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Quality of Life, Mental Health, Epilepsy Co-morbidity Studies

This page provides an overview of the research CDC has supported to understand how epilepsy impacts quality of life, mental health conditions associated with epilepsy, and other co-occurring conditions.
 

The Impact of Epilepsy on Quality of Life in the Elderly

University of Alabama at Birmingham, Birmingham, AL

Purpose: to determine factors affecting quality of life in seniors with epilepsy.

Publications:

Martin R, Griffith HR, Faught E, Gilliam F, Mackey M, Vogtle L. Cognitive functioning in community dwelling older adults with intractable partial epilepsy. Epilepsia. 2005;46(2):298–303.

Martin R, Vogtle L, Gilliam F, Faught E. What are the concerns of older adults living with epilepsy? Epilepsy & Behavior. 2005;7:297–300.

Martin R, Vogtle L, Gilliam F, Faught E. Health-related quality of life in senior adults with epilepsy: what we know from randomized clinical trials and suggestions for future research. Epilepsy & Behavior. 2003;4(6):626–34.

 

California Health Interview Survey: Epilepsy and Health-related Quality of Life

UCLA Center for Health Policy Research, Los Angeles, CA

Purpose: to obtain population-based estimates of the prevalence of epilepsy and the burden of impaired quality of life among persons with epilepsy; to obtain epilepsy-related data in racial/ethnic populations; and to identify health disparities and unmet needs associated with the disorder, using a representative random-digit dialed telephone survey of 55,000 households.

Publication:

Kobau R, Zahran H, Grant D, Thurman DJ, Price PH, Zack MM. Prevalence of active epilepsy and health-related quality of life among adults with self-reported epilepsy in California: California Health Interview Survey, 2003. Epilepsia 2007; 48(10):1904–13.

 

Using Distance Technology for Treating Depression in People with Epilepsy

Emory University, Rollins School of Public Health, Atlanta, GA

Purpose: to develop a small-group, cognitive-behavioral therapy and mindfulness intervention that can be delivered to patients with epilepsy via conference call or the Internet, to help alleviate and manage symptoms of depression.

Publications:

Thompson NJ, Walker ER, Obolensky N, Winning A, Barmon C, Diiorio C, Compton MT. Distance delivery of mindfulness-based cognitive therapy for depression: project UPLIFT. Epilepsy & Behavior. 2010;19(3):247–54.

Walker ER, Obolensky N, Dini S, Thompson NJ. Formative and process evaluations of a cognitive-behavioral therapy and mindfulness intervention for people with epilepsy and depression. Epilepsy & Behavior. 2010;19(3):239–46.

 

Intervention Research on Home-Based Depression Treatment in People with Epilepsy

University of Washington, Dept. of Psychiatry & Behavioral Sciences, Seattle, WA

Purpose: to evaluate the effectiveness of the Program to Encourage Active, Rewarding Lives for Seniors (PEARLS) in adults with epilepsy who have minor or major depression or dysthymia, using a randomized controlled trial to determine the intervention's acceptability, feasibility, and outcomes in preparation for subsequent community-based dissemination.

Publications:

Ciechanowski P, Chaytor N, Miller J, Fraser R, Russo J, Unutzer J, Gilliam F. PEARLS depression treatment for individuals with epilepsy: a randomized controlled trial. Epilepsy & Behavior. 2010;19(3):225–31.

Chaytor N, Ciechanowski P, Miller JW, Fraser R, Russo J, Unutzer J, Gilliam F. Long-term outcomes from the PEARLS randomized trial for the treatment of depression in patients with epilepsy. Epilepsy & Behavior. 2011;20(3):545–549.

 

California Health Interview Survey 2005: Epilepsy, Psychological Distress, and Disease Comorbidity

University of California, Los Angeles, CA

Purpose: to assess the prevalence and severity of psychological distress among community-dwelling adults with epilepsy, using a validated mental illness instrument (Kessler 6 scale), and to assess the burden of unmet mental health need in this population, using data from the 2003 and 2005 California Health Interview Survey.

Publication:

Thompson AW, Kobau R, Park R, Grant D. Epilepsy care and mental health care for people with epilepsy: California Health Interview Survey, 2005. Prev Chronic Dis. 2012;9:110140. http://dx.doi.org/10.5888/pcd9.110140. Accessed October 9, 2014.

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