ABCs Report: group B Streptococcus, 2000

Active Bacterial Core Surveillance (ABCs): Emerging Infections Program Network

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ABCs Areas

California (3 county San Francisco Bay area); Connecticut; Georgia (20 county Atlanta area); Maryland; Minnesota; New York (7 county Rochester area and 8 county Albany area); Oregon (3 county Portland area); Tennessee (11 urban counties)

ABCs Population

The surveillance areas represent 27,275,642 persons and 363,214 persons <1 yr. Source: U.S. Bureau of the Census,
2000

ABCs Case Definition

Invasive group B streptococcal disease: isolation of group B streptococcus from a normally sterile site in a resident of a surveillance area in 2000. Early-onset cases occur at <7 days of age and late-onset occur between 7 and 90 days of age.

ABCs Methodology

Project personnel communicated at least monthly with contacts in all microbiology laboratories serving acute care hospitals in their area to identify cases. Standardized case report forms that include information on demographic characteristics, clinical syndrome, and outcome of illness were completed for each identified case. Regular laboratory audits assess completeness of active surveillance and detect additional cases.

Rates of invasive group B streptococcal disease were calculated using U.S. Bureau of the Census population estimates for 2000. Rates of early-onset and late -onset group B streptococcal disease were calculated using population estimates for persons <1 yr for 2000. For national projections of cases, race- and age-specific rates of disease were applied from the aggregate surveillance area to the age and racial distribution of the 2000 U. S. population. Cases with unknown race were distributed by area based on reported race distribution for known cases within the eight age categories.

Reported ABCs Profiles

Race	No.	(Rate*)
White	1,243	(6.3)
Black	543	(12.2)
Other	54	(1.8)

Unknown race (n=233) distributed amongst knowns.

^* Cases per 100,000 population for ABCs areas.

Ethnicity	No.	(Rate*)
Hispanic	90	(5.1)
Non-Hispanic	766	------
Unknown	984	------

^*Cases per 100,000 population for ABCs areas.

Age (years)	Cases No. (Rate*)	Deaths No. (Rate*)
<1	360 (99.1)	20 (5.5)
1	1 (0.3)	0 (0.0)
2-4	1 (0.1)	0 (0.1)
5-17	14 (0.3)	2 (0.4)
18-34	130 (2.0)	4 (0.1)
35-49	253 (3.8)	25 (0.4)
50-64	389 (9.6)	33 (0.8)
≥ 65	692 (22.5)	97 (3.2)
Total	1,840 (6.8)	182 (0.7)

^*Cases or deaths per 100,000 population for AB

Race	Early-Onset No. (Rate*)	Late-Onset No. (Rate*)
White	305	(33.3)
Black	55	(6.0)
Other	128	(14.0)
Total	201 (0.6)	141 (0.4)

^* Cases per 1,000 live births for ABCs areas

National Estimates of Invasive Disease

Early-Onset Cases: 2000 (0.5/1,000 live births)
Late-Onset Cases: 1,300 (0.3/1,000 live births)
Total Cases: 18,700 (6.7/100,000 population)
Deaths: 1,900 (0.7/100,000 population)

Healthy People 2010 Update

Early-Onset Disease

Objective: Decrease the incidence of invasive early-onset group B streptococcal disease to 0.5 cases per 1,000 live births.

Race	2010 Objective	2000 Rate*
White	0.5/1,000	0.5/1,000
Black	0.5/1,000	1.0/1,000
Other	0.5/1,000	1.0/1,000
Total	0.5/1,000	0.5/1,000

*Projected cases per 1,000 persons < 1 yr

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