What is foodborne illness (disease, infection)?
Foodborne illness (sometimes called "foodborne disease," "foodborne infection," or "food poisoning) is a common, costly—yet preventable—public health problem. Each year, 1 in 6 Americans gets sick by consuming contaminated foods or beverages. Many different disease-causing microbes, or pathogens, can contaminate foods, so there are many different foodborne infections. In addition, poisonous chemicals, or other harmful substances can cause foodborne diseases if they are present in food.
- More than 250 different foodborne diseases have been described. Most of these diseases are infections, caused by a variety of bacteria, viruses, and parasites that can be foodborne.
- Other diseases are poisonings, caused by harmful toxins or chemicals that have contaminated the food, for example, poisonous mushrooms.
- These different diseases have many different symptoms, so there is no one "syndrome" that is foodborne illness. However, the microbe or toxin enters the body through the gastrointestinal tract, and often causes the first symptoms there, so nausea, vomiting, abdominal cramps and diarrhea are common symptoms in many foodborne diseases.
Many microbes can spread in more than one way, so we cannot always know that a disease is foodborne. The distinction matters, because public health authorities need to know how a particular disease is spreading to take the appropriate steps to stop it.
- For example, Escherichia coliO157:H7 infections can spread through contaminated food, contaminated drinking water, contaminated swimming water, and from toddler to toddler at a day care center. Depending on which means of spread caused a case, the measures to stop other cases from occurring could range from removing contaminated food from stores, chlorinating a swimming pool, or closing a child day care center.
Learn more about foodborne illness.
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What are the most common foodborne diseases?
According to CDC's 2011 Estimates for Foodborne Illness eight known pathogens account for the vast majority of illnesses, hospitalizations, and deaths. Tables 1–3 list the top five pathogens causing illness, hospitalization, and death.
Pathogens causing the most illnesses, hospitalizations, and deaths each year
Eight known pathogens account for the vast majority of illnesses, hospitalizations, and deaths. Tables 1–3 list the top five pathogens causing illness, hospitalization, and death.
Table 1. Top five pathogens contributing to domestically acquired foodborne illnesses
||Estimated number of illnesses
||90% Credible Interval
Table 2. Top five pathogens contributing to domestically acquired foodborne illnesses resulting in hospitalization
||Estimated number of hospitalizations
||90% Credible Interval
|E.coli (STEC) O157
Table 3. Top five pathogens contributing to domestically acquired foodborne illnesses resulting in death
See tables of illnesses, hospitalizations, and deaths caused by all 31 pathogens
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Tracking trends in foodborne illness since 1996, the Foodborne Diseases Active Surveillance Network (FoodNet) has conducted active, population-based surveillance for 9 laboratory-confirmed infections commonly transmitted through food including Campylobacter, Cryptosporidium, Cyclospora, Listeria, Salmonella, Shiga toxin-producing Escherichia coli O157 and non-O157, Shigella, Vibrio, and Yersinia. FoodNet is a collaborative program among CDC, 10 state health departments, the U.S. Department of Agriculture's Food Safety and Inspection Service (USDA-FSIS), and the Food and Drug Administration (FDA). FoodNet personnel located at state health departments regularly contact the clinical laboratories in Connecticut, Georgia, Maryland, Minnesota, New Mexico, Oregon, Tennessee, and selected counties in California, Colorado, and New York to find out about all infections diagnosed in residents of these areas.
The most common foodborne infections from the 2011 Estimates of Foodborne Illness and from those tracked by FoodNet include those caused by:
Campylobacter is a bacterial pathogen that causes fever, diarrhea, and abdominal cramps. It is the most commonly identified bacterial cause of diarrheal illness in the world. These bacteria live in the intestines of healthy birds, and most raw poultry meat has Campylobacter on it. Eating undercooked chicken, or other food that has been contaminated with juices dripping from raw chicken is the most frequent source of this infection (tracked by FoodNet).
Clostridium perfringens (C. perfringens) is a spore-forming gram-positive bacterium that is found in many environmental sources as well as in the intestines of humans and animals. C. perfringens is commonly found on raw meat and poultry. It can survive in conditions with very little or no oxygen. C. perfringens produces a toxin that causes illness.
Norovirus (previously called Norwalk-like virus) is an extremely common cause of foodborne illness, though it is rarely diagnosed, because the laboratory test is not widely available. It causes an acute gastrointestinal illness, usually with more vomiting than diarrhea, that generally resolves within three days. Unlike many foodborne pathogens that have animal reservoirs, norovirus spreads primarily from one infected person to another, often through contaminated food, water, or environmental surfaces. Infected kitchen workers can contaminate a salad or sandwich as they prepare it, if they have the virus on their hands. Sewage discharge into coastal growing waters have contaminated oysters before they are harvested.
Salmonella is a bacterium that is widespread in the intestines of birds, reptiles and mammals. It can spread to humans via a variety of different foods of animal origin. The illness it causes, salmonellosis, typically includes fever, diarrhea and abdominal cramps. In persons with poor underlying health or weakened immune systems, it can invade the bloodstream and cause life-threatening infections (tracked by FoodNet). For more information on Salmonella, please visit:
The Shigella germ is actually a family of bacteria that can cause diarrhea in humans. They are microscopic living creatures that pass from person to person. Shigella were discovered over 100 years ago by a Japanese scientist named Shiga, for whom they are named. There are several different kinds of Shigella bacteria: Shigella sonnei, also known as "Group D" Shigella, accounts for over two-thirds of shigellosis in the United States. Shigella flexneri, or "group B" Shigella, accounts for almost all the rest. Other types of Shigella are rare in this country, though they continue to be important causes of disease in the developing world. One type found in the developing world, Shigella dysenteriae type 1, can cause deadly epidemics (tracked by FoodNet).
Some common diseases are occasionally foodborne, even though they are usually transmitted by other routes. These include infections caused by Shigella, hepatitis A, and the parasites Giardia lamblia and Cryptosporidia. Even strep throats have been transmitted occasionally through food.
In addition to disease caused by direct infection, some foodborne diseases are caused by the presence of a toxin in the food that was produced by a microbe in the food.
- For example, the bacterium Staphylococcus aureus can grow in some foods and produce a toxin that causes intense vomiting.
- The rare but deadly disease botulism occurs when the bacterium Clostridium botulinum grows and produces a powerful paralytic toxin in foods. These toxins can produce illness even if the microbes that produced them are no longer there.
- Other toxins and poisonous chemicals can cause foodborne illness. People can become ill if a pesticide is inadvertently added to a food, or if naturally poisonous substances are used to prepare a meal. Every year, people become ill after mistaking poisonous mushrooms for safe species, or after eating poisonous reef fishes.
Learn more about the most common foodborne diseases.
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How many cases of foodborne disease are there in the United States?
CDC estimates that each year roughly 1 in 6 Americans (or 48 million people) gets sick, 128,000 are hospitalized, and 3,000 die of foodborne diseases. The 2011 estimates provide the most accurate picture yet of which foodborne bacteria, viruses, microbes ("pathogens") are causing the most illnesses in the United States . According to the 2011 estimates, the most common foodborne illnesses are caused by norovirus and by the bacteria Salmonella, Clostridium perfringens, and Campylobacter.
Learn more about current estimates of foodborne diseases.
Are the types of foodborne diseases changing?
The spectrum of foodborne diseases is constantly changing. A century ago, typhoid fever, tuberculosis and cholera were common foodborne diseases. Improvements in food safety, such as pasteurization of milk, safe canning, and disinfection of water supplies have conquered those diseases. Today other foodborne infections have taken their place, including some that have only recently been discovered.
- In 1996, the parasite Cyclospora suddenly appeared as a cause of diarrheal illness related to Guatemalan raspberries. These berries had just started to be grown commercially in Guatemala, and somehow became contaminated in the field there with this unusual parasite.
- In 1998, a new strain of the bacterium Vibrio parahemolyticus contaminated oyster beds in Galveston Bay and caused an epidemic of diarrheal illness in persons eating the oysters raw. The affected oyster beds were near the shipping lanes, which suggested that the bacterium arrived in the ballast water of freighters and tankers coming into the harbor from distant ports.
- Newly recognized microbes emerge as public health problems for several reasons: microbes can easily spread around the world, new microbes can evolve, the environment and ecology are changing, food production practices and consumption habits change, and because better laboratory tests can now identify microbes that were previously unrecognized.
In the last 15 years, several important diseases of unknown cause have turned out to be complications of foodborne infections.
- For example, we now know that the Guillain-Barre syndrome can be caused by Campylobacter infection.
- The most common cause of acute kidney failure in children, hemolytic uremic syndrome, is caused by infection with E. coli O157:H7 and related bacteria. In the future, other diseases whose origins are currently unknown may turn out be related to foodborne infections.
Learn more about trends in foodborne illness.
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What are some critical unsolved problems in foodborne disease?
As new foodborne problems emerge, several questions need to be answered before the problem can be successfully controlled. It takes careful scientific observation and research to answer these questions. Some pressing unanswered questions include:
- How do the foodborne pathogens spread among the animals themselves, and how can this be prevented? This includes E. coli O157:H7 among cattle, Salmonella Enteritis among egg-laying hens, and Campylobacter in broiler chickens. If we could prevent the animals from becoming infected in the first place, we would not have as much illness in the humans who eat them.
- What is the microbial cause of outbreaks in which no pathogen can be identified by current methods? This is true for over half of the reported foodborne outbreaks. Will wider application of existing experimental diagnostic methods help, or are these outbreaks caused by pathogens we simply do not yet know how to identify?
- What would be the impact of basic food safety education of restaurant workers on the risk of foodborne disease among restaurant patrons?
- How can the food and water that animals consume be made safer?
- How can we dispose of animal manure usefully, without threatening the food supply and the environment?
- How can basic food safety principles be most effectively taught to school children?
- How can we be sure food safety standards in other countries are as good as those in the United States? As we import more of our fresh foods from other countries, we need to be confident that they are produced with the same level of safety as food in the United States.
- What control strategies in the slaughter plant will reduce the contamination of poultry meat with Campylobacter?
- How can irradiation pasteurization of certain high risk foods, such as ground beef, be used most effectively?
- How do raspberries in Central America get contaminated with Cyclospora in the first place? Does this parasite have an animal reservoir?
- How can alfalfa sprouts and other raw sprouts be produced safely? Sprouts are unique among foods in that the conditions for sprouting are also perfect for bacterial growth, and they are not cooked after that.
Learn more about the need for improvements and innovations in future estimates of foodborne illness.
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Outbreaks and surveillance (tracking)
How do public health departments track foodborne diseases?
Routine monitoring of important diseases by public health departments is called disease surveillance. Each state decides which diseases are to be under surveillance in that state.
- In most states, diagnosed cases of salmonellosis, E. coli O157:H7 and other serious infections are routinely reported to the health department.
- The county reports them to the state health department, which reports them to CDC. Tens of thousands of cases of these "notifiable diseases" are reported every year.
- However, most foodborne infections go undiagnosed and unreported, either because the ill person does not see a doctor, or the doctor does not make a specific diagnosis. Also, infections with some microbes, such as norovirus, are not reportable in the first place, unless they are associated with a recognized outbreak.
To get more information about infections that might be diagnosed but not reported, CDC developed a special surveillance system called FoodNet.
- FoodNet is a collaborative program among CDC, 10 state health departments, the U.S. Department of Agriculture's Food Safety and Inspection Service (USDA-FSIS), and the Food and Drug Administration (FDA).
- It provides the best available information about specific foodborne infections in the United States, and summarizes them in an annual report.
- FoodNet has conducted active, population-based surveillance for laboratory-confirmed infections caused by Campylobacter, Listeria, Salmonella, STEC O157, Shigella, Vibrio, and Yersinia since 1996; Cryptosporidium and Cyclospora since 1997; and STEC non-O157 since 2000.
- The surveillance area includes 15% of the United States population (46 million persons).
In addition to tracking the number of reported cases of individual infections, states also collect information about foodborne outbreaks, and report a summary of that information to CDC. More than 1,000 foodborne outbreaks investigated by local and state health departments are reported each year. This includes information about many diseases that are not notifiable and thus are not under individual surveillance, so it provides some useful general information about foodborne diseases.
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What is a foodborne disease outbreak and why do they occur?
An outbreak of foodborne illness occurs when a group of people consume the same contaminated food and two or more of them come down with the same illness.
- It may be a group that ate a meal together somewhere, or it may be a group of people who do not know each other at all, but who all happened to buy and eat the same contaminated item from a grocery store or restaurant. For an outbreak to occur, something must have happened to contaminate a batch of food that was eaten by a group of people.
- Often, a combination of events contributes to the outbreak. A contaminated food may be left out a room temperature for many hours, allowing the bacteria to multiply to high numbers, and then be insufficiently cooked to kill the bacteria.
Many outbreaks are local in nature. They are recognized when a group of people realize that they all became ill after a common meal, and someone calls the local health department. This classic local outbreak might follow a catered meal at a reception, a pot-luck supper, or eating a meal at an understaffed restaurant on a particularly busy day. However, outbreaks are increasingly being recognized that are more widespread, that affect persons in many different places, and that are spread out over several weeks.
- For example, a recent outbreak of salmonellosis was traced to persons eating a breakfast cereal produced at a factory in Minnesota, and marketed under several different brand names in many different states. No one county or state had very many cases and the cases did not know each other. The outbreak was recognized because it was caused by an unusual strain of Salmonella, and because state public health laboratories that type Salmonella strains noticed a sudden increase in this one rare strain.
- In another recent outbreak, a particular peanut snack food caused the same illness in Israel, Europe, and North America. Again, this was recognized as an increase in infections caused by a rare strain of Salmonella.
The vast majority of reported cases of foodborne illness are not part of recognized outbreaks, but occurs as individual or "sporadic" cases. It may be that many of these cases are actually part of unrecognized widespread or diffuse outbreaks. Detecting and investigating such widespread outbreaks is a major challenge to our public health system. This is the reason that new and more sophisticated laboratory methods are being used at CDC and in state public health department laboratories.
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Why do public health officials investigate outbreaks?
A foodborne outbreak is an indication that something needs to be improved in our food safety system. Public health scientists investigate outbreaks to control them, and also to learn how similar outbreaks can be prevented in the future. Just as when a fire breaks out in a large building or when an airliner crashes, two activities are critical when an outbreak occurs.
- First, emergency action is needed to keep the immediate danger from spreading, and second, a detailed objective scientific investigation is needed to learn what went wrong, so that future similar events can be prevented.
- Much of what we know about foodborne disease and its prevention comes from detailed investigation of outbreaks. This is often how a new pathogen is identified, and this is how the critical information linking a pathogen to a specific food and animal reservoir is first gathered. The full investigation can require a team with multiple talents, including the epidemiologist, microbiologist, food sanitarian, food scientist, veterinarian, and factory process engineer.
How are outbreaks of foodborne disease detected?
The initial clue that an outbreak is occurring can come in various ways.
- It may be when a person realizes that several other people who were all together at an event have become ill and he or she calls the local health department.
- It may be when a physician realizes she has seen more than the usual number of patients with the same illness.
- It may be when a county health department gets an unusually large number of reports of illness.
- The hardest outbreaks to detect are those that are spread over a large geographic area, with only a few cases in each state. These outbreaks can be detected by combining surveillance reports at the regional or national level and looking for increases in infections of a specific type. This is why state public health laboratories determine the serotype of Salmonella bacteria isolated from people.
- New "DNA fingerprinting" technologies can make detecting outbreaks easier too. For example, the new molecular subtyping network, PulseNet, allows state laboratories and CDC to compare strains of E. coli O157:H7 and an increasing number of other pathogens from all across the United States to detect widespread outbreaks.
After an apparent cluster of cases is detected, it is important to determine whether these cases represent a real increase above the expected number of cases and whether they really might be related.
- Sometimes a cluster of reported cases is caused by something other than an actual outbreak of illness. For example, if the person responsible for reporting has just returned from a vacation and is clearing up a backlog of cases by reporting them all at once, the sudden surge of reports is just a false cluster.
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How is a foodborne disease outbreak investigated?
- Once an outbreak is strongly suspected, an investigation begins.
- A search is made for more cases among persons who may have been exposed. The symptoms and time of onset, and location of possible cases is determined, and a "case definition" is developed that describes these typical cases.
- The outbreak is systematically described by time, place, and person. A graph is drawn of the number of people who fell ill on each successive day to show pictorially when it occurred. A map of where the ill people live, work, or eat may be helpful to show where it occurred. Calculating the distribution of cases by age and sex shows who is affected. If the causative microbe is not known, samples of stool or blood are collected from ill people and sent to the public health laboratory to make the diagnosis.
- To identify the food or other source of the outbreak, the investigators first interview a few persons with the most typical cases about exposures they may have had in the few days before they got sick. In this way, certain potential exposures may be excluded while others that are mentioned repeatedly emerge as possibilities.
- Combined with other information, such as the likely sources for the specific microbe involved, these hypotheses are then tested in a formal epidemiologic investigation.
- The investigators conduct systematic interviews about a list of possible exposures with the ill persons, and with a comparable group people who are not ill. By comparing how often an exposure is reported by ill people and by well people, investigators can measure the association of the exposure with illness. Using probability statistics, similar to those used to describe coin flips, the probability of no association is directly calculated.
For example, imagine that an outbreak has occurred after a catered event. Initial investigation suggested that Hollandaise sauce was eaten by at least some of the attendees, so it is on the list of possible hypotheses.
- Now, we interview 20 persons who attended the affair, 10 of whom became ill and 10 who remained well. Each ill or well person is interviewed about whether or not they ate the Hollandaise sauce, as well as various other food items.
- If half the people ate the sauce, but the sauce was not associated with the illness, then we would expect each person to have a 50/50 chance of reporting that they ate it, regardless of whether they were ill or not.
- Suppose, however, that we find that all 10 ill people but none of the well persons reported eating Hollandaise sauce at the event? This would be very unlikely to occur by chance alone if eating the Hollandaise sauce were not somehow related to the risk of illness. In fact, it would be about as unlikely as getting heads ten times in a row by flipping a coin (That is 50% multiplied by itself 10 times over, or a chance of just under 1 in 1000).
- So the epidemiologist concludes that eating the Hollandaise sauce was very likely to be associated with the risk of illness. Note that the investigator can draw this conclusion even though there is no Hollandaise sauce left to test in a laboratory.
- The association is even stronger if she can show that those who ate second helpings of Hollandaise were even more likely to become ill, or that persons who ate leftover Hollandaise sauce that went home in doggie bags also became ill.
Once a food item is statistically implicated in this manner, further investigation into its ingredients and preparation, and microbiologic culture of leftover ingredients or the food itself (if available) may provide additional information about the nature of contamination.
- Perhaps the Hollandaise sauce was made using raw eggs. The source of the raw eggs can be determined, and it may even be possible to trace them back to the farm and show that chickens on the farm are carrying the same strain of Salmonella in their ovaries. If so, the eggs from that farm can be pasteurized to prevent them from causing other outbreaks.
- Some might think that the best investigation method would be just to culture all the leftover foods in the kitchen, and conclude that the one that is positive is the one that caused the outbreak. The trouble is that this can be misleading, because it happens after the fact. What if the Hollandaise sauce is all gone, but the spoon that was in the sauce got placed in potato salad that was not served at the function? Now, cultures of the potato salad yield a pathogen, and the unwary tester might call that the source of the outbreak, even though the potato salad had nothing to do with it. This means that laboratory testing without epidemiologic investigation can lead to the wrong conclusion.
Even without isolating microbes from food, a well-conducted epidemiologic investigation can guide immediate efforts to control the outbreak.
- A strong and consistent statistical association between illness and a particular food item that explains the distribution of the outbreak in time, place and person should be acted upon immediately to stop further illness from occurring.
An outbreak ends when the critical exposure stops:
- This may happen because all the contaminated food is eaten or recalled, because a restaurant is closed or a food processor shuts down or changes its procedures, or an infected food handler is no longer infectious or is no longer working with food.
- An investigation that clarifies the nature and mechanism of contamination can provide critical information even if the outbreak is over.
- Understanding the contamination event well enough to prevent it can guide the decision to resume usual operations, and lead to more general prevention measures that reduce the risk of similar outbreaks happening elsewhere.
What foods are most associated with foodborne illness?
- Raw foods of animal origin are the most likely to be contaminated; that is, raw meat and poultry, raw eggs, unpasteurized milk, and raw shellfish.
- Because filter-feeding shellfish strain microbes from the sea over many months, they are particularly likely to be contaminated if there are any pathogens in the seawater.
- Foods that mingle the products of many individual animals, such as bulk raw milk, pooled raw eggs, or ground beef, are particularly hazardous because a pathogen present in any one of the animals may contaminate the whole batch.
- A single hamburger may contain meat from hundreds of animals.
- A single restaurant omelet may contain eggs from hundreds of chickens.
- A glass of raw milk may contain milk from hundreds of cows.
- A broiler chicken carcass can be exposed to the drippings and juices of many thousands of other birds that went through the same cold water tank after slaughter.
- Fruits and vegetables consumed raw are a particular concern. Washing can decrease but not eliminate contamination, so the consumers can do little to protect themselves.
- Recently, a number of outbreaks have been traced to fresh fruits and vegetables that were processed under less than sanitary conditions. These outbreaks show that the quality of the water used for washing and chilling the produce after it is harvested is critical. Using water that is not clean can contaminate many boxes of produce.
- Fresh manure used to fertilize vegetables can also contaminate them. Alfalfa sprouts and other raw sprouts pose a particular challenge, as the conditions under which they are sprouted are ideal for growing microbes as well as sprouts, and because they are eaten without further cooking. That means that a few bacteria present on the seeds can grow to high numbers of pathogens on the sprouts.
- Unpasteurized fruit juice can also be contaminated if there are pathogens in or on the fruit that is used to make it.
Learn more about what you can do to prevent foodborne illness.
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How does food become contaminated?
We live in a microbial world, and there are many opportunities for food to become contaminated as it is produced and prepared.
- Many foodborne microbes are present in healthy animals (usually in their intestines) raised for food. Meat and poultry carcasses can become contaminated during slaughter by contact with small amounts of intestinal contents.
- Similarly, fresh fruits and vegetables can be contaminated if they are washed or irrigated with water that is contaminated with animal manure or human sewage.
- Some types of Salmonella can infect a hen's ovary so that the internal contents of a normal looking egg can be contaminated with Salmonella even before the shell in formed.
- Oysters and other filter feeding shellfish can concentrate Vibrio bacteria that are naturally present in sea water, or other microbes such as norovirus that are present in human sewage dumped into the sea.
Later in food processing, other foodborne microbes can be introduced from infected humans who handle the food, or by cross contamination from some other raw agricultural product.
- For example, Shigella bacteria, hepatitis A virus and norovirus can be introduced by the unwashed hands of food handlers who are themselves infected.
- In the kitchen, microbes can be transferred from one food to another food by using the same knife, cutting board, or other utensil to prepare both, without washing the surface or utensil in between.
- A food that is fully cooked can become recontaminated if it touches other raw foods or drippings from raw foods that contain pathogens.
The way that food is handled after it is contaminated can also make a difference in whether or not an outbreak occurs.
- Many bacterial microbes need to multiply to a larger number before enough are present in food to cause disease. Given warm moist conditions and an ample supply of nutrients, one bacterium that reproduces by dividing itself every half hour can produce 17 million progeny in 12 hours.
- As a result, lightly contaminated food left out overnight can be highly infectious by the next day. If the food were refrigerated promptly, the bacteria would not multiply at all.
- In general, refrigeration or freezing prevents virtually all bacteria from growing but generally preserves them in a state of suspended animation. This general rule has a few surprising exceptions.
- High salt, high sugar or high acid levels keep bacteria from growing, which is why salted meats, jam, and pickled vegetables are traditional preserved foods.
Microbes are killed by heat.
- If food is heated to an internal temperature above 160oF, or 78oC, for even a few seconds this sufficient to kill parasites, viruses or bacteria, except for the Clostridium bacteria, which produce a heat-resistant form called a spore.
- Clostridium spores are killed only at temperatures above boiling. This is why canned foods must be cooked to a high temperature under pressure as part of the canning process.
- The toxins produced by bacteria vary in their sensitivity to heat.
- The staphylococcaltoxin which causes vomiting is not inactivated even if it is boiled.
- Fortunately, the potent toxin that causes botulism is completely inactivated by boiling.
Learn more about what you can do to prevent foodborne illness.
There is only so much the consumer can do. How can food be made safer in the first place?
Making food safe in the first place is a major effort, involving the farm and fishery, the production plant or factory, and many other points from the farm to the table. Many different groups in public health, industry, regulatory agencies, and academia have roles to play in making the food supply less contaminated. Consumers can promote general food safety with their dollars, by purchasing foods that have been processed for safety.
- For example, milk pasteurization was a major advance in food safety that was developed 100 years ago. Buying pasteurized milk rather than raw unpasteurized milk still prevents an enormous number of foodborne diseases every day.
- Now juice pasteurization is a recent important step forward that prevents E. coli O157:H7 infections and many other diseases. Consumers can look for and buy pasteurized fruit juices and ciders.
- In the future, meat and other foods will be available that has been treated for safety with irradiation. These new technologies are likely to be as important a step forward as the pasteurization of milk.
Foodborne diseases are largely preventable, though there is no simple one-step prevention measure like a vaccine. Instead, measures are needed to prevent or limit contamination all the way from the farm to the table.
- A variety of good agricultural and manufacturing practices can reduce the spread of microbes among animals and prevent the contamination of foods.
- Careful review of the whole food production process can identify the principal hazards, and the control points where contamination can be prevented, limited, or eliminated.
- A formal method for evaluating the control of risk in foods exists is called the Hazard Analysis Critical Control Point, or HACCP system. This was first developed by NASA to make sure that the food eaten by astronauts was safe. HACCP safety principles are now being applied to an increasing spectrum of foods, including meat, poultry, and seafood.
For some particularly risky foods, even the most careful hygiene and sanitation are insufficient to prevent contamination, and a definitive microbe-killing step must be included in the process.
- For example, early in the century, large botulism outbreaks occurred when canned foods were cooked insufficiently to kill the botulism spores. After research was done to find out exactly how much heat was needed to kill the spores, the canning industry and the government regulators went to great lengths to be sure every can was sufficiently cooked. As a result, botulism related to commercial canned foods has disappeared in this country.
- Similarly the introduction of careful pasteurization of milk eliminated a large number of milk-borne diseases. This occurred after sanitation in dairies had already reached a high level.
- In the future, other foods can be made much safer by new pasteurizing technologies, such as in-shell pasteurization of eggs, and irradiation of ground beef. Just as with milk, these new technologies should be implemented in addition to good sanitation, not as a replacement for it.
In the end, it is up to the consumer to demand a safe food supply; up to industry to produce it; up to researchers to develop better ways of doing so; and up to government to see that it happens, to make sure it works and to identify problems still in need of solutions.
Learn more about what you can do to prevent foodborne illness.
What is CDC doing to control and prevent foodborne disease?
CDC is part of the U. S. Public Health Service, with a mission to use the best scientific information to monitor, investigate, control and prevent public health problems.
- Using the tools of epidemiology and laboratory science, CDC provides scientific assessment of public health threats.
- CDC works closely with state health departments to monitor the frequency of specific diseases and conducts national surveillance for them.
- CDC provides expert epidemiologic and microbiologic consultation to health departments and other federal agencies on a variety of public health issues, including foodborne disease, and it stations epidemiologists in state health departments to help with the surveillance and investigation of many problems.
- CDC can also send a team into the field to conduct emergency field investigations of large or unusual outbreaks, in collaboration with state public health officials.
- CDC researchers develop new methods for identifying, characterizing and fingerprinting the microbes that cause disease.
- We translate laboratory research into practical field methods that can be used by public health authorities in states and counties.
CDC is not a regulatory agency. Government regulation of food safety is carried out by the Food and Drug Administration (FDA) , the U.S. Department of Agriculture (USDA), the National Marine Fisheries Service, and other regulatory agencies. CDC maintains regular contact with the regulatory agencies.
When new public health threats appear, CDC learns what they are and how they can be controlled through rapid scientific field and laboratory investigation.
- CDC shares the results of these investigations with the states, with the regulatory federal agencies and with the industries themselves.
- Although we do not regulate the safety of food, CDC assesses the effectiveness of current prevention efforts.
- We provide independent scientific assessment of what the problems are, how they can be controlled, and of where there are gaps in our knowledge.
For more information about CDC's role in preventing and responding to foodborne disease, please see:
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Diagnosing and treating foodborne illness
What happens in the body after the microbes that produce illness are swallowed?
After the microbes are swallowed, there is a delay, called the incubation period, before the symptoms of illness begin. This delay may range from hours to days, depending on the organism, and on how many of them were swallowed.
- During the incubation period, the microbes pass through the stomach into the intestine, attach to the cells lining the intestinal walls, and begin to multiply there.
- Some types of microbes stay in the intestine, some produce a toxin that is absorbed into the bloodstream, and some can directly invade the deeper body tissues. The symptoms produced depend greatly on the type of microbe.
- Numerous organisms cause similar symptoms, especially diarrhea, abdominal cramps, and nausea. There is so much overlap that it is rarely possible to say which microbe is likely to be causing a given illness unless laboratory tests are done to identify the microbe, or unless the illness is part of a recognized outbreak.
How are foodborne diseases diagnosed?
The infection is usually diagnosed by specific laboratory tests that identify the causative organism.
- Bacteria such as Campylobacter, Salmonella, E. coli O157 are found by culturing stool samples in the laboratory and identifying the bacteria that grow on the agar or other culture medium.
- Parasites can be identified by examining stools under the microscope.
- Viruses are more difficult to identify, as they are too small to see under a light microscope and are difficult to culture. Viruses are usually identified by testing stool samples for genetic markers that indicate a specific virus is present.
Many foodborne infections are not identified by routine laboratory procedures and require specialized, experimental, and/or expensive tests that are not generally available.
- If the diagnosis is to be made, the patient has to seek medical attention, the physician must decide to order diagnostic tests, and the laboratory must use the appropriate procedures.
- Because many ill persons to not seek attention, and of those that do, many are not tested, many cases of foodborne illness go undiagnosed, and most illnesses are not laboratory-confirmed.
- For example, it is estimated that 29 Salmonella illnesses occur for every one that is laboratory-confirmed and that many hospitalizations and deaths caused by Salmonella infection are not ascertained
How are foodborne diseases treated?
There are many different kinds of foodborne diseases and they may require different treatments, depending on the symptoms they cause. Illnesses that are primarily diarrhea or vomiting can lead to dehydration if the person loses more body fluids and salts (electrolytes) than they take in.
- Replacing the lost fluids and electrolytes and keeping up with fluid intake are important.
- If diarrhea is severe, oral rehydration solution such as Ceralyte*, Pedialyte* or Oralyte*, should be drunk to replace the fluid losses and prevent dehydration. Sports drinks such as Gatorade* do not replace the losses correctly and should not be used for the treatment of diarrheal illness.
- Preparations of bismuth subsalicylate (e.g., Pepto-Bismol*) can reduce the duration and severity of simple diarrhea.
- If diarrhea and cramps occur, without bloody stools or fever, taking an antidiarrheal medication may provide symptomatic relief, but these medications should be avoided if there is high fever or blood in the stools because they may make the illness worse.
*CDC does not endorse commercial products or services.
When should I consult my doctor about a diarrheal illness?
A health care provider should be consulted for a diarrheal illness is accompanied by:
- High fever (temperature over 101.5 F, measured orally)
- Blood in the stools
- Prolonged vomiting that prevents keeping liquids down (which can lead to dehydration)
- Signs of dehydration, including a decrease in urination, a dry mouth and throat, and feeling dizzy when standing up.
- Diarrheal illness that lasts more than 3 days
Do not be surprised if your doctor does not prescribe an antibiotic.
- Many diarrheal illnesses are caused by viruses and will improve in 2 or 3 days without antibiotic therapy.
- In fact, antibiotics have no effect on viruses, and using an antibiotic to treat a viral infection could cause more harm than good.
- It is often not necessary to take an antibiotic even in the case of a mild bacterial infection. Other treatments can help the symptoms, and careful handwashing can prevent the spread of infection to other people.
- Overuse of antibiotics is the principal reason many bacteria are becoming resistant.
- Resistant bacteria are no longer killed by the antibiotic.
- This means that it is important to use antibiotics only when they are really needed.
- Partial treatment can also cause bacteria to become resistant. If an antibiotic is prescribed, it is important to take all of the medication as prescribed, and not stop early just because the symptoms seem to be improving.
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Protecting yourself from foodborne illness
What can consumers do to protect themselves from foodborne illness?
A few simple precautions can reduce the risk of foodborne diseases:
- COOK meat, poultry and eggs thoroughly.
- Using a food thermometer to measure the internal temperature of meat is a good way to be sure that it is cooked sufficiently to kill bacteria.
- Eggs should be cooked until the yolk is firm.
- SEPARATE: Don't cross-contaminate one food with another.
- Avoid cross-contaminating foods by washing hands, utensils, and cutting boards after they have been in contact with raw meat or poultry and before they touch another food.
- Put cooked meat on a clean platter, rather back on one that held the raw meat.
- CHILL: Refrigerate leftovers promptly.
- Bacteria can grow quickly at room temperature, so refrigerate leftover foods if they are not going to be eaten within 4 hours.
- Large volumes of food will cool more quickly if they are divided into several shallow containers for refrigeration.
- CLEAN: Wash produce.
- Rinse fresh fruits and vegetables in running tap water to remove visible dirt and grime.
- Remove and discard the outermost leaves of a head of lettuce or cabbage.
- Because bacteria can grow well on the cut surface of fruit or vegetable, be careful not to contaminate these foods while slicing them up on the cutting board, and avoid leaving cut produce at room temperature for many hours.
- Don't be a source of foodborne illness yourself.
- Wash your hands with soap and water before preparing food.
- Avoid preparing food for others if you yourself have a diarrheal illness.
- Changing a baby's diaper while preparing food is a bad idea that can easily spread illness.
- REPORT: Report suspected foodborne illnesses to your local health department.
- The local public health department is an important part of the food safety system.
- Often calls from concerned citizens are how outbreaks are first detected.
- If a public health official contacts you to find out more about an illness you had, your cooperation is important. In public health investigations, it can be as important to talk to healthy people as to ill people.
- Your cooperation may be needed even if you are not ill.
Learn more about what consumers can do to protect themselves from foodborne illness.
Are some people more likely to contract a foodborne illness? If so, are there special precautions they should take?
Some persons at particularly high risk should take more precautions.
- Pregnant women, the elderly, and those weakened immune systems are at higher risk for severe infections such as Listeria and should be particularly careful not to consume undercooked animal products. They should avoid soft French-style cheeses, pates, uncooked hot dogs and sliced deli meats, which have been sources of Listeria infections. Persons at high risk should also avoid alfalfa sprouts and unpasteurized juices.
- A bottle-fed infant is at higher risk for severe infections with Salmonella or other bacteria that can grow in a bottle of warm formula if it is left at room temperature for many hours. Particular care is needed to be sure the baby's bottle is cleaned and disinfected and that leftover milk formula or juice is not held in the bottle for many hours.
- Persons with liver disease are susceptible to infections with a rare but dangerous microbe called Vibrio vulnificus, found in oysters. They should avoid eating raw oysters.
Learn more about what consumers can do to protect themselves from foodborne illness.
What can consumers do when they eat in restaurants?
You can protect yourself first by choosing which restaurant to patronize.
- Restaurants are inspected by the local health department to make sure they are clean and have adequate kitchen facilities.
- Find out how restaurants did on their most recent inspections, and use that score to help guide your choice.
- In many jurisdictions, the latest inspection score is posted in the restaurant.
- Some restaurants have specifically trained their staff in principles of food safety. This is also good to know in deciding which restaurant to patronize.
You can also protect yourself from foodborne disease when ordering specific foods, just as you would at home.
- When ordering a hamburger, ask for it to be cooked to a temperature of 160ºF and send it back if it is still pink in the middle.
- Before you order something that is made with many eggs pooled together, such as scrambled eggs, omelets, or French toast, ask the waiter whether it was made with pasteurized egg, and choose something else if it was not.
Learn more about what consumers can do to protect themselves from foodborne illness in restaurants.
Where can I learn more about food safety and foodborne illnesses?
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