HuGENet™ Workshops
Knowledge synthesis in gene-environment interaction in cancer IARC-NCI-HuGENet meeting
Monday, May 18th through Wednesday, May 20th, 2009
IARC, Lyon
Agenda
| May 18, 2009 | |
|---|---|
| 9:30 am | Opening P. Boffetta, IARC; M. Khoury, CDC; D. Winn, NCI |
| Session I: | Causality in the context of environmental carcinogenesis (Chair: P. Boffetta, IARC) |
| 10:00 am | Reliable measurement of environmental exposure: collateral damage in the genomic revolution? C. Wild, IARC |
| 10:20am | Interpreting epidemiological evidence for the identification of environmental carcinogens. P. Boffetta, IARC |
| 10:40am | Coffee break |
| 11:10am | The experience of the IARC Monographs. V. Cogliano, IARC |
| 11:30am | Session 1 - Discussion |
| Session II: | Cumulative evidence on genetic determinants of cancer and carcinogens (Chair: M. Khoury, CDC) |
| 11:50am | CDC: Introduction and overview M. Khoury |
| 12:05pm | Methods of HuGE reporting and systematic reviews of gene-disease association J. Little, U. Ottawa |
| 12:20pm | Evaluating cumulative evidence in genetic associations in cancer PJ. Ioannidis, U. Ioannina |
| 12:35pm | Lunch break |
| 1:35pm | Contribution of GWA to the identification of cancer genetic variants. D. Hunter, Harvard |
| 2:05pm | Functional genomics: how to strengthen assessment of causality by combining genetic and epidemiologic data? S. Tavtigian |
| 2:35pm | Session 2 – Discussion |
| Session III: | Evaluation of cumulative evidence on gene-environment interactions (Chair: P. Vineis, Imperial College) |
| 2:50pm | Tobacco-related lung carcinogenesis as a model. S. Hecht, U. Minnesota |
| 3:20pm | Coffee break |
| 3:50pm | Which gene-environment interactions have been identified in cancer etiology? N. Rothman, NCI |
| 4:20pm | Methods for systematic reviews focusing on gene-environment interaction J. Higgins, U. Cambridge |
| 4:50pm | Criteria for evaluation of gene-environment interactions in cancer research. P. Vineis, Imperial College |
| 5:10pm | Adjourn |
| May 19, 2009 | |
|---|---|
| Session III (cont'd): | Evaluation of cumulative evidence on gene-environment interactions (Chair: P. Vineis, Imperial College) |
| 9:00am | Methods for studying gene-environment interactions in candidate pathway and genome-wide association studies, with application to ionizing radiation and DNA repair in breast cancer. D. Thomas, USC |
| 9:30am | Statistical issues in the assessment of the evidence of gene-environment interactions. S. Wacholder, NCI |
| 10:00am | Session 3 – Discussion |
| 10:30am | Coffee break |
| Session IV: 11:00am |
Implications beyond cancer and beyond etiological research (Chair: C. Ambrosone, Roswell Park) |
| 11:30am | Contribution of Mendelian randomization to the identification of gene-environment interactions G. Davey-Smith, U. Bristol |
| 12:00pm | Gene-environment interaction in cancer outcome research C. Ambrosone, Roswell Park |
| 12:30pm | Lunch break |
| 1:30pm | Session 4 – Discussion |
| Session V: 2:00pm |
Implications for current evaluation programs (Chairs: J. Ioannidis, U. Ioannina; V. Cogliano) Panel discussion: J. Little, J. Higgins, H. Campbell, D. Seminara |
| 3:00pm | Coffee break |
| Session VI: 3:30pm |
Recommendations for future research (Chair: D. Winn, NCI) Panel discussion: N. Rothman, C. Ambrosone, D. Hunter, P. McKeigue, A. Poland |
| Session VII: 4:30pm |
Discussion on position paper (Chairs: M. Khoury, P. Boffetta) |
| 5:00pm | Adjourn |
| May 20, 2009 | |
|---|---|
| Special Session: 9:00am |
Personal genomics profiling companies : Current practice and implications for healthcare (Chairs: P. Brennan; G. Davey-Smith) |
| 9:30am | Special session – Discussion |
| 10:15am | Recommendations from the CDC NIH workshop on personal genomics (M. Khoury) |
| 10:30am | Coffee break |
| Special session: 11:00am |
Finalization of position paper (Chair: P. Boffetta) |
| 12:00pm | Closing |
Contact Us:
- CDC-INFO Contact Center
Phone: 800-232-4636 (800-CDC-INFO)
Hearing Impaired: 888-232-6348 - cdcinfo@cdc.gov
- Additional information for Public Health Genomics is available on our contact page.
