Chronic Hepatitis B Virus Infection

2003 Case Definition

Clinical description

Persons with chronic hepatitis B virus (HBV) infection may be asymptomatic. They may have no evidence of liver disease or may have a spectrum of disease ranging from chronic hepatitis to cirrhosis or liver cancer.

Laboratory criteria for diagnosis

• Hepatitis B surface antigen (HBsAg) positive, total anti-HBc positive (if done) and IgM anti-HBc negative, OR
• HBsAg positive two times at least 6 months apart.

Case classification

Confirmed: a case that is laboratory confirmed.

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