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Central Cancer Registries

Central Cancer Registry Data Sources

A central cancer registry (CCR) collects, processes, and analyzes data on all cancer cases diagnosed in a defined geographic area. Each state in the United States has a CCR.

The central cancer registry business use case diagram shows the business process of a central cancer registry and its interaction with internal actors (those who perform the process) and external actors (recipients of the process).

The central cancer registry operations use case diagram shows the hierarchical grouping of central cancer registry operations, starting with the general top-level functions and followed by the more detailed second-level functions.

The central cancer registry domain diagram shows the interactions between the entities involved in registry functions. It shows the formation of a cancer abstract from the time individual event reports are generated at different data sources to the time the cancer abstract is stored in the central cancer registry and made available to institutions and national programs for research.


Central cancer registry functions include—

  • Approve a pathology laboratory for electronic reporting
  • Prepare and transmit event report
  • Receive batch file
  • Validate event report
  • Perform patient linkage
  • Perform tumor linkage
  • Perform consolidation
  • Perform casefinding audit
  • Perform quality assurance/quality improvement
  • Perform external linkage to improve data
  • Conduct death clearance
  • Conduct active follow-up
  • Perform interstate data exchange
  • Respond to calls for data
  • Provide data for use by others
  • Conduct linkage for research
  • Perform rapid case ascertainment
  • Conduct research and analysis
  • Central cancer registry data sources include—

  • Hospitals
  • Freestanding pathology laboratories
  • Cancer treatment facilities
  • Freestanding healthcare practitioners
  • Pharmacies
  • Health insurance plans
  • Bureau of Vital Statistics
  • Census tract database
  • State health departments
  • IHS/local tribe clinics
  • National Death Index
  • Nursing homes/hospices
  • Freestanding diagnostic imaging centers
  • State cancer registries
  • Voter registration
  • Department of Motor Vehicles
  • Prisons
  • *Numbers rank the data sources on the quality of useful data available on a scale of 1 being the most useful and 10 being the least useful.
    **Pathology laboratories send data to both hospital registries and central cancer registries.

    Page last reviewed: November 9, 2011
    Page last updated: November 9, 2011
    Content source: Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion
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