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Rabies

ACIP votes to recommend reduced rabies vaccination series

Posted: June 24, 2009

7/10/2009: ACIP Provisional Recommendations for Prevention of RabiesPDF Document Icon

picture of needle and 4 vials of vaccine

At the June 24, 2009 Advisory Committee on Immunization Practices (ACIP) meeting, the rabies working group presented evidence in support of a recommendation to reduce the number of vaccine doses in the human rabies postexposure prophylaxis (PEP) series from 5 to 4 doses.  After much discussion, ACIP voted in favor of accepting the recommendation. 

This will effectively change the 2008 ACIP recommendations PDF Document Icon for human rabies prevention as follows: the  PEP series will consist of the administration of human rabies immune globulin (20IU/kg body weight) on day 0 and 4 doses of vaccine (1ml administered intramuscularly) on days 0, 3, 7, and 14.  Formal publication of the recommendations will be forthcoming.  Additional information on ACIP, and minutes of past meetings, can be found at the ACIP website.

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Page last modified: July 10, 2009
Page last reviewed: June 30, 2009
Content Source: National Center for Zoonotic, Vector-Borne, & Enteric Diseases (ZVED)