Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

ABCs Report: Streptococcus pneumoniae, 2005

Active Bacterial Core Surveillance (ABCs): Emerging Infections Program Network

Print-friendly version of this surveillance report [1 page]

ABCs Areas

California (San Francisco County and children < 5 years in Alameda and Contra Costa counties); Colorado (5 county Denver area); Connecticut; Georgia (20 county Atlanta area); Maryland (6 county Baltimore area); Minnesota; New Mexico; New York (15 county Rochester and Albany areas and children < 5 years in Erie county); Oregon (3 county Portland area); Tennessee (11 urban counties)

ABCs Population

The surveillance areas represent 27,816,784 persons. Source: National Center for Health Statistics bridged-race vintage 2005 postcensal file

ABCs Case Definition

Invasive pneumococcal disease: isolation of Streptococcus pneumoniae from normally sterile site in resident of a surveillance area in 2005.

ABCs Methodology

ABCs personnel routinely contacted all microbiology laboratories serving acute care hospitals in their area to identify cases. Standardized case report forms that include information on demographic characteristics, clinical syndrome, and outcome of illness were completed for each identified case. Pneumococcal isolates were collected and sent to reference laboratories for susceptibility testing using NCCLS methods and serotyping. Regular laboratory audits assessed completeness of active surveillance and detected additional cases.

Rates of invasive pneumococcal disease were calculated using population estimates for 2005. For national estimates, race- and age-specific rates of disease were applied from the aggregate surveillance area to the age and racial distribution of the 2005 U.S. population. Cases with unknown race were distributed by area based on reported race distribution for known cases within the eight age categories.

Reported ABCs Profiles

Race No. (Rate*)
White 2,709 (12.3)
Black 1,056 (25.0)
Other 143 (8.9)

Unknown race (n=620) distributed amongst known

* Cases per 100,000 population for ABCs areas

Citation

Centers for Disease Control and Prevention. 2006. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Streptococcus pneumoniae, 2005.

Age (years) Cases
No. (Rate*)
Deaths
No. (Rate*)
<1

153 (36.2)

4 (0.97)
1

151 (35.6)

1 (0.24)
2-4 155 (12.3) 4 (0.33)
5-17 146 (3.0) 5 (0.10)
18-34 264 (4.1) 11 (0.17)
35-49 842 (12.9) 74 (1.1)
50-64 969 (20.5) 127 (2.7)
≥ 65 1,228 (39.6) 212 (6.8)
Total 3,908 (14.1) 438 (1.6)

*Cases or deaths per 100,000 population for ABCs areas

Syndrome No. (%*)
Meningitis 226 (5.8)
Bacteremia without focus 864 (22.1)
Pneumonia with bacteremia 2,683 (68.7)

*Percent of cases

Antibiotic Susceptibility S*
%
I
%
R
%
Penicillin 76.4 13.7 9.9
Cefotaxime 94.7 4.1 1.2
Erythromycin 79.8 0.1 20.1
TMP/Sulfa 78.1 6.9 15.0
Tetracycline 90.6 0.1 9.3
Levofloxacin 99.4 0.03 0.6
Vancomycin 100.0 0.0 0.0

Based on reference lab testing of 3,499 isolates

* Susceptible; Intermediate; Resistant based on year 2005 NCCLS definitions

National Estimates of Invasive Disease

Cases: 41,550 (14.0/100,000)
Deaths: 4,850 (1.6/100,000)

Healthy People 2010 Update

Objective: Decrease the incidence of invasive pneumococcal infections to 46 per 100,000 persons less than 5 years of age and to 42 per 100,000 persons aged 65 and older.

Age (year) 2010 Objective 2005 Rate*
< 5 46/100,000 21.2/100,000
≥ 65 42/100,000 39.6/100,000

*Cases per 100,000 U.S. population < 5 years or ≥ 65 years

Top of Page

Images and logos on this website which are trademarked/copyrighted or used with permission of the trademark/copyright or logo holder are not in the public domain. These images and logos have been licensed for or used with permission in the materials provided on this website. The materials in the form presented on this website may be used without seeking further permission. Any other use of trademarked/copyrighted images or logos requires permission from the trademark/copyright holder...more

External Web Site Policy This graphic notice means that you are leaving an HHS Web site. For more information, please see the Exit Notification and Disclaimer policy.

 
Contact Us:
  • Centers for Disease Control and Prevention
    1600 Clifton Rd
    Atlanta, GA 30333
  • 800-CDC-INFO
    (800-232-4636)
    TTY: (888) 232-6348
    Contact CDC-INFO
USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO
A-Z Index
  1. A
  2. B
  3. C
  4. D
  5. E
  6. F
  7. G
  8. H
  9. I
  10. J
  11. K
  12. L
  13. M
  14. N
  15. O
  16. P
  17. Q
  18. R
  19. S
  20. T
  21. U
  22. V
  23. W
  24. X
  25. Y
  26. Z
  27. #