Treatment and Outcomes for Fungal Keratitis

Fungal keratitis must be treated with prescription antifungal medicine for several months. Natamycin is a topical ophthalmic antifungal medication that works well on superficial corneal infections, particularly those caused by filamentous fungi such as Aspergillus and Fusarium species. However, corneal infections that are deeper and more severe usually require treatment with systemic antifungal medication such as amphotericin B, fluconazole, or voriconazole. Patients who do not get better after topical and oral antifungal medications may require surgery, including corneal transplantation.