Genomic Translation

A Short Course: Public Health Assessment of Genetic Tests for Screening and Prevention

September 27-28, 2004
Hyatt Regency Hotel ~ Atlanta, Ga

 

Course Summary

The CDC’s Office of Public Health Genomics and the Foundation for Blood Research co-organized a short course to inform participants about systematic approaches for evidence-based assessment of genetic tests.  The content was developed to be useful to public health and health care professionals, policy makers, and others who are involved in the development, evaluation, utilization, regulation, and reimbursement of genetic tests for screening and prevention.  Speakers addressed issues related to pre- and post-market evaluation of genetic tests, and included case studies and lessons learned from the CDC-sponsored ACCE Project and other review processes.The more than 60 professionals from the United States, Canada, the United Kingdom and the Netherlands who attended the short course were from state and Federal public health agencies, health care practice, health care provider organizations, industry, voluntary health organizations and advocacy groups, academic centers, and health technology assessment centers.

Course Agenda

Monday, September 27
8:30 - 8:45 am	Welcome and Aims of the Short Course	Muin Khoury Print[PDF 360 KB]| PPT[10.4 MB]
8:45 - 9:15 am	Issues Surrounding Genetic Testing	Linda Bradley Print[PDF 1.1 MB]| PPT[8.6 MB]
9:15 – 9:45 am	Epidemiologic Foundation for the Assessment of Genetic Tests	Julian Little Print[PDF 135 KB]| PPT[297 KB]
9:45 – 10:15 am	The ACCE Model Process	James Haddow Print[PDF 3.7 MB]| PPT[339 KB]
10:15 – 10:30 am	Break
Disorder and Setting
10:30–11:00 am	Disorder/Setting Workshop: Break-out groups	(Group designated by the color dot on your name tag)
11:00-11:15 am	Disorder/Setting: Discussion and Questions	Glenn E. Palomaki
Analytic Validity
11:15 - 12:00	Analytic Validity: HFE , CFTR & Factor V Leiden Testing	Glenn E. Palomaki Print[PDF 6 MB]| PPT[315 KB]
12:00 - 1:15 pm	Lunch
Clinical Validity
1:15 - 1:45 pm	Cystic Fibrosis Carrier Testing	Sue Richards Print[PDF 258 KB]| PPT[234 KB]
1:45 - 2:15 pm	BRCA 1/2 Mutations and Breast Cancer: An Integrated Approach Using Four Epidemiologic Parameters	Monica McClain Print[PDF 1.2 MB]| PPT[2 MB]
2:15 - 2:45 pm	A Breast/Ovarian Cancer Dataset	Glenn E. Palomaki Print[PDF 1.2 MB]| PPT[1.4 MB]
2:45 - 3:00 pm	Colorectal Cancer Testing	Sue Richards
3:00 - 3:15 pm	Questions
3:15 - 3:30	Break
Clinical Utility
3:30 - 4:00 pm	Clinical Utility Overview	Glenn E. Palomaki Print[PDF 93 KB]| PPT[198 KB]
4:00 - 4:30 pm	Evaluating the Health Outcomes from Newborn Screening for Cystic Fibrosis	Scott Grosse Print[PDF 502 KB]| PPT[482 KB]
4:30 - 5:00 pm	Family History as a Screening Tool for Public Health and Preventive Medicine	Paula Yoon Print[PDF 618 KB]| PPT[6.1 MB]