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The Economics of Diabetes Mellitus:
An Annotated Bibliography

INTRODUCTION

Preface

Diabetes mellitus is a common, serious, and costly disease. An estimated 16 million Americans, or nearly 6 percent of the population, have diabetes, and the disease costs the nation nearly $100 billion annually. The prevalence has increased dramatically over the last three decades, and minority groups are disproportionately affected. Diabetes is the seventh leading cause of death and can decrease the life expectancy by 5 to 15 years. It is the leading cause of nontraumatic lower extremity amputations, renal failure, and blindness in working-age adults. Diabetes is also a major cause of premature mortality, stroke, cardiovascular disease, peripheral vascular disease, congenital malformations, perinatal mortality, and long- and short-term disability. In addition, persons with diabetic complications have a lower quality of life compared with persons without diabetes.

Interventions to reduce the burden of diabetes currently exist. Early detection and treatment of eye disease, kidney disease, and lower extremity disease can prevent or delay the development of blindness, kidney failure, and amputation. However, far too often, the level of care needed to decrease these complications is not reached. Because of the serious acute and chronic complications, persons with diabetes tend to use more health services than persons without diabetes. These resources include hospitalizations, emergency room and outpatient clinic visits, laboratory tests, medication, and self-management supplies (e.g., equipment to self-monitor blood glucose). The cost to care for diabetes exacts a tremendous burden on both the patient and payer. Several studies over the years have found that the direct health care costs (costs of medical treatment and services) related to diabetes are high.

In this era of limited resources and escalating costs, it is critical to have an understanding of the economics of diabetes in order to develop and implement sound public health and prevention policies. However, studying these economics presents several challenges, such as collecting the appropriate epidemiological and cost data, determining the diabetes attributable factors for premature morbidity and mortality, and determining methods to account for premature morality, disability, and reduced quality of life.

This bibliography includes most of the important economic studies currently available. In the past, methods used for conducting economic research were not well standardized. Although recent efforts, such as those by the Panel on Cost Effectiveness in health and Medicine, have moved forward the use of standard methodologies, much of the current literature in this bibliography and elsewhere still requires careful review of the methods. Preparation of this bibliography included contributions by experts in the field who reviewed the entries for pertinency and accuracy. We acknowledge and appreciate the contributions of

  • Thomas Songer, Ph.D., Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • William H. Herman, M.D., M.P.H., Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Christine Tobin, Diabetes Control Services, Atlanta, Georgia.

It is hoped that this bibliography will help identify major gaps in our knowledge and will assist with the development of future diabetes economic research. It also should be of assistance to public health professionals, clinicians, insurers, economists, and researchers in their efforts to create effective policy and to answer preventive questions.

 

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Page last modified: December 20, 2005

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