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Genomics and Population Health 2005

Table of Content

I. Public Health Research

Chapter 1
The Role of Human Genomics in Acute Public Health Investigations:
Current Practice and Future Strategies

Incorporating Human Genomics into Acute Public Health Investigations • Examples of Investigations • APHI Workshop Held in May 2004 • Conclusions from APHI Workshop • Current Public Health Research Priorities

Chapter 2
CDC’s Family History Public Health Initiative: 2005 Update
Family History for the Public • U.S. Surgeon General’s Family History Initiative • MMWR • Family Healthware™ • Evaluation Study • Public Health Research

Chapter 3
Genomics and Vaccine Safety: Research for Future Practice
Need for Vaccine Safety Research • Current Vaccine Safety Research at CDC • Integrating Genomics into Vaccine Safety Studies • The Future of Genomics and Vaccine Safety

Chapter 4
Direct-to-Consumer Marketing Campaign: Genetic Testing for Susceptibility to Breast and Ovarian Cancer
The Direct-to-Consumer Marketing Campaign • Public Health Significance • The Complexity of BRCA1 and BRCA2 Testing • BRCA1 and BRCA2 Tests Are Not Appropriate for Most Women • Direct-to-Consumer Advertising • Public Health Response • Survey Development • Consumer Survey Results • Provider Survey Results • Conclusions


II. Genetic Testing

Chapter 5
ACCE Reviews of Genetic Tests: BRCA1, BRCA2, and CFTR
Introduction to ACCE • The ACCE Review Process • Family History and BRCA1 and BRCA2 Mutation Testing to Identify Women at Risk for Inherited Breast/Ovarian Cancer • Preconception and Prenatal Screening for Cystic Fibrosis via CFTR Carrier Testing • Lessons Learned

Chapter 6
Evaluation of Genomic Applications in Practice and Prevention: Implementation and Evaluation of a Model Approach
What is the EGAPP™ Project? • The ACCE Project • Why is Evaluation of Emerging Genomic Applications a Public Health Issue? • EGAPP™ Working Group • Stakeholders • Other EGAPP™ Activities • Expert Meeting on Evidence-Based Review of Genomic Applications • Why Might EGAPP™ Project Activities Interest State and Local Public Health Professionals? • How Will Success Be Measured?

Chapter 7
Newborn Screening for Cystic Fibrosis: A Public Health Response
What is Cystic Fibrosis? • Why Test Newborns for Cystic Fibrosis? • Public Health Response • Weighing the Costs and Benefits for Universal Newborn Screening for CF • Adding CF Screening to Existing Newborn Screening Programs • Challenges in Implementing CF Screening • Laboratory Implementation Issues • Follow-up and Communication Issues • Conclusion

Chapter 8
Enhancing Genetic Testing for Rare Diseases: Improving Availability, Access, and Quality
Genetic Testing for Rare Diseases • What is a Rare Disease? • Public Health Implications of Improving the Translation of Rare Disease Genetic Testing • Promoting Quality Laboratory Testing for Rare Diseases: Keys to Ensuring Quality Genetic Testing • Public Health Actions: Improving the Translation of Tests for Rare Diseases from Research to Clinical Practice • Public Health Actions: Ensuring Access and Quality of Rare Disease Testing


III. Public Health Practice

Chapter 9
Centers for Genomics and Public Health: An Update
University of Michigan Center for Genomics and Public Health • University of North Carolina Center for Genomics and Public Health • University of Washington Center for Genomics and Public Health • Centers’ Collaborative Activities • Summary of the Centers’ Activities

Chapter 10
Developing State Capacity for Integrating Genomics into Chronic Disease Prevention Programs: An Update
Michigan Department of Community Health • Minnesota Department of Health Chronic Disease Genomics Project • Oregon State Genetics Program • Utah Department of Health: Chronic Disease Genomics Program • Summary of the States’ Activities


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    800-CDC-INFO (800-232-4636)
  • Additional information for Public Health Genomics is available on our contact page. The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Road Atlanta, GA 30329-4027, USA
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