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About the National Comprehensive Cancer Control Program

Since 1998, CDC’s National Comprehensive Cancer Control Program (NCCCP) has made great strides to reduce the burden of cancer in the United States. NCCCP supports 50 states, the District of Columbia, 7 tribal groups, and 7 U.S. Associated Pacific Islands/territories. They—

  • Establish coalitions.
  • Assess the burden of cancer.
  • Determine priorities.
  • Develop and implement cancer plans.

Comprehensive cancer control (CCC) programs across the nation work in their communities to promote healthy lifestyles and recommended cancer screenings, educate people about cancer symptoms, increase access to quality cancer care, and enhance cancer survivors’ quality of life.

The NCCCP’s updated logic model [PDF-1.3MB] represents the program’s growth and is based on the social ecological model. The logic model describes the theory of change, which outlines core program elements and priorities. It starts with a list of inputs (grantee resources) such as the CCC National Partnership, staff, and funds. It shows grantee activities, resulting outputs (grantee products), and outcomes on a short-, intermediate-, and long-term basis.

The NCCCP’s success is grounded in partnerships that reach across traditional divides to make CCC a reality in communities across the nation. CCC coalitions form an army of dedicated laypersons, professionals, and cancer survivors who share expertise, resources, and ideas to tackle priorities that are too broad to confront alone. The result is a powerful network of groups across the nation, working to reduce cancer and improve survivors’ quality of life.

Effective strategies for reducing cancer deaths and the number of new cases of cancer include ensuring that evidence-based screening tests and treatments are available and accessible, and reducing behavioral and environmental risk factors. Read examples of CCC programs in action.


Priorities for CDC-funded NCCC programs were established in 2010. They are to—

  • Emphasize primary prevention of cancer.
  • Support early detection and treatment activities.
  • Address public health needs of cancer survivors.
  • Implement policy, systems, and environmental changes to guide sustainable cancer control.
  • Promote health equity as it relates to cancer control.
  • Demonstrate outcomes through evaluation.

Ongoing Work

CDC continues to—

  • Support and promote interventions that address cancer disparities.
  • Offer ongoing technical assistance to programs that are developing and implementing CCC plans, including guidance on evaluating CCC to identify and measure accomplishments.
  • Support partnerships that strengthen cancer control at the national, state, and local levels.
  • Conduct public health translational research to inform program practice.
  • Broaden awareness of the CCC concept and its benefits.
  • Facilitate networking and peer-to-peer learning among the NCCCP’s 65 programs.
  • Disseminate best practices and evidence-based strategies.

These steps help support the best in partnership, program evaluation, and cancer control practice for improving the health of people in every stage of life—one of CDC’s primary health-protection goals.


CDC engages in research to define, confirm, and evaluate evidence-based interventions for cancer prevention and control. Our research is guided by NCCCP’s priorities, and results guide the adoption and implementation of interventions in different populations at state, tribal, and territorial levels.

NCCCP research projects include—

  • Comparing the effectiveness of tobacco cessation interventions. 24 NCCCP programs compared the effectiveness of telephone quit line and Web-based support services to help smokers quit.
  • Assessing physician knowledge of physical activity counseling. This project examines medical residents’ knowledge and comfort level in counseling patients to engage in physical activity to prevent cancer. This project is done in collaboration with Case Western University.
  • Estimating the level and capacity of colorectal cancer screening in the United States. This project estimates the number of people in 29 states who haven’t been screened for colorectal cancer, and the availability of services to screen them.
  • Surgical treatment and care among ovarian cancer survivors. This project aims to determine which ovarian cancer patients in two states receive appropriate and standard care to prolong survival and increase quality of life.
  • Measuring health behaviors and quality of life among cancer survivors. Several projects examine smoking, obesity, physical activity, and cancer screening behaviors among people diagnosed with cancer in the United States. Many studies use a special set of questions added to CDC’s Behavioral Risk Factor Surveillance System survey.
  • Collection and measurement of health behaviors among American Indian/Alaska Natives. This project is collecting specific health data from three American Indian tribes in the United States to help assess their cancer risk.
  • Use of evidence-based practices by cancer control planners. This project surveys all NCCCP programs to determine their knowledge and use of evidence-based interventions in cancer control.
  • Dissemination and uptake of CDC’s Inside Knowledge campaign materials. Six NCCCP programs disseminate Inside Knowledge: Get the Facts About Gynecologic Cancer campaign materials, and measure the uptake and saliency of the messages.
  • NCCCP cancer and action plan descriptions and analyses. We routinely analyze and publish the extent and content of NCCCP initiatives in various cancer-specific and NCCCP priority areas. Recent publications relate to tobacco, radon, and gynecologic cancer.

Critical Success Factors for the Future

  • A renewed focus on integrating programs that have natural connections.
  • Common policy agendas across the nation to support CCC plan priorities in a more focused way that helps share knowledge, skills, and resources.
  • Access to high-quality cancer services for more people.
  • More support from local, state, tribe, territory, and national government agencies, advocates, and private businesses.
  • More resources devoted to eliminating health disparities among underserved groups.
  • An ability to change processes as new solutions are found and levels of care and service increase.
  • Measuring the impact of CCC not just in terms of processes and plans, but also in human outcomes.
  • More research about CCC results.
  • More flexible ways of providing funds.