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The Economics of Diabetes Mellitus:
An Annotated Bibliography

TYPES OF INTERVENTION

Diabetes in Pregnancy

Pregestational Diabetes

134


TITLE: Cost-Benefit Analysis of Preconception Care for Women with Established Diabetes Mellitus. Elixhauser, A.; Wechsler, J.M.; Kitzmiller, J.L.; Marks, J.S.; Bennert Jr., H.W.; Coustan, D.R.; Gabbe, S.G.; Herman, W.H.; Kaufmann, R.C.; Ogata, E.S.; Sepe, S.J. Diabetes Care. 16(8):1146-1157. August 1993.

OBJECTIVE: To determine whether the costs of pre-conception care in women with diabetes are balanced by the savings that result from avoiding complications.

CATEGORY: Diabetes in pregnancy.

    Type of Study: Epidemiological cohort model.
    Methodology: Cost-benefit analysis.
    Perspective: Health care system.

CONCLUSION: Intensive preconception care for women with diabetes followed by prenatal care is cost saving when compared with prenatal care only.

RECOMMENDATION: None.

ABSTRACT: Literature review, consensus development, and questionnaires were used to compare the costs of preconception care plus prenatal care with the costs of prenatal care only for hypothetical groups of 1,000 women each. Preconception care was assumed to require 20 visits; the model specified that only after glycemic control was achieved and maternal health status evaluated would a couple be encouraged to conceive. For the prenatal-care-only group, care was assumed to start at gestational age of 12 weeks. The economic consequences of adverse outcomes of pregnancy included those for the mother (e.g., a stay in the intensive care unit), initial hospitalization for the newborn (costs of congenital anomalies, respiratory distress syndrome, etc.), and subsequent care for the newborn. A cost-benefit analysis (all costs in 1989 dollars) from the perspective of a third party payer was performed in which total program costs were compared with the dollar value of maternal and neonatal adverse outcomes. Net benefits and a benefit-cost ratio were computed. Net benefits equaled the sum of the costs for prenatal care only and the costs of associated adverse outcomes, minus the sum of the costs of the preconception-plus-prenatal-care program and the associated adverse outcomes. The benefit-cost ratio was calculated by dividing the difference in adverse outcome costs between the programs by the difference in program inputs. The model found that the preconception-care group incurred costs of $11,294 per enrollee and $17,519 per delivery. In contrast, cost per enrollee in the prenatal-care-only program was $12,889 and cost per delivery was $13,843 (the cost was higher in the preconception-care group because more women received medical services without going on to deliver). Rates of adverse outcomes were generally lower for the preconception-care patients. Total costs of adverse outcomes were $9,655,079 in the preconception group and $13,372,792 in the group receiving prenatal care only. Net benefit of the preconception care program was $1720 per enrollee; the benefit-cost ratio was 1.86. 6 tables, 3 appendixes, 44 references.

135


TITLE: Cost-Benefit Analysis of Preconception Care for Women with Established Diabetes Mellitus. Final Report. Elixhauser, A.; Weschler, J.M. Battelle Medical Technology and Policy Research Center, Washington, D.C., 1990.

 

 

OBJECTIVE: To analyze and compare costs and benefits of preconception care plus prenatal care versus prenatal care only in preventing adverse fetal and maternal outcomes in women with pre-existing diabetes mellitus.

CATEGORY: Diabetes in pregnancy.

    Type of Study: Epidemiological cohort model.
    Methodology: Cost-benefit analysis.
    Perspective: Health care system.

CONCLUSION: The program of preconception care plus prenatal care resulted in net savings of $1.7 million; the greatest savings were associated with reduction of adverse outcomes in mothers and infants.

RECOMMENDATION: Third party payers can expect to realize cost savings from reduced maternal and fetal complications in women with pre-existing diabetes by reimbursing for preconception care (including educational and support services provided by allied health care providers) according to standards recommended by the American Diabetes Association.

ABSTRACT: The authors constructed a model, based on literature review, review by an expert panel, and questionnaires, to compare among women with diabetes the costs and benefits associated with preconception care plus prenatal care with those for prenatal care only. The theoretical study population included 1,000 women in the preconception care program, of whom 785 became pregnant and entered prenatal care; and 1,000 women in the prenatal-care-only program, of whom 900 became pregnant. The preconception component of the program was 17 weeks long and included an initial preconception evaluation and 20 visits for medical evaluation; laboratory tests; and education, dietary, and counseling services. Women in the program were assumed to enter prenatal care six weeks after their last menstrual period. The prenatal-care-only program assumed that all women would have appropriate care and enter the prenatal program at a later stage of pregnancy (10 to 12 weeks after the last menstrual period), that 60 percent would enter the program in less than optimal control and 25 percent would require hospitalization to improve control, and that those in poor control would require more intensive medical and dietary management. Cost-benefit analysis showed that the total costs of care for women in the preconception plus prenatal care group were $11,294,100 (not including nonmedical costs); total costs for women in the prenatal-care-only group were $9,296,900. Costs associated with adverse outcomes totaled $9,655,079 for the first group and $13,372,676 for the second. Total costs for women in the second group were $1,720,397 ($1,720 per woman) higher than total costs for women receiving preconception care, resulting in a cost-benefit ratio of 1.86. 14 tables, 3 figures, 4 appendices, 80 references.

136


TITLE: Financial Implications of Implementing Standards of Care for Diabetes and Pregnancy. Elixhauser, A.; Weschler, J.; Kitzmiller, J.; Bennert, H.; Coustan, D.; Gabbe, S.; Herman, W.; Kauffmann, R.; Ogata, E.; Marks, J.; et al. Diabetes Care. 15 (Supplement 1): S22-S28. March 1992.

OBJECTIVE: To examine the financial implications of implementing standards of care for pregnancy among women with diabetes.

CATEGORY: Diabetes in pregnancy.

    Type of Study: Patient management.
    Methodology: Review of studies.
    Perspective: Health care system.

CONCLUSION: Implementing standards of care for pregnancy among women with diabetes will represent a greater use of health care resources for outpatient preconception and prenatal care but can lead to avoided costs for maternal and fetal complications of pregnancy.

RECOMMENDATION: Reimbursement should be provided by third party payers for comprehensive diabetes and pregnancy care to ensure that women with diabetes have access to the care they require to prevent adverse outcomes for themselves and their infants.

ABSTRACT: The authors examine the financial implications of implementing standards of care for pregnancy among women with diabetes. The standards of interest were developed by the American Diabetes Association and address four main areas of care: preconception care, blood glucose control, frequent visits, and specialized laboratory and diagnostic tests. As these standards did not specify the resources required for preconception and prenatal care, the authors convened a panel of physicians to outline more precise guidelines. The recommendations of the panel were examined for their economic implications. Adherence to these standards may represent additional costs to patients or third party payers for initial outpatient treatment. However, treatment-related costs of adverse outcomes of pregnancy can be enormous, particularly those due to poor maternal glucose control. Corrective surgery for infants with congenital heart malformations secondary to poor glucose control may cost up to $145,000 (1989 dollars) per survivor; lifetime care costs for infants born with severe spina bifida are estimated at $330,000, including both direct and indirect costs. In addition to avoiding costs related to poor fetal outcomes, intensive preconception and prenatal care can help to avoid expensive hospitalizations for maternal complications; hospitalization for a single episode of ketoacidosis averages $4,500. Two recent cost-benefit studies are cited that demonstrate that the savings resulting from avoided adverse pregnancy outcomes in women with diabetes outweigh the added costs of preconception care. Reimbursement of comprehensive diabetes and pregnancy care by third party payers is crucial for ensuring the care necessary to prevent adverse outcomes for these women and their infants. 1 figure, 49 references.

137


TITLE: Prevention: The Cost-Effectiveness of the California Diabetes and Pregnancy Program. Scheffler, R.M.; Feuchtbaum, L.B.; Phibbs, C.S. American Journal of Public Health. 82(2): 168-175. February 1992.

OBJECTIVE: To determine the cost-effectiveness of a California program aimed at improving pregnancy outcomes through intensive diabetes management.

CATEGORY: Tertiary intervention.

    Type of Study: Retrospective.
    Methodology: Cost-effectiveness analysis.
    Perspective: Health care system.

CONCLUSION: The program significantly reduced hospital charges and length of stay; it returned over $5 for every $1 spent.

RECOMMENDATION: None.

ABSTRACT: The California Diabetes and Pregnancy Program focuses on improving maternal and infant perinatal outcomes in pregnancies complicated by diabetes. Women in the program receive comprehensive preconception and prenatal care, including nutrition, education, and support services. Data for 102 California Diabetes and Pregnancy Program cases were collected from July 1, 1986, to July 30, 1988, from three hospitals with well-established programs, each with a level 3 neonatal intensive care unit. Data for 218 control cases were collected from five other hospitals, each with at least a level 2 neonatal intensive care unit. The demographic characteristics and health status indicators of mothers and babies at case and control hospitals were similar. Program participants and control cases of the same age, ethnicity, and diabetes classification were randomly matched, yielding a data set of 90 program cases and 90 control cases. In this data set, mean adjusted charges were $15,344 for cases, $21,699 for controls. Mean length of stay (mother and baby combined) was 15.1 days for the program cases, 18.0 days for controls. After adjustment for inflation and differences in hospital charges, for every $1 of program costs, estimated savings were $5.19. The authors' conservative assumptions suggest that actual savings are even larger than their estimates. If 2,598 babies were born to women with overt diabetes in 1990 (as estimated), yearly savings attributable to the California Diabetes and Pregnancy Program would have been $14 million to $19 million. In addition to short-term economic savings, mothers will likely have better future health status, and there should be long-term savings from fewer anomalies and other handicaps. With more normal pregnancies and healthy babies, mothers can stay in the workforce longer and return to work sooner. 6 tables, 27 references.

138


TITLE: Women with Diabetes During Pregnancy: Sociodemographics, Outcomes, and Costs of Care. York, R.; Brown, L.P. Public Health Nursing. 12(5): 290-293. October 1995.

OBJECTIVE: To provide sociodemographic, outcome, and cost data for pregnancy through the postpartum period for predominantly low-income women with diabetes who were hospitalized during pregnancy for glucose control.

CATEGORY: Diabetes in pregnancy.

    Type of Study: Patient management.
    Methodology: Cost analysis.
    Perspective: Health care system.

CONCLUSION: Women in the study were three times as likely as those in the general Pennsylvania population to deliver low-birthweight infants; mean hospital charges for these infants were $39,787.

RECOMMENDATION: Monies must be targeted to provide a broad spectrum of health care services that will meet the unique needs of low-income, childbearing women with diabetes.

ABSTRACT: The authors evaluated data for 55 women with diabetes who received care at the University of Pennsylvania Medical Center in Philadelphia between August 1988 and December 1992. Fourteen of the women had pregestational diabetes; 41, gestational diabetes. Of the 55 women, 63 percent reported annual family income of under $12,500. Data collection methods included maternal interviews, review of maternal and infant hospital charts, and postpartum telephone interviews. Mean hospital charges for antepartum initial hospitalization for glucose control, evaluation, and education were $4,665 (mean length of stay: 4.3 days). For women who required rehospitalization for glucose control, mean hospital charges were $6,371 (mean length of stay: 5.9 days). Mean charges for postpartum hospitalization were $7,793 (mean length of stay: 4.3 days). Of the 54 infants born to the study participants, 2 were stillborn and 11 were low birthweight. Mean hospital charges per infant were $12,991; for the low-birthweight infants, $39,787. Compared with Pennsylvania women as a whole, women in this study were twice as likely not to have had first-trimester care (43 percent versus 20.4 percent) and three times more likely to deliver a low-birthweight infant (20 percent versus 7.2 percent). The results provide significant evidence of the complexity of these women's health care needs and the need for monies targeted at addressing these needs. 1 table, 13 references.

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