ABCs Isolate Bank: Isolates and Information Currently Available 

12/18/2008

(Table 1)

Organism:  Streptococcus pneumoniae	
Year (number of unique strains): 1995 (n=1752)	
Demographic and clinical data available:  Age groups: less than 1 yr, 1 yr, 2-4 yrs, 5-17 yrs, 18-34 yrs, 35-49 yrs, 50-64 yrs, > 65 yrs
Source: CSF, blood or other sterile site
Laboratory testing results available:  1) Serotype 2) MIC§ results to the following antibiotics: amoxicillin, cefaclor, cefotaxime, chloramphenicol, clindamycin, erythromycin, meropenem, ofloxacin, penicillin, rifampin, Synercid, TMP/Sulfa, vancomycin

Organism:  Streptococcus pneumoniae	
Year (number of unique strains): 1996 (n=1328), 1997 (n=1721)
Demographic and clinical data available:  Age groups: less than 1 yr, 1 yr, 2-4 yrs, 5-17 yrs, 18-34 yrs, 35-49 yrs, 50-64 yrs, > 65 yrs
Source: CSF, blood or other sterile site
Laboratory testing results available:  1) Serotype
2) MIC§ results to the following antibiotics: amoxicillin, cefaclor, cefotaxime, chloramphenicol, clindamycin, erythromycin, meropenem, ofloxacin, penicillin, rifampin, Synercid, tetracycline, TMP/Sulfa, vancomycin

Organism:  Streptococcus pneumoniae	
Year (number of unique strains): 1998 (n=4095)	
Demographic and clinical data available:  Age groups: less than 1 yr, 1 yr, 2-4 yrs, 5-17 yrs, 18-34 yrs, 35-49 yrs, 50-64 yrs, > 65 yrs
Source:  CSF, blood or other sterile site
Laboratory testing results available:  1) Serotype
2) 1998: MIC§ results to the following antibiotics: amoxicillin, cefotaxime, cefuroxime, chloramphenicol, clindamycin, erythromycin, levofloxacin, meropenem, penicillin, rifampin, Synercid, tetracycline, TMP/Sulfa, trovafloxacin, vancomycin

Organism:  Streptococcus pneumoniae	
Year (number of unique strains): 1999 (n=3975), 2000 (n=3818)
Demographic and clinical data available:  Age groups: less than 1 yr, 1 yr, 2-4 yrs, 5-17 yrs, 18-34 yrs, 35-49 yrs, 50-64 yrs, > 65 yrs
Source: CSF, blood or other sterile site
Laboratory testing results available: 1999/2000: same as 1998 except for MIC testing of fluoroquinolones: gatifloxacin and levofloxacin only

Organism:  Streptococcus pneumoniae	
Year (number of unique strains):  2001 (n=3091), 2002 (n=3151), 2003 (n=3281)
Demographic and clinical data available: Age groups: less than 1 yr, 1 yr, 2-4 yrs, 5-17 yrs, 18-34 yrs, 35-49 yrs, 50-64 yrs, > 65 yrs
Source: CSF, blood or other sterile site
Laboratory testing results available:  2001/2002/2003: same as 1998 except for MIC testing of fluoroquinolones: levofloxacin, ciprofloxacin, and sparfloxacin only.  Linezolid added. 

Organism: Streptococcus pneumoniae	
Year (number of unique strains): 2004 (n=3132), 2005 (n=3560) 
Demographic and clinical data available: Age groups: less than 1 yr, 1 yr, 2-4 yrs, 5-17 yrs, 18-34 yrs, 35-49 yrs, 50-64 yrs, > 65 yrs
Source: CSF, blood or other sterile site
Laboratory testing results available: 2004/2005/2006/2007 same as 1998 except for MIC testing of telithromycin, and ceftriaxone added; 

Organism: group A Streptococcus
Year (number of unique strains): 1995 (n=280), 1996 (n=343),  1997 (n=674),  1998 (n=627),    
1999 (n=838), 2000 (n=542), 2001 (n=419), 2002 (n=852), 2003 (n=1075), 2004 (n=864), 2005 (n=893)
Demographic and clinical data available: Presence or absence of the following severe infection: NF*, STSS**, puerperal sepsis
Laboratory testing results available: emm type 
Presence or absence of sof

Organism: group B Streptococcus	
Year (number of unique strains): 1995 (n=23), 1996 (n=42), 1997 (n=65), 1998 (n=426), 1999 (n=518), 2000 (n=321), 2001 (n=310), 2002 (n=721), 2003 (n=1144), 2004 (n=1332), 2005 (n=1442)
Demographic and clinical data available:  Source: CSF, blood or other sterile site 
For age groups: less than 1 year: onset [early ("0-6 days"), late ("7-89 days") or other (>90 days)]; 
1-49 yrs: pregnant (yes, no, unknown);
50-64 yrs and > 65 yrs: age group only
Laboratory testing results available: Serotype

(Table ends)

Footnotes:
* Necrotizing fasciitis
** Streptococcal toxic shock syndrome
§ Minimal Inhibitory Concentration 


Explanation of antibiotic abbreviations:
Sorted by abbreviation:

AMO - Amoxicillin 
AMP - Ampicillin 
CFX - Cefuroxime 
CFT - Ceftriaxone
CHL - Chloramphenicol 
CIP - Ciprofloxacin 
CLA - Clarithromycin 
CLI - Clindamycin 
COT - TMP/sulfamethoxazole
CZL - Cefazolin 
ERY - Erythromycin 
FAC - Cefaclor 
FOX - Cefoxotin 
GFX - Gatifloxacin 
IMI - Imipenem 
LFX - Levofloxacin 
LZO  -	Linezolid 
MER  -	Meropenem
OFL -	Ofloxacin 
PEN  -	Penicillin 
RIF  -	Rifampin
SPA  -	Sparfloxacin 
SYN  -	Synercid 
TAX  -	Cefotaxime 
TEL -	Telithromycin
TET  -	Tetracycline 
TVA  -	Trovafloxacin 
VAN  -	Vancomycin