, 47.6)30.8 (28.9, 32.8)46.2 (43.8, 48.5)23.0 (21.2, 24.9)0.03
Mexican American68.1 (65.6, 70.6)31.9 (29.4, 34.4)46.7 (43.4, 50.1)42.8 (40.1, 45.6)10.5 (8.4, 12.9)0.66
Total*63.6 (62.1, 65.0)36.4 (35.0, 37.9)40.4 (38.4, 42.4)46.3 (44.6, 48.1)13.3 (12.0, 14.7)
rs1208AGAAAGGG
Non-Hispanic White59.0 (57.7, 60.1)41.0 (39.9, 42.3)<0.00134.5 (33.1, 36.0)48.9 (47.3, 50.4)16.6 (15.2, 18.1)<0.0010.67
Non-Hispanic Black61.7 (60.3, 63.1)38.3 (36.9, 39.7)39.3 (37.3, 41.2)44.9 (42.7, 47.2)15.8 (14.2, 17.5)0.06
Mexican American64.3 (62.1, 66.5)35.7 (33.5, 37.9)41.2 (38.2, 44.4)46.2 (43.5, 48.9)12.6 (10.8, 14.6)0.68
Total*60.6 (59.8, 61.5)39.4 (38.5, 40.2)37.2 (35.9, 38.5)46.8 (45.4, 48.2)15.9 (15.1, 16.8)
rs1799930AGAAAGGG
Non-Hispanic White32.3 (30.5, 34.1)67.7 (65.9, 69.5)<0.00110.1 (8.7, 11.7)44.4 (42.0, 46.7)45.5 (42.8, 48.2)<0.0010.83
Non-Hispanic Black28.0 (25.8, 30.3)72.0 (69.7, 74.2)8.7 (7.1, 10.5)38.6 (35.6, 41.8)52.7 (49.2, 56.2)0.04
Mexican American18.0 (16.0, 20.1)82.0 (79.9, 84.0)3.2 (2.2, 4.7)29.5 (26.0, 33.2)67.3 (63.5, 70.9)0.70
Total*30.2 (28.9, 31.5)69.8 (68.5, 71.1)8.9 (7.9, 10.1)42.6 (40.8, 44.5)48.5 (46.5, 50.5)
rs1801279AGAAAGGG
Non-Hispanic White0.0 (0.0, 0.1)100.0 (99.9, 100.0)<0.0010.0 (NA)0.1 (0.0, 0.3)99.9 (99.7, 100.0)<0.0010.97
Non-Hispanic Black7.8 (6.9, 8.8)92.2 (91.2, 93.1)0.4 (0.2, 0.9)14.9 (13.1, 16.8)84.7 (82.8, 86.5)0.05
Mexican American0.5 (0.3, 0.9)99.5 (99.1, 99.7)0.0 (0.0, 0.1)1.0 (0.6, 1.8)99.0 (98.2, 99.4)<0.01
Total*1.0 (0.8, 1.3)99.0 (98.7, 99.2)0.0 (0.0, 0.1)2.0 (1.5, 2.6)98.0 (97.4, 98.4)
rs1801280CTCCCTTT
Non-Hispanic White42.1 (40.9, 43.3)57.9 (56.7, 59.1)<0.00117.5 (15.9, 19.2)49.3 (47.4, 51.3)33.2 (31.8, 34.7)<0.0010.85
Non-Hispanic Black29.3 (27.7, 30.9)70.7 (69.1, 72.3)9.1 (7.8, 10.7)40.3 (37.5, 43.1)50.6 (48.0, 53.3)0.65
Mexican American32.4 (29.5, 35.3)67.6 (64.7, 70.5)10.1 (7.9, 12.9)44.4 (41.5, 47.4)45.4 (41.6, 49.3)0.60
Total*38.9 (37.8, 40.0)61.1 (60.0, 62.2)15.7 (14.5, 16.8)46.5 (44.7, 48.2)37.9 (36.2, 39.6)

* Includes all U.S. race/ethnic groups.
† “other" race/ethnicity category was not included in chi-square tests.
‡ P-values from unweighted chi-square goodness-of-fit tests to test for deviations from Hardy-Weinberg (HW) proportions.

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By Age*

VariantAge (years)Allele
% (95% CI)
Chi-square
P-value
Genotype
% (95% CI)
Chi-square
P-value
rs1041983CTCCCTTT
12-1962.6 (58.6, 66.5)37.4 (33.5, 41.4)0.84138.6 (33.5, 43.8)48.2 (42.1, 54.4)13.3 (9.1, 18.9)0.909
20-3963.3 (61.0, 65.5)36.7 (34.5, 39.0)40.3 (37.4, 43.3)45.9 (43.3, 48.6)13.7 (11.7, 16.1)
40-5963.9 (61.1, 66.6)36.1 (33.4, 38.9)40.2 (35.9, 44.7)47.4 (42.4, 52.4)12.4 (9.8, 15.6)
>=6064.3 (61.8, 66.7)35.7 (33.3, 38.2)42.2 (38.0, 46.5)44.2 (39.6, 48.8)13.6 (11.7, 15.8)
Total63.6 (62.1, 65.0)36.4 (35.0, 37.9)40.4 (38.4, 42.4)46.3 (44.6, 48.1)13.3 (12.0, 14.7)
rs1208AGAAAGGG
12-1961.2 (57.6, 64.8)38.8 (35.2, 42.4)0.87638.2 (33.1, 43.6)46.1 (41.8, 50.5)15.7 (13.0, 18.8)0.989
20-3960.6 (58.5, 62.7)39.4 (37.3, 41.5)37.3 (33.6, 41.1)46.7 (42.4, 51.0)16.1 (14.3, 18.0)
40-5960.9 (59.1, 62.7)39.1 (37.3, 40.9)37.1 (34.1, 40.3)47.5 (42.9, 52.2)15.3 (12.7, 18.3)
>=6059.9 (57.8, 62.0)40.1 (38.0, 42.2)36.6 (34.5, 38.7)46.6 (44.2, 49.1)16.8 (14.2, 19.7)
Total60.6 (59.8, 61.5)39.4 (38.5, 40.2)37.2 (35.9, 38.5)46.8 (45.4, 48.2)15.9 (15.1, 16.8)
rs1799930AGAAAGGG
12-1930.2 (26.7, 34.1)69.8 (65.9, 73.3)0.8238.7 (6.1, 12.4)43.0 (38.0, 48.2)48.2 (42.7, 53.8)0.574
20-3929.6 (27.5, 31.9)70.4 (68.1, 72.5)8.9 (7.1, 11.1)41.5 (38.7, 44.3)49.6 (46.5, 52.8)
40-5930.5 (28.3, 32.8)69.5 (67.2, 71.7)8.1 (6.0, 11.0)44.7 (40.1, 49.4)47.1 (43.3, 50.9)
>=6030.9 (29.2, 32.7)69.1 (67.3, 70.8)10.2 (8.6, 12.1)41.5 (37.4, 45.7)48.3 (45.0, 51.7)
Total30.2 (28.9, 31.5)69.8 (68.5, 71.1)8.9 (7.9, 10.1)42.6 (40.8, 44.5)48.5 (46.5, 50.5)
rs1801279AGAAAGGG
12-191.3 (0.9, 1.9)98.7 (98.1, 99.1)0.1470.1 (0.0, 0.7)2.4 (1.7, 3.3)97.5 (96.4, 98.3)0.197
20-391.1 (0.8, 1.6)98.9 (98.4, 99.2)0.1 (0.0, 0.2)2.1 (1.4, 3.0)97.9 (97.0, 98.5)
40-591.1 (0.8, 1.5)98.9 (98.5, 99.2)0.0 (0.0, 0.2)2.1 (1.5, 3.0)97.9 (97.0, 98.5)
>=600.7 (0.4, 1.1)99.3 (98.9, 99.6)0.0 (0.0, 0.1)1.3 (0.8, 2.1)98.7 (97.9, 99.1)
Total1.0 (0.8, 1.3)99.0 (98.7, 99.2)0.0 (0.0, 0.1)2.0 (1.5, 2.6)98.0 (97.4, 98.4)
rs1801280CTCCCTTT
12-1937.6 (34.3, 41.0)62.4 (59.0, 65.7)0.54013.4 (10.5, 16.9)48.5 (43.4, 53.6)38.2 (33.3, 43.3)0.591
20-3938.7 (36.2, 41.2)61.3 (58.8, 63.8)15.7 (13.8, 17.7)46.0 (42.3, 49.8)38.3 (34.5, 42.3)
40-5938.7 (37.0, 40.5)61.3 (59.5, 63.0)15.3 (12.6, 18.5)46.8 (42.5, 51.1)37.9 (35.4, 40.5)
>=6040.5 (37.9, 43.1)59.5 (56.9, 62.1)17.8 (14.8, 21.2)45.4 (42.2, 48.6)36.8 (34.0, 39.8)
Total38.9 (37.8, 40.0)61.1 (60.0, 62.2)15.7 (14.5, 16.8)46.5 (44.7, 48.2)37.9 (36.2, 39.6)

* Includes all participants, regardless of race/ethnicity.

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By Sex*

VariantSexAllele
% (95% CI)
Chi-square
P-value
Genotype
% (95% CI)
Chi-square
P-value
rs1041983CTCCCTTT
Male64.1 (62.1, 66.0)35.9 (34.0, 37.9)0.23941.2 (38.8, 43.6)45.8 (43.9, 47.7)13.0 (11.2, 15.1)0.419
Female63.1 (61.6, 64.6)36.9 (35.4, 38.4)39.7 (37.5, 41.9)46.8 (44.6, 48.9)13.5 (12.2, 15.0)
Total63.6 (62.1, 65.0)36.4 (35.0, 37.9)40.4 (38.4, 42.4)46.3 (44.6, 48.1)13.3 (12.0, 14.7)
rs1208AGAAAGGG
Male59.8 (58.2, 61.3)40.2 (38.7, 41.8)0.10835.8 (33.6, 38.1)47.8 (45.2, 50.5)16.3 (14.6, 18.2)0.245
Female61.5 (60.2, 62.7)38.5 (37.3, 39.8)38.5 (36.6, 40.5)45.9 (43.5, 48.4)15.6 (14.1, 17.1)
Total60.6 (59.8, 61.5)39.4 (38.5, 40.2)37.2 (35.9, 38.5)46.8 (45.4, 48.2)15.9 (15.1, 16.8)
rs1799930AGAAAGGG
Male29.7 (28.0, 31.4)70.3 (68.6, 72.0)0.1548.2 (7.0, 9.6)42.9 (40.5, 45.3)48.9 (46.3, 51.5)0.128
Female30.7 (29.4, 32.0)69.3 (68.0, 70.6)9.5 (8.4, 10.9)42.3 (40.0, 44.7)48.1 (46.0, 50.3)
Total30.2 (28.9, 31.5)69.8 (68.5, 71.1)8.9 (7.9, 10.1)42.6 (40.8, 44.5)48.5 (46.5, 50.5)
rs1801279AGAAAGGG
Male0.9 (0.7, 1.1)99.1 (98.9, 99.3)0.0530.0 (0.0, 0.2)1.7 (1.3, 2.2)98.3 (97.8, 98.7)0.191
Female1.2 (0.9, 1.6)98.8 (98.4, 99.1)0.1 (0.0, 0.2)2.3 (1.6, 3.2)97.7 (96.8, 98.3)
Total1.0 (0.8, 1.3)99.0 (98.7, 99.2)0.0 (0.0, 0.1)2.0 (1.5, 2.6)98.0 (97.4, 98.4)
rs1801280CTCCCTTT
Male39.8 (38.1, 41.6)60.2 (58.4, 61.9)0.09216.2 (14.5, 18.0)47.2 (44.7, 49.8)36.6 (34.1, 39.2)0.281
Female38.0 (36.7, 39.4)62.0 (60.6, 63.3)15.2 (13.8, 16.7)45.7 (43.1, 48.4)39.1 (36.9, 41.4)
Total38.9 (37.8, 40.0)61.1 (60.0, 62.2)15.7 (14.5, 16.8)46.5 (44.7, 48.2)37.9 (36.2, 39.6)

* Includes all participants, regardless of race/ethnicity.

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By Race/Ethnicity and Age

VariantRace-ethnicityAge (years)Allele
% (95% CI)
Genotype
% (95% CI)
rs1041983CTCCCTTT
Non-Hispanic White12-1962.6 (58.1, 66.9)37.4 (33.1, 41.9)37.4 (29.6, 46.0)50.3 (39.5, 61.2)12.2 (7.7, 18.9)
20-3964.5 (61.9, 67.1)35.5 (32.9, 38.1)41.7 (38.3, 45.2)45.7 (42.4, 49.0)12.6 (10.1, 15.6)
40-5965.1 (61.7, 68.3)34.9 (31.7, 38.3)41.5 (36.7, 46.5)47.1 (41.6, 52.6)11.4 (8.2, 15.7)
>=6065.1 (62.3, 67.7)34.9 (32.3, 37.7)42.9 (38.2, 47.8)44.2 (39.1, 49.5)12.8 (10.8, 15.2)
Non-Hispanic Black12-1953.8 (48.4, 59.1)46.2 (40.9, 51.6)30.6 (24.8, 37.2)46.3 (41.6, 51.1)23.1 (18.0, 29.0)
20-3953.6 (51.7, 55.6)46.4 (44.4, 48.3)30.5 (28.1, 32.9)46.3 (43.1, 49.7)23.2 (20.6, 26.0)
40-5954.2 (49.5, 58.8)45.8 (41.2, 50.5)31.1 (25.8, 36.8)46.2 (41.8, 50.7)22.7 (18.3, 27.9)
>=6054.5 (47.9, 60.9)45.5 (39.1, 52.1)31.8 (24.8, 39.8)45.3 (38.6, 52.2)22.9 (16.4, 30.9)
Mexican American12-1969.8 (64.0, 75.0)30.2 (25.0, 36.0)50.6 (42.2, 58.9)38.4 (30.3, 47.2)11.0 (6.9, 17.1)
20-3968.1 (64.9, 71.1)31.9 (28.9, 35.1)46.8 (42.5, 51.2)42.6 (38.8, 46.4)10.6 (8.1, 13.7)
40-5967.8 (63.9, 71.4)32.2 (28.6, 36.1)44.9 (39.2, 50.7)45.7 (40.2, 51.3)9.4 (6.7, 13.0)
>=6065.1 (61.7, 68.4)34.9 (31.6, 38.3)41.6 (35.6, 47.8)47.2 (40.6, 53.8)11.3 (8.9, 14.2)
rs1208AGAAAGGG
Non-Hispanic White12-1960.4 (56.5, 64.2)39.6 (35.8, 43.5)36.4 (30.3, 43.0)48.1 (41.3, 54.8)15.5 (12.3, 19.4)
20-3958.5 (55.4, 61.6)41.5 (38.4, 44.6)33.5 (28.6, 38.9)49.9 (44.9, 55.0)16.5 (14.3, 19.0)
40-5958.7 (55.9, 61.5)41.3 (38.5, 44.1)34.3 (30.2, 38.7)48.8 (42.8, 54.9)16.9 (13.2, 21.2)
>=6059.2 (56.8, 61.5)40.8 (38.5, 43.2)35.4 (33.5, 37.4)47.5 (44.6, 50.4)17.1 (14.0, 20.7)
Non-Hispanic Black12-1961.8 (56.4, 67.0)38.2 (33.0, 43.6)40.0 (33.7, 46.6)43.7 (39.3, 48.2)16.3 (12.0, 21.8)
20-3961.7 (59.6, 63.7)38.3 (36.3, 40.4)40.0 (36.7, 43.3)43.4 (39.6, 47.3)16.6 (14.4, 19.0)
40-5962.2 (58.8, 65.4)37.8 (34.6, 41.2)39.3 (34.5, 44.2)45.8 (40.7, 51.0)14.9 (11.8, 18.7)
>=6060.9 (56.3, 65.4)39.1 (34.6, 43.7)36.1 (29.2, 43.6)49.7 (41.8, 57.6)14.2 (10.3, 19.4)
Mexican American12-1964.8 (60.6, 68.7)35.2 (31.3, 39.4)40.9 (36.5, 45.6)47.6 (41.0, 54.3)11.4 (6.8, 18.7)
20-3963.2 (59.9, 66.5)36.8 (33.5, 40.1)39.7 (34.7, 45.0)47.0 (42.5, 51.6)13.3 (11.0, 15.9)
40-5967.3 (65.0, 69.5)32.7 (30.5, 35.0)44.8 (40.1, 49.5)45.1 (38.9, 51.4)10.2 (7.7, 13.3)
>=6062.3 (56.6, 67.7)37.7 (32.3, 43.4)42.1 (36.8, 47.5)40.5 (35.0, 46.3)17.4 (11.5, 25.6)
rs1799930AGAAAGGG
Non-Hispanic White12-1933.7 (28.9, 38.9)66.3 (61.1, 71.1)10.7 (7.1, 15.8)46.0 (37.2, 55.1)43.3 (35.0, 52.0)
20-3932.4 (29.7, 35.3)67.6 (64.7, 70.3)10.4 (8.0, 13.5)44.0 (40.6, 47.4)45.6 (41.9, 49.4)
40-5931.8 (29.1, 34.6)68.2 (65.4, 70.9)9.0 (6.3, 12.7)45.5 (39.9, 51.3)45.4 (40.8, 50.1)
>=6032.0 (30.0, 34.1)68.0 (65.9, 70.0)10.7 (8.9, 12.9)42.6 (38.1, 47.2)46.7 (42.9, 50.5)
Non-Hispanic Black12-1928.1 (23.3, 33.5)71.9 (66.5, 76.7)9.8 (6.6, 14.5)36.6 (30.8, 42.9)53.6 (46.1, 60.9)
20-3927.9 (25.3, 30.7)72.1 (69.3, 74.7)8.9 (6.7, 11.6)38.1 (35.5, 40.9)53.0 (49.5, 56.5)
40-5926.9 (23.1, 31.1)73.1 (68.9, 76.9)6.2 (4.4, 8.6)41.4 (34.2, 49.0)52.4 (44.9, 59.7)
>=6029.8 (25.4, 34.6)70.2 (65.4, 74.6)10.9 (6.9, 16.8)37.8 (30.7, 45.5)51.3 (44.6, 58.0)
Mexican American12-1916.8 (13.1, 21.3)83.2 (78.7, 86.9)3.2 (1.7, 5.8)27.3 (20.5, 35.2)69.6 (61.5, 76.6)
20-3917.8 (15.6, 20.2)82.2 (79.8, 84.4)2.9 (1.6, 5.3)29.8 (25.7, 34.2)67.3 (63.1, 71.2)
40-5918.2 (14.9, 22.0)81.8 (78.0, 85.1)3.4 (1.5, 7.5)29.6 (24.2, 35.6)67.0 (60.9, 72.7)
>=6021.0 (17.1, 25.6)79.0 (74.4, 82.9)4.7 (2.8, 7.6)32.6 (25.0, 41.3)62.7 (54.3, 70.3)
rs1801279AGAAAGGG
Non-Hispanic White12-190.0 (NA)100.0 (NA)0.0 (NA)0.0 (NA)100.0 (NA)
20-390.0 (NA)100.0 (NA)0.0 (NA)0.0 (NA)100.0 (NA)
40-590.1 (0.0, 0.5)99.9 (99.5, 100.0)0.0 (NA)0.1 (0.0, 1.0)99.9 (99.0, 100.0)
>=600.1 (0.0, 0.3)99.9 (99.7, 100.0)0.0 (NA)0.2 (0.1, 0.7)99.8 (99.3, 99.9)
Non-Hispanic Black12-197.7 (5.3, 11.2)92.3 (88.8, 94.7)0.6 (0.1, 3.9)14.3 (10.6, 19.0)85.1 (79.5, 89.4)
20-397.8 (6.6, 9.3)92.2 (90.7, 93.4)0.4 (0.1, 1.5)14.8 (12.4, 17.5)84.8 (82.1, 87.2)
40-598.6 (6.9, 10.6)91.4 (89.4, 93.1)0.2 (0.0, 1.5)16.7 (13.1, 21.0)83.1 (78.9, 86.6)
>=606.6 (5.4, 8.2)93.4 (91.8, 94.6)0.2 (0.0, 2.1)12.8 (10.1, 16.1)87.0 (83.8, 89.6)
Mexican American12-190.6 (0.2, 1.7)99.4 (98.3, 99.8)0.0 (NA)1.2 (0.5, 3.3)98.8 (96.7, 99.5)
20-390.4 (0.2, 0.9)99.6 (99.1, 99.8)0.0 (NA)0.7 (0.3, 1.8)99.3 (98.2, 99.7)
40-590.7 (0.3, 1.9)99.3 (98.1, 99.7)0.0 (NA)1.5 (0.5, 3.8)98.5 (96.2, 99.5)
>=600.5 (0.2, 1.2)99.5 (98.8, 99.8)0.1 (0.0, 0.7)0.8 (0.2, 3.6)99.1 (97.2, 99.7)
rs1801280CTCCCTTT
Non-Hispanic White12-1940.4 (36.7, 44.2)59.6 (55.8, 63.3)14.1 (10.1, 19.2)52.7 (45.2, 60.0)33.3 (27.5, 39.5)
20-3942.5 (39.3, 45.7)57.5 (54.3, 60.7)17.3 (14.8, 20.1)50.3 (46.3, 54.3)32.4 (28.0, 37.2)
40-5942.2 (39.4, 45.0)57.8 (55.0, 60.6)17.8 (14.1, 22.1)48.8 (43.6, 54.1)33.4 (29.8, 37.2)
>=6042.4 (39.6, 45.3)57.6 (54.7, 60.4)19.2 (15.6, 23.4)46.5 (42.8, 50.3)34.3 (31.5, 37.2)
Non-Hispanic Black12-1928.8 (24.4, 33.5)71.2 (66.5, 75.6)9.0 (6.1, 12.9)39.6 (34.7, 44.7)51.5 (44.9, 58.0)
20-3930.2 (28.3, 32.2)69.8 (67.8, 71.7)10.5 (8.3, 13.2)39.4 (35.9, 43.0)50.1 (47.2, 53.0)
40-5928.3 (25.7, 31.1)71.7 (68.9, 74.3)8.6 (6.3, 11.5)39.5 (33.9, 45.5)51.9 (46.9, 56.9)
>=6028.7 (25.8, 31.8)71.3 (68.2, 74.2)6.1 (3.0, 12.1)45.2 (36.4, 54.4)48.7 (42.3, 55.0)
Mexican American12-1932.1 (27.3, 37.4)67.9 (62.6, 72.7)9.1 (4.5, 17.5)46.1 (40.8, 51.5)44.8 (39.7, 50.0)
20-3933.2 (30.1, 36.6)66.8 (63.4, 69.9)10.7 (8.2, 13.8)45.1 (40.8, 49.6)44.2 (39.5, 49.1)
40-5930.1 (26.0, 34.6)69.9 (65.4, 74.0)8.5 (5.8, 12.3)43.2 (37.4, 49.1)48.3 (41.7, 55.0)
>=6033.5 (28.8, 38.5)66.5 (61.5, 71.2)13.8 (9.3, 19.8)39.3 (34.2, 44.7)46.9 (41.1, 52.7)

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By Race/Ethnicity and Sex

VariantRace-ethnicitySexAllele
% (95% CI)
Genotype
% (95% CI)
rs1041983CTCCCTTT
Non-Hispanic WhiteMale65.2 (63.3, 67.1)34.8 (32.9, 36.7)42.0 (39.4, 44.7)46.4 (43.7, 49.1)11.6 (9.7, 13.7)
Female63.9 (61.9, 65.9)36.1 (34.1, 38.1)40.8 (37.6, 44.1)46.2 (43.1, 49.4)12.9 (11.4, 14.7)
Non-Hispanic BlackMale53.6 (50.2, 56.9)46.4 (43.1, 49.8)31.1 (27.0, 35.5)45.0 (41.3, 48.9)23.9 (20.6, 27.5)
Female54.2 (52.6, 55.7)45.8 (44.3, 47.4)30.6 (28.7, 32.6)47.1 (44.4, 49.8)22.3 (20.2, 24.5)
Mexican AmericanMale67.7 (64.7, 70.6)32.3 (29.4, 35.3)45.6 (41.6, 49.8)44.2 (41.1, 47.3)10.2 (8.0, 12.8)
Female68.5 (65.8, 71.2)31.5 (28.8, 34.2)47.9 (44.1, 51.6)41.3 (37.7, 45.1)10.8 (8.4, 13.8)
rs1208AGAAAGGG
Non-Hispanic WhiteMale58.4 (56.5, 60.2)41.6 (39.8, 43.5)33.4 (30.5, 36.4)50.0 (46.7, 53.2)16.6 (14.8, 18.7)
Female59.5 (57.7, 61.3)40.5 (38.7, 42.3)35.6 (33.7, 37.6)47.8 (44.9, 50.7)16.6 (14.2, 19.4)
Non-Hispanic BlackMale61.9 (59.5, 64.4)38.1 (35.6, 40.5)39.9 (36.3, 43.7)44.1 (39.9, 48.3)16.0 (13.5, 18.9)
Female61.5 (59.9, 63.2)38.5 (36.8, 40.1)38.7 (36.4, 41.1)45.7 (43.3, 48.0)15.6 (14.0, 17.4)
Mexican AmericanMale64.7 (61.4, 67.9)35.3 (32.1, 38.6)41.4 (37.2, 45.6)46.7 (43.1, 50.4)11.9 (9.1, 15.5)
Female63.9 (61.6, 66.1)36.1 (33.9, 38.4)41.1 (37.8, 44.5)45.6 (42.7, 48.6)13.3 (11.6, 15.2)
rs1799930AGAAAGGG
Non-Hispanic WhiteMale31.7 (29.9, 33.6)68.3 (66.4, 70.1)9.2 (7.6, 11.0)45.1 (42.4, 47.8)45.7 (43.0, 48.5)
Female32.9 (30.7, 35.1)67.1 (64.9, 69.3)11.0 (9.4, 12.9)43.7 (40.7, 46.7)45.3 (42.0, 48.6)
Non-Hispanic BlackMale28.7 (25.4, 32.3)71.3 (67.7, 74.6)9.6 (7.5, 12.2)38.2 (33.5, 43.2)52.2 (46.6, 57.7)
Female27.4 (25.8, 29.0)72.6 (71.0, 74.2)7.9 (6.5, 9.6)38.9 (35.8, 42.1)53.2 (50.4, 55.9)
Mexican AmericanMale18.1 (16.2, 20.3)81.9 (79.7, 83.8)3.1 (1.8, 5.2)30.1 (26.7, 33.9)66.8 (63.2, 70.2)
Female17.8 (14.9, 21.1)82.2 (78.9, 85.1)3.4 (2.0, 5.7)28.8 (24.8, 33.1)67.8 (62.7, 72.6)
rs1801279AGAAAGGG
Non-Hispanic WhiteMale0.0 (0.0, 0.3)100.0 (99.7, 100.0)0.0 (NA)0.1 (0.0, 0.6)99.9 (99.4, 100.0)
Female0.0 (0.0, 0.1)100.0 (99.9, 100.0)0.0 (NA)0.1 (0.0, 0.3)99.9 (99.7, 100.0)
Non-Hispanic BlackMale7.5 (6.6, 8.5)92.5 (91.5, 93.4)0.3 (0.1, 1.6)14.4 (12.6, 16.4)85.3 (83.4, 87.1)
Female8.1 (6.9, 9.5)91.9 (90.5, 93.1)0.4 (0.1, 1.2)15.3 (12.8, 18.3)84.3 (81.4, 86.7)
Mexican AmericanMale0.5 (0.2, 1.2)99.5 (98.8, 99.8)0.0 (0.0, 0.1)1.1 (0.5, 2.4)98.9 (97.6, 99.5)
Female0.5 (0.2, 1.0)99.5 (99.0, 99.8)0.0 (NA)0.9 (0.4, 2.0)99.1 (98.0, 99.6)
rs1801280CTCCCTTT
Non-Hispanic WhiteMale42.5 (40.5, 44.5)57.5 (55.5, 59.5)17.5 (15.6, 19.6)50.0 (46.8, 53.3)32.5 (29.5, 35.6)
Female41.8 (40.0, 43.5)58.2 (56.5, 60.0)17.4 (15.0, 20.1)48.7 (45.6, 51.8)33.9 (31.9, 36.0)
Non-Hispanic BlackMale30.2 (28.1, 32.5)69.8 (67.5, 71.9)10.2 (8.7, 11.9)40.0 (36.2, 44.0)49.8 (46.0, 53.5)
Female28.5 (26.5, 30.5)71.5 (69.5, 73.5)8.2 (6.5, 10.4)40.4 (37.6, 43.3)51.3 (48.4, 54.2)
Mexican AmericanMale31.6 (28.2, 35.2)68.4 (64.8, 71.8)9.7 (7.0, 13.2)43.8 (41.1, 46.5)46.5 (42.2, 50.9)
Female33.2 (30.3, 36.2)66.8 (63.8, 69.7)10.6 (8.6, 13.1)45.1 (40.9, 49.4)44.3 (39.7, 48.9)


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