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HPV-Associated Cancers Statistics

A study that covered 100% of the U.S. population during 2004–2008 estimated that about 33,300 HPV-associated cancers occur each year. About 21,300 HPV-associated cancers occur each year among females, and about 12,100 occur each year among males. Cervical cancer is the most common HPV-associated cancer among women, and oropharyngeal cancers are the most common among men. The following counts are from this study.

Photograph of a group of people

This study used cancer registry data to estimate the amount of potentially HPV-associated cancer in the United States by examining cancer in parts of the body and cancer cell types that are more likely to be caused by HPV. Cancer registries do not collect data on the presence or absence of HPV in cancer tissue at the time of diagnosis.

In general, HPV is thought to be responsible for more than 90% of anal and cervical cancers and more than 50% of vaginal, vulvar, and penile cancers. Cancers of the head and neck are mostly caused by tobacco and alcohol, but recent studies show that about 60%–70% of cancers of the oropharynx may be linked to HPV. Many of these may be caused by a combination of tobacco, alcohol, and HPV. For more information, see How Many Cancers Are Linked with HPV Each Year?

 
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