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Gestational Diabetes Care Guidelines

Insulin Management

  • Allow up to 1 week for blood glucose to improved to optimal levels in response to MNT before using insulin.
  • Consider starting insulin if more than 2 elevated blood glucoses within 1 week (fasting and/or 2 hour postprandial). Example regimen 0.4 u/kg day based on current weight.
  • Always use non-animal (minimally antigenic) insulin.
  • Many patients with isolated elevated fasting blood sugars do well with neutral protamine hagedorn (NPH) (an intermediate-acting insulin) at bedtime.
  • Patients with postprandial hyperglycemia can often be treated with a single injection of mixed insulin daily.
  • Multiple injections may be required.
  • Base insulin adjustments on home glucose monitoring results.
  • The patient should report results of daily home glucose monitoring at least 2-3 times per week during the insulin initiation period and then at least once a week when normalized.
  • Instruct patient to call physician or diabetes educator if there are 3 abnormal results between scheduled follow up visits.
  • If patient is not achieving euglycemia within 2 weeks of start of insulin therapy, then she should consult with a physician with additional expertise in managing insulin in pregnant patients.

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Page last modified: December 20, 2005

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Division of Diabetes Translation

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