by June E. Eichner,1 S. Terence Dunn2 Ghazala Perveen1 David M. Thompson1
Kenneth E. Stewart1 and Berrit C. Stoehla1
Tables
|
TABLE 1: Relative frequencies of the
most common alleles for the gene locus coding for apolipoprotein ε.
| |
|
|
*ε2 |
*ε3 |
*ε4 |
| Africans (Nigerians) (9) |
Unknown |
176 |
0.028 |
0.662 |
0.310 |
| African Americans (10) |
Population based
(Alabama, ILLinois, Minnesota, California) |
1,612
men & women |
0.131 |
0.668 |
0.201 |
| American Indians (11) |
Community based
(Arizona, Oklahoma, South Dakota, North Dakota) |
1,838
men |
0.017 |
0.850 |
0.133 |
2703
women |
0.016 |
0.858 |
0.126 |
| Caucasians |
|
|
|
|
|
Framingham, Massachussetts (12)
|
Community based
(Massachusetts) |
1,123
men |
0.083 |
0.785 |
0.131 |
1,135
women |
0.077 |
0.789 |
0.133 |
Munster, West Germany (13)
|
Factory workers |
1,557
men & women |
0.082 |
0.782 |
0.136 |
Finland (14)
|
Randomly selected youths
(5 areas) |
1,577 |
0.039 |
0.767 |
0.194 |
France (15)
|
Randomly selected from regional populations |
504 |
0.081 |
0.802 |
0.117 |
Italy (16)
|
Randomly selected residents of Trieste |
260 |
0.073 |
0.827 |
0.100 |
| Chinese (17) |
Workers from Taiyuan |
141
men |
0.074 |
0.844 |
0.082 |
| Japanese (18) |
General population |
576 |
0.037 |
0.846 |
0.117 |
| Mexican Americans (6) |
Community based
(Texas) |
963
men & women |
0.039 |
0.859 |
0.102 |
TABLE 2: Frequencies of
apolipoprotein E phenotypes in the 11 populations referred to in Table 1.
| |
|
|
E2E2 |
E3E2 |
E3E3 |
E4E2 |
E4E3 |
E4E4 |
Variant |
| Africans (Nigerians) (9) |
Unknown |
176 |
0*(0)† |
5* (3)† |
81* (46)† |
5* (3)† |
66* (37)† |
19* (11)† |
|
| African Americans (10) |
Population based
(Alabama, ILLinois, Minnesota, California) |
696
men |
14* (2)* |
124*
(18)* |
302* (43)* |
40* (6)* |
196* (28)* |
20* (3)* |
|
| 916 women |
12* (1)* |
161*
(18)* |
413* (45) |
46* (5)* |
242* (26)* |
42* (5)* |
|
| American Indians (11) |
Community based
(Arizona, Oklahoma, South Dakota, North Dakota) |
1,838 men |
0† (0)* |
54† (3)* |
1,316† (71.6)* |
9† (0.5)* |
438†
(23.9)* |
21† (1.2)* |
|
| 2703 women |
3† (0.1)* |
69†
(2.6)* |
1,978† (73.2)* |
13† (0.5)* |
613†
(22.7)* |
27† (1)* |
|
| Caucasians |
|
|
|
|
|
|
|
|
|
Framingham, Massachussetts (12)
|
Community based
(Massachusetts) |
1,123 men |
10* (0.9)* |
145* (12.9)* |
707 (62.9)* |
22* (1.9)* |
205* (18.3)* |
34* (3)* |
|
| 1,135 women |
4* (0.3)* |
151* (13.3)* |
711* (62.6)* |
16* (1.4)* |
219* (19.3)* |
34* (3)* |
|
Munster, West Germany (13)
|
Factory workers |
1,557
men & women |
14† (0.9)* |
183† (11.7)* |
969† (62.2)* |
46† (2.9)* |
310†
(19.9)* |
35† (2.2)* |
|
Finland (14)
|
Randomly selected youths
(5 areas) |
1,577 |
5* (0.3)* |
85*
(5.4)* |
926* (58.7)* |
28* (1.8)* |
483* (30.6)* |
50* (3.2)* |
|
France (15)
|
Randomly selected from regional populations |
504 |
4* (0.8)† |
66* (13.09)† |
324*
(64.28)† |
8* (1.6)† |
94* (18.65) |
8* (1.58)† |
|
Italy (16)
|
Randomly selected residents of Trieste |
260 |
1‡
(0.4)‡ |
31‡ (12)‡ |
178‡ (68.4)‡ |
43‡
(16.5)‡ |
4‡ (1.5)‡ |
3‡ (1.2)‡ |
|
| Chinese (17) |
Workers from Taiyuan |
141
men |
2* (1.4)* |
17* (12.1)* |
100* (70.9)* |
0* (0)* |
21*
(14.9)* |
1* (0.7)* |
|
| Japanese (18) |
General population |
576 |
2* (0.3)* |
35* (6.1)* |
414* (71.9)* |
4* (0.7)* |
111* (19.3)* |
10* (1.7)* |
|
| Mexican Americans (6) |
Community based
(Texas) |
964
men & women |
2*
(0.21)† |
65* (6.74)† |
711* (73.8)† |
7* (0.73)† |
167* (17.32) |
11* (1.1)† |
1* (0.1)† |
* Frequencies and/or percentages given in the original article.
† Frequencies or percentages calculated from the percentages or frequencies given in the original article.
‡ Frequencies and percentages calculated from allele frequencies given in the original article.
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